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Items: 1 to 20 of 23

1.

REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.

Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V.

Oncotarget. 2017 Dec 28;9(4):5233-5250. doi: 10.18632/oncotarget.23750. eCollection 2018 Jan 12.

2.

The Dual Role of Bone Morphogenetic Proteins in Cancer.

Bach DH, Park HJ, Lee SK.

Mol Ther Oncolytics. 2017 Oct 24;8:1-13. doi: 10.1016/j.omto.2017.10.002. eCollection 2018 Mar 30. Review.

3.

Multi-physics interactions drive VEGFR2 relocation on endothelial cells.

Damioli V, Salvadori A, Beretta GP, Ravelli C, Mitola S.

Sci Rep. 2017 Dec 1;7(1):16700. doi: 10.1038/s41598-017-16786-4.

4.

A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site.

Li J, Liu H, Zou L, Ke J, Zhang Y, Zhu Y, Yang Y, Gong Y, Tian J, Zou D, Peng X, Gong J, Zhong R, Huang K, Chang J, Miao X.

Oncotarget. 2017 May 23;8(37):61318-61326. doi: 10.18632/oncotarget.18095. eCollection 2017 Sep 22.

5.

Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation.

Ghouleh IA, Sahoo S, Meijles DN, Amaral JH, de Jesus DS, Sembrat J, Rojas M, Goncharov DA, Goncharova EA, Pagano PJ.

Clin Sci (Lond). 2017 Jul 16;131(15):2019-2035. doi: 10.1042/CS20160812. Print 2017 Aug 1.

PMID:
28522681
6.

Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension.

Barnes JW, Kucera ET, Tian L, Mellor NE, Dvorina N, Baldwin WW 3rd, Aldred MA, Farver CF, Comhair SA, Aytekin M, Dweik RA.

Am J Respir Cell Mol Biol. 2016 Oct;55(4):564-575.

7.

Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist.

Grillo E, Ravelli C, Corsini M, Ballmer-Hofer K, Zammataro L, Oreste P, Zoppetti G, Tobia C, Ronca R, Presta M, Mitola S.

Oncotarget. 2016 Jun 7;7(23):35353-68. doi: 10.18632/oncotarget.9286.

8.

β3 Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand.

Ravelli C, Grillo E, Corsini M, Coltrini D, Presta M, Mitola S.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2161-71. doi: 10.1161/ATVBAHA.115.306230. Epub 2015 Aug 20.

9.

Gremlin, a bone morphogenetic protein antagonist, is a crucial angiogenic factor in pituitary adenoma.

Koketsu K, Yoshida D, Kim K, Ishii Y, Tahara S, Teramoto A, Morita A.

Int J Endocrinol. 2015;2015:834137. doi: 10.1155/2015/834137. Epub 2015 Mar 5.

10.

Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.

Domigan CK, Ziyad S, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):30-9. doi: 10.1161/ATVBAHA.114.303215. Epub 2014 Oct 2. Review.

11.

Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection.

Wellbrock J, Sheikhzadeh S, Oliveira-Ferrer L, Stamm H, Hillebrand M, Keyser B, Klokow M, Vohwinkel G, Bonk V, Otto B, Streichert T, Balabanov S, Hagel C, Rybczynski M, Bentzien F, Bokemeyer C, von Kodolitsch Y, Fiedler W.

PLoS One. 2014 Aug 12;9(8):e104742. doi: 10.1371/journal.pone.0104742. eCollection 2014.

12.

Identification of a gene expression driven progression pathway in myxoid liposarcoma.

De Cecco L, Negri T, Brich S, Mauro V, Bozzi F, Dagrada G, Disciglio V, Sanfilippo R, Gronchi A, D'Incalci M, Casali PG, Canevari S, Pierotti MA, Pilotti S.

Oncotarget. 2014 Aug 15;5(15):5965-77.

13.

The DAN family: modulators of TGF-β signaling and beyond.

Nolan K, Thompson TB.

Protein Sci. 2014 Aug;23(8):999-1012. doi: 10.1002/pro.2485. Epub 2014 Jun 2. Review.

14.

Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1.

Karagiannis GS, Berk A, Dimitromanolakis A, Diamandis EP.

Mol Oncol. 2013 Aug;7(4):826-39. doi: 10.1016/j.molonc.2013.04.002. Epub 2013 Apr 18.

15.

Gremlin induces cell proliferation and extra cellular matrix accumulation in mouse mesangial cells exposed to high glucose via the ERK1/2 pathway.

Huang H, Huang H, Li Y, Liu M, Shi Y, Chi Y, Zhang T.

BMC Nephrol. 2013 Feb 11;14:33. doi: 10.1186/1471-2369-14-33.

16.

Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells.

Mulvihill MS, Kwon YW, Lee S, Fang LT, Choi H, Ray R, Kang HC, Mao JH, Jablons D, Kim IJ.

PLoS One. 2012;7(8):e42264. doi: 10.1371/journal.pone.0042264. Epub 2012 Aug 1.

17.

Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior.

Heinke J, Kerber M, Rahner S, Mnich L, Lassmann S, Helbing T, Werner M, Patterson C, Bode C, Moser M.

Oncogene. 2012 Jun 14;31(24):2919-30. doi: 10.1038/onc.2011.473. Epub 2011 Oct 24.

18.

Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates.

Wiley DM, Jin SW.

Semin Cell Dev Biol. 2011 Dec;22(9):1012-8. doi: 10.1016/j.semcdb.2011.10.005. Epub 2011 Oct 12. Review.

19.

Distinct functionalities of bone morphogenetic protein antagonists during fracture healing in mice.

Dean DB, Watson JT, Jin W, Peters C, Enders JT, Chen A, Moed BR, Zhang Z.

J Anat. 2010 May;216(5):625-30. doi: 10.1111/j.1469-7580.2010.01214.x. Epub 2010 Mar 5.

20.

Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.

van Vlodrop IJ, Baldewijns MM, Smits KM, Schouten LJ, van Neste L, van Criekinge W, van Poppel H, Lerut E, Schuebel KE, Ahuja N, Herman JG, de Bruïne AP, van Engeland M.

Am J Pathol. 2010 Feb;176(2):575-84. doi: 10.2353/ajpath.2010.090442. Epub 2009 Dec 30.

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