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Items: 1 to 20 of 47


Helical jackknives control the gates of the double-pore K+ uptake system KtrAB.

Diskowski M, Mehdipour AR, Wunnicke D, Mills DJ, Mikusevic V, Bärland N, Hoffmann J, Morgner N, Steinhoff HJ, Hummer G, Vonck J, Hänelt I.

Elife. 2017 May 16;6. pii: e24303. doi: 10.7554/eLife.24303.


Understanding the conformational motions of RCK gating rings.

Giraldez T, Rothberg BS.

J Gen Physiol. 2017 Apr 3;149(4):431-441. doi: 10.1085/jgp.201611726. Epub 2017 Feb 28. Review.


Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter.

Szollosi A, Vieira-Pires RS, Teixeira-Duarte CM, Rocha R, Morais-Cabral JH.

PLoS Biol. 2016 Jan 15;14(1):e1002356. doi: 10.1371/journal.pbio.1002356. eCollection 2016 Jan.


Calcium ions open a selectivity filter gate during activation of the MthK potassium channel.

Posson DJ, Rusinova R, Andersen OS, Nimigean CM.

Nat Commun. 2015 Sep 23;6:8342. doi: 10.1038/ncomms9342.


Structure of potassium channels.

Kuang Q, Purhonen P, Hebert H.

Cell Mol Life Sci. 2015 Oct;72(19):3677-93. doi: 10.1007/s00018-015-1948-5. Epub 2015 Jun 13. Review.


Crystal structure of a two-subunit TrkA octameric gating ring assembly.

Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA.

PLoS One. 2015 Mar 31;10(3):e0122512. doi: 10.1371/journal.pone.0122512. eCollection 2015.


Recent progress on the structure and function of the TrkH/KtrB ion channel.

Levin EJ, Zhou M.

Curr Opin Struct Biol. 2014 Aug;27:95-101. doi: 10.1016/ Epub 2014 Jul 8. Review.


Conformational changes underlying pore dilation in the cytoplasmic domain of mammalian inward rectifier K+ channels.

Inanobe A, Nakagawa A, Kurachi Y.

PLoS One. 2013 Nov 11;8(11):e79844. doi: 10.1371/journal.pone.0079844. eCollection 2013.


A BK (Slo1) channel journey from molecule to physiology.

Contreras GF, Castillo K, Enrique N, Carrasquel-Ursulaez W, Castillo JP, Milesi V, Neely A, Alvarez O, Ferreira G, González C, Latorre R.

Channels (Austin). 2013 Nov-Dec;7(6):442-58. doi: 10.4161/chan.26242. Epub 2013 Sep 11. Review.


Gating of the TrkH ion channel by its associated RCK protein TrkA.

Cao Y, Pan Y, Huang H, Jin X, Levin EJ, Kloss B, Zhou M.

Nature. 2013 Apr 18;496(7445):317-22. doi: 10.1038/nature12056.


Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.

Kong C, Zeng W, Ye S, Chen L, Sauer DB, Lam Y, Derebe MG, Jiang Y.

Elife. 2012 Dec 13;1:e00184. doi: 10.7554/eLife.00184.


Perspectives on: conformational coupling in ion channels: conformational coupling in BK potassium channels.

Horrigan FT.

J Gen Physiol. 2012 Dec;140(6):625-34. doi: 10.1085/jgp.201210849.


Crystal structure of a Ba(2+)-bound gating ring reveals elementary steps in RCK domain activation.

Smith FJ, Pau VP, Cingolani G, Rothberg BS.

Structure. 2012 Dec 5;20(12):2038-47. doi: 10.1016/j.str.2012.09.014. Epub 2012 Oct 18.


The BK channel: a vital link between cellular calcium and electrical signaling.

Rothberg BS.

Protein Cell. 2012 Dec;3(12):883-92. doi: 10.1007/s13238-012-2076-8. Epub 2012 Sep 21. Review.


Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol.

Dopico AM, Bukiya AN, Singh AK.

Pharmacol Ther. 2012 Aug;135(2):133-50. doi: 10.1016/j.pharmthera.2012.05.002. Epub 2012 May 11. Review.


Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel.

Yuan P, Leonetti MD, Hsiung Y, MacKinnon R.

Nature. 2011 Dec 4;481(7379):94-7. doi: 10.1038/nature10670.


Role of the KcsA channel cytoplasmic domain in pH-dependent gating.

Hirano M, Onishi Y, Yanagida T, Ide T.

Biophys J. 2011 Nov 2;101(9):2157-62. doi: 10.1016/j.bpj.2011.09.024. Epub 2011 Nov 1.


Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain.

Pau VP, Smith FJ, Taylor AB, Parfenova LV, Samakai E, Callaghan MM, Abarca-Heidemann K, Hart PJ, Rothberg BS.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17684-9. doi: 10.1073/pnas.1107229108. Epub 2011 Oct 12.


C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.

Wang S, Chuang HH.

J Biol Chem. 2011 Nov 25;286(47):40601-7. doi: 10.1074/jbc.M111.256669. Epub 2011 Sep 16.


Crucial points within the pore as determinants of K⁺ channel conductance and gating.

Shi N, Zeng W, Ye S, Li Y, Jiang Y.

J Mol Biol. 2011 Aug 5;411(1):27-35. doi: 10.1016/j.jmb.2011.04.058. Epub 2011 Apr 30.

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