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Oxidative Stress in COPD: Sources, Markers, and Potential Mechanisms.

McGuinness AJ, Sapey E.

J Clin Med. 2017 Feb 15;6(2). pii: E21. doi: 10.3390/jcm6020021. Review.


The role of the endothelium in asthma and chronic obstructive pulmonary disease (COPD).

Green CE, Turner AM.

Respir Res. 2017 Jan 18;18(1):20. doi: 10.1186/s12931-017-0505-1. Review.


Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease.

Chiuchiolo MJ, Crystal RG.

Ann Am Thorac Soc. 2016 Aug;13 Suppl 4:S352-69. doi: 10.1513/AnnalsATS.201506-344KV.


Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema.

Ni K, Serban KA, Batra C, Petrache I.

Ann Am Thorac Soc. 2016 Aug;13 Suppl 4:S311-6. doi: 10.1513/AnnalsATS.201510-675KV.


Peptides from American alligator plasma are antimicrobial against multi-drug resistant bacterial pathogens including Acinetobacter baumannii.

Barksdale SM, Hrifko EJ, Chung EM, van Hoek ML.

BMC Microbiol. 2016 Aug 19;16(1):189. doi: 10.1186/s12866-016-0799-z.


α-Linoleic acid enhances the capacity of α-1 antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophils.

Aggarwal N, Korenbaum E, Mahadeva R, Immenschuh S, Grau V, Dinarello CA, Welte T, Janciauskiene S.

Mol Med. 2016 Jul 13;22. doi: 10.2119/molmed.2016.00119. [Epub ahead of print]


Alpha-1 Antitrypsin Prevents the Development of Preeclampsia Through Suppression of Oxidative Stress.

Feng Y, Xu J, Zhou Q, Wang R, Liu N, Wu Y, Yuan H, Che H.

Front Physiol. 2016 May 24;7:176. doi: 10.3389/fphys.2016.00176. eCollection 2016.


Ocular Fluid As a Replacement for Serum in Cell Cryopreservation Media.

Varma VP, Devi L, Venna NK, Murthy ChL, Idris MM, Goel S.

PLoS One. 2015 Jul 2;10(7):e0131291. doi: 10.1371/journal.pone.0131291. eCollection 2015.


Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells.

Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu D, Predescu S, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L425-34. doi: 10.1152/ajplung.00376.2014. Epub 2015 Jun 19.


Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option?

Ortiz G, Salica JP, Chuluyan EH, Gallo JE.

Biol Res. 2014 Nov 18;47:58. doi: 10.1186/0717-6287-47-58. Review.


Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones.

Frump AL, Goss KN, Vayl A, Albrecht M, Fisher A, Tursunova R, Fierst J, Whitson J, Cucci AR, Brown MB, Lahm T.

Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L873-90. doi: 10.1152/ajplung.00006.2015. Epub 2015 Feb 20.


Comparative proteomic study reveals the molecular aspects of delayed ocular symptoms induced by sulfur mustard.

Pashandi Z, Saraygord-Afshari N, Naderi-Manesh H, Naderi M.

Int J Proteomics. 2015;2015:659241. doi: 10.1155/2015/659241. Epub 2015 Jan 21.


Acute-phase protein α1-anti-trypsin: diverting injurious innate and adaptive immune responses from non-authentic threats.

Guttman O, Baranovski BM, Schuster R, Kaner Z, Freixo-Lima GS, Bahar N, Kalay N, Mizrahi MI, Brami I, Ochayon DE, Lewis EC.

Clin Exp Immunol. 2015 Feb;179(2):161-72. doi: 10.1111/cei.12476. Review.


α1-Antitrypsin activates protein phosphatase 2A to counter lung inflammatory responses.

Geraghty P, Eden E, Pillai M, Campos M, McElvaney NG, Foronjy RF.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1229-42. doi: 10.1164/rccm.201405-0872OC.


Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer.

Kwon CH, Park HJ, Lee JR, Kim HK, Jeon TY, Jo HJ, Kim DH, Kim GH, Park DY.

Br J Cancer. 2014 Nov 11;111(10):1993-2002. doi: 10.1038/bjc.2014.490. Epub 2014 Sep 11.


Regulation of autophagy by α1-antitrypsin: "a foe of a foe is a friend".

Shapira MG, Khalfin B, Lewis EC, Parola AH, Nathan I.

Mol Med. 2014 Oct 27;20:417-26. doi: 10.2119/molmed.2014.00054.


Proteomic changes of alveolar lining fluid in illnesses associated with exposure to inhaled non-infectious microbial particles.

Teirilä L, Karvala K, Ahonen N, Riska H, Pietinalho A, Tuominen P, Piirilä P, Puustinen A, Wolff H.

PLoS One. 2014 Jul 17;9(7):e102624. doi: 10.1371/journal.pone.0102624. eCollection 2014.


Immune-modulating effects of alpha-1 antitrypsin.

Ehlers MR.

Biol Chem. 2014 Oct;395(10):1187-93. doi: 10.1515/hsz-2014-0161. Review.


Rapid renal alpha-1 antitrypsin gene induction in experimental and clinical acute kidney injury.

Zager RA, Johnson AC, Frostad KB.

PLoS One. 2014 May 21;9(5):e98380. doi: 10.1371/journal.pone.0098380. eCollection 2014.


Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.

Saferali A, Lee J, Sin DD, Rouhani FN, Brantly ML, Sandford AJ.

PLoS One. 2014 Apr 24;9(4):e95600. doi: 10.1371/journal.pone.0095600. eCollection 2014.

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