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Items: 15


Targeting iron metabolism in drug discovery and delivery.

Crielaard BJ, Lammers T, Rivella S.

Nat Rev Drug Discov. 2017 Jun;16(6):400-423. doi: 10.1038/nrd.2016.248. Epub 2017 Feb 3. Review.


Regulation of divalent metal transporter-1 by serine phosphorylation.

Seo YA, Kumara R, Wetli H, Wessling-Resnick M.

Biochem J. 2016 Nov 15;473(22):4243-4254. Epub 2016 Sep 28.


Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry.

Panda D, Rose PP, Hanna SL, Gold B, Hopkins KC, Lyde RB, Marks MS, Cherry S.

Cell Rep. 2013 Dec 26;5(6):1737-48. doi: 10.1016/j.celrep.2013.11.028. Epub 2013 Dec 12.


Iron uptake in quiescent and inflammation-activated astrocytes: a potentially neuroprotective control of iron burden.

Pelizzoni I, Zacchetti D, Campanella A, Grohovaz F, Codazzi F.

Biochim Biophys Acta. 2013 Aug;1832(8):1326-33. doi: 10.1016/j.bbadis.2013.04.007. Epub 2013 Apr 11.


ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders.

Nam H, Wang CY, Zhang L, Zhang W, Hojyo S, Fukada T, Knutson MD.

Haematologica. 2013 Jul;98(7):1049-57. doi: 10.3324/haematol.2012.072314. Epub 2013 Jan 24.


Pharmacology of iron transport.

Byrne SL, Krishnamurthy D, Wessling-Resnick M.

Annu Rev Pharmacol Toxicol. 2013;53:17-36. doi: 10.1146/annurev-pharmtox-010611-134648. Epub 2012 Sep 27. Review.


Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress.

Avila DS, Benedetto A, Au C, Manarin F, Erikson K, Soares FA, Rocha JB, Aschner M.

Free Radic Biol Med. 2012 May 1;52(9):1903-10. doi: 10.1016/j.freeradbiomed.2012.02.044. Epub 2012 Mar 8.


Anticancer activity of the iron facilitator LS081.

Li Z, Tanaka H, Galiano F, Glass J.

J Exp Clin Cancer Res. 2011 Mar 31;30:34. doi: 10.1186/1756-9966-30-34.


Human iron transporters.

Garrick MD.

Genes Nutr. 2011 Feb;6(1):45-54. doi: 10.1007/s12263-010-0184-8. Epub 2010 Sep 14.


Ebselen is a potent non-competitive inhibitor of extracellular nucleoside diphosphokinase.

Semianrio-Vidal L, van Hesuden C, Mugesh G, Lazarowski ER.

Purinergic Signal. 2010 Dec;6(4):383-91. doi: 10.1007/s11302-010-9203-x. Epub 2010 Nov 3.


ZRT/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin.

Zhao N, Gao J, Enns CA, Knutson MD.

J Biol Chem. 2010 Oct 15;285(42):32141-50. doi: 10.1074/jbc.M110.143248. Epub 2010 Aug 3.


Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

Howitt J, Putz U, Lackovic J, Doan A, Dorstyn L, Cheng H, Yang B, Chan-Ling T, Silke J, Kumar S, Tan SS.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15489-94. doi: 10.1073/pnas.0904880106. Epub 2009 Aug 25.


Small molecule inhibitors of divalent metal transporter-1.

Buckett PD, Wessling-Resnick M.

Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G798-804. doi: 10.1152/ajpgi.90342.2008. Epub 2009 Jan 29.


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