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Items: 8


IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.

Schinke C, Giricz O, Li W, Shastri A, Gordon S, Barreyro L, Bhagat T, Bhattacharyya S, Ramachandra N, Bartenstein M, Pellagatti A, Boultwood J, Wickrema A, Yu Y, Will B, Wei S, Steidl U, Verma A.

Blood. 2015 May 14;125(20):3144-52. doi: 10.1182/blood-2015-01-621631. Erratum in: Blood. 2015 Jul 16;126(3):425. Barreryo, Laura [corrected to Barreyro, Laura].


The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers.

Costantino VV, Mansilla SF, Speroni J, Amaya C, Cuello-CarriĆ³n D, Ciocca DR, Priestap HA, Barbieri MA, Gottifredi V, Lopez LA.

PLoS One. 2013;8(1):e53168. doi: 10.1371/journal.pone.0053168.


Blockade of the sonic hedgehog pathway effectively inhibits the growth of hepatoma in mice: An in vivo study.

Jeng KS, Sheen IS, Jeng WJ, Yu MC, Tsai HH, Chang FY, Su JC.

Oncol Lett. 2012 Dec;4(6):1158-1162.


Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors.

Dettman EJ, Simko SJ, Ayanga B, Carofino BL, Margolin JF, Morse HC 3rd, Justice MJ.

Oncogene. 2011 Jun 23;30(25):2859-73. doi: 10.1038/onc.2011.12.


The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell.

Zipori D.

Cancer Microenviron. 2010 Feb 5;3(1):15-28. doi: 10.1007/s12307-009-0034-7.


Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.

Park S, Chapuis N, Tamburini J, Bardet V, Cornillet-Lefebvre P, Willems L, Green A, Mayeux P, Lacombe C, Bouscary D.

Haematologica. 2010 May;95(5):819-28. doi: 10.3324/haematol.2009.013797. Review.


Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.

Libura J, Ward M, Solecka J, Richardson C.

Eur J Haematol. 2008 Sep;81(3):185-95. doi: 10.1111/j.1600-0609.2008.01103.x.

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