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Items: 1 to 20 of 75

1.

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model.

de Boeck M, Cui C, Mulder AA, Jost CR, Ikeno S, Ten Dijke P.

Sci Rep. 2016 Apr 26;6:24968. doi: 10.1038/srep24968.

2.

Structure of Gremlin-1 and analysis of its interaction with BMP-2.

Kišonaitė M, Wang X, Hyvönen M.

Biochem J. 2016 Jun 1;473(11):1593-604. doi: 10.1042/BCJ20160254. Epub 2016 Apr 1.

3.

Gene Expression Profiling of Gastric Cancer.

Marimuthu A, Jacob HK, Jakharia A, Subbannayya Y, Keerthikumar S, Kashyap MK, Goel R, Balakrishnan L, Dwivedi S, Pathare S, Dikshit JB, Maharudraiah J, Singh S, Sameer Kumar GS, Vijayakumar M, Veerendra Kumar KV, Premalatha CS, Tata P, Hariharan R, Roa JC, Prasad TS, Chaerkady R, Kumar RV, Pandey A.

J Proteomics Bioinform. 2011 Apr;4(4):74-82. Epub 2011 Apr 16.

4.

Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype.

Moarii M, Reyal F, Vert JP.

Hum Genomics. 2015 Oct 13;9:26. doi: 10.1186/s40246-015-0048-9.

5.

β3 Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand.

Ravelli C, Grillo E, Corsini M, Coltrini D, Presta M, Mitola S.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2161-71. doi: 10.1161/ATVBAHA.115.306230. Epub 2015 Aug 20.

6.

Gremlin is a key pro-fibrogenic factor in chronic pancreatitis.

Staloch D, Gao X, Liu K, Xu M, Feng X, Aronson JF, Falzon M, Greeley GH, Rastellini C, Chao C, Hellmich MR, Cao Y, Ko TC.

J Mol Med (Berl). 2015 Oct;93(10):1085-93. doi: 10.1007/s00109-015-1308-9. Epub 2015 Jul 5.

7.
8.

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma.

Bolomsky A, Hose D, Schreder M, Seckinger A, Lipp S, Klein B, Heintel D, Ludwig H, Zojer N.

J Hematol Oncol. 2015 Feb 8;8:10. doi: 10.1186/s13045-014-0105-1.

9.

Gremlin, a bone morphogenetic protein antagonist, is a crucial angiogenic factor in pituitary adenoma.

Koketsu K, Yoshida D, Kim K, Ishii Y, Tahara S, Teramoto A, Morita A.

Int J Endocrinol. 2015;2015:834137. doi: 10.1155/2015/834137. Epub 2015 Mar 5.

10.

Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC.

Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042.

11.

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.

Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, Rodenas-Cuadrado P, Mallappa S, Clark S, Thomas H, Jeffery R, Poulsom R, Rodriguez-Justo M, Novelli M, Chetty R, Silver A, Sansom OJ, Greten FR, Wang LM, East JE, Tomlinson I, Leedham SJ.

Nat Med. 2015 Jan;21(1):62-70. doi: 10.1038/nm.3750. Epub 2014 Dec 1.

12.

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.

Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC.

Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13.

13.

Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.

Kobayashi J, Yoshida M, Tarui S, Hirata M, Nagai Y, Kasahara S, Naruse K, Ito H, Sano S, Oh H.

PLoS One. 2014 Jul 22;9(7):e102796. doi: 10.1371/journal.pone.0102796. eCollection 2014.

14.

Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.

Yan K, Wu Q, Yan DH, Lee CH, Rahim N, Tritschler I, DeVecchio J, Kalady MF, Hjelmeland AB, Rich JN.

Genes Dev. 2014 May 15;28(10):1085-100. doi: 10.1101/gad.235515.113. Epub 2014 May 1.

15.

Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk.

Yang H, Gao Y, Feng T, Jin TB, Kang LL, Chen C.

PLoS One. 2014 Feb 24;9(2):e89736. doi: 10.1371/journal.pone.0089736. eCollection 2014.

16.

Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell.

Donnelly JM, Engevik AC, Engevik M, Schumacher MA, Xiao C, Yang L, Worrell RT, Zavros Y.

Dig Dis Sci. 2014 Mar;59(3):569-82. doi: 10.1007/s10620-013-2927-z. Epub 2013 Nov 8.

17.

Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice.

Müller I, Schönberger T, Schneider M, Borst O, Ziegler M, Seizer P, Leder C, Müller K, Lang M, Appenzeller F, Lunov O, Büchele B, Fahrleitner M, Olbrich M, Langer H, Geisler T, Lang F, Chatterjee M, de Boer JF, Tietge UJ, Bernhagen J, Simmet T, Gawaz M.

J Biol Chem. 2013 Nov 1;288(44):31635-45. doi: 10.1074/jbc.M113.477745. Epub 2013 Sep 3.

18.

Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug.

Tamminen JA, Parviainen V, Rönty M, Wohl AP, Murray L, Joenväärä S, Varjosalo M, Leppäranta O, Ritvos O, Sengle G, Renkonen R, Myllärniemi M, Koli K.

Oncogenesis. 2013 Aug 26;2:e66. doi: 10.1038/oncsis.2013.29.

19.

Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion.

Owens P, Polikowsky H, Pickup MW, Gorska AE, Jovanovic B, Shaw AK, Novitskiy SV, Hong CC, Moses HL.

PLoS One. 2013 Jun 28;8(6):e67533. doi: 10.1371/journal.pone.0067533. Print 2013.

20.

The expression patterns of gremlin 1 and noggin in normal adult and tumor tissues.

Laurila R, Parkkila S, Isola J, Kallioniemi A, Alarmo EL.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1400-8. Print 2013.

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