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Items: 1 to 20 of 119


Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.

Caldieri G, Barbieri E, Nappo G, Raimondi A, Bonora M, Conte A, Verhoef LGGC, Confalonieri S, Malabarba MG, Bianchi F, Cuomo A, Bonaldi T, Martini E, Mazza D, Pinton P, Tacchetti C, Polo S, Di Fiore PP, Sigismund S.

Science. 2017 May 12;356(6338):617-624. doi: 10.1126/science.aah6152.


SNPs in microRNA target sites and their potential role in human disease.

Moszyńska A, Gebert M, Collawn JF, Bartoszewski R.

Open Biol. 2017 Apr;7(4). pii: 170019. doi: 10.1098/rsob.170019. Review.


Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.

Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S244-S262. doi: 10.1074/mcp.O116.063487. Epub 2017 Feb 7.


MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.

Gutierrez KD, Davis MA, Daniels BP, Olsen TM, Ralli-Jain P, Tait SW, Gale M Jr, Oberst A.

J Immunol. 2017 Mar 1;198(5):2156-2164. doi: 10.4049/jimmunol.1601757. Epub 2017 Jan 27.


Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.

Qiang G, Whang Kong H, Gil V, Liew CW.

Sci Rep. 2017 Jan 9;7:40215. doi: 10.1038/srep40215.


Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells.

Benabdellah K, Muñoz P, Cobo M, Gutierrez-Guerrero A, Sánchez-Hernández S, Garcia-Perez A, Anderson P, Carrillo-Gálvez AB, Toscano MG, Martin F.

Sci Rep. 2016 Nov 17;6:37289. doi: 10.1038/srep37289.


The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.

Li B, Reddy S, Comai L.

Mol Cell Biol. 2017 Jan 19;37(3). pii: e00560-16. doi: 10.1128/MCB.00560-16. Print 2017 Feb 1.


A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists.

Carpentier KS, Esparo NM, Child SJ, Geballe AP.

PLoS Pathog. 2016 Oct 25;12(10):e1005966. doi: 10.1371/journal.ppat.1005966. eCollection 2016 Oct.


c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer.

Maina PK, Shao P, Liu Q, Fazli L, Tyler S, Nasir M, Dong X, Qi HH.

Oncotarget. 2016 Nov 15;7(46):75585-75602. doi: 10.18632/oncotarget.12310.


MicroRNA-433 Dampens Glucocorticoid Receptor Signaling, Impacting Circadian Rhythm and Osteoblastic Gene Expression.

Smith SS, Dole NS, Franceschetti T, Hrdlicka HC, Delany AM.

J Biol Chem. 2016 Oct 7;291(41):21717-21728. Epub 2016 Aug 22.


Distinct isoform-specific complexes of TANGO1 cooperatively facilitate collagen secretion from the endoplasmic reticulum.

Maeda M, Saito K, Katada T.

Mol Biol Cell. 2016 Sep 1;27(17):2688-96. doi: 10.1091/mbc.E16-03-0196. Epub 2016 Jul 13.


TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors.

Chitforoushzadeh Z, Ye Z, Sheng Z, LaRue S, Fry RC, Lauffenburger DA, Janes KA.

Sci Signal. 2016 Jun 7;9(431):ra59. doi: 10.1126/scisignal.aad3373.


Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).

Gambari R, Brognara E, Spandidos DA, Fabbri E.

Int J Oncol. 2016 Jul;49(1):5-32. doi: 10.3892/ijo.2016.3503. Epub 2016 May 4. Review.


c-MYC inhibition impairs hypoxia response in glioblastoma multiforme.

Mongiardi MP, Savino M, Falchetti ML, Illi B, Bozzo F, Valle C, Helmer-Citterich M, Ferrè F, Nasi S, Levi A.

Oncotarget. 2016 May 31;7(22):33257-71. doi: 10.18632/oncotarget.8921.


The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation.

Qiang G, Kong HW, Fang D, McCann M, Yang X, Du G, Blüher M, Zhu J, Liew CW.

Nat Commun. 2016 Apr 25;7:11378. doi: 10.1038/ncomms11378.


Synthetic mechanobiology: engineering cellular force generation and signaling.

Hughes JH, Kumar S.

Curr Opin Biotechnol. 2016 Aug;40:82-9. doi: 10.1016/j.copbio.2016.03.004. Epub 2016 Mar 26. Review.


Bidirectional promoters link cAMP signaling with irreversible differentiation through promoter-associated non-coding RNA (pancRNA) expression in PC12 cells.

Yamamoto N, Agata K, Nakashima K, Imamura T.

Nucleic Acids Res. 2016 Jun 20;44(11):5105-22. doi: 10.1093/nar/gkw113. Epub 2016 Mar 4.


APOBEC3A damages the cellular genome during DNA replication.

Green AM, Landry S, Budagyan K, Avgousti DC, Shalhout S, Bhagwat AS, Weitzman MD.

Cell Cycle. 2016;15(7):998-1008. doi: 10.1080/15384101.2016.1152426.


RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.

Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, Li Z, Schones DE, Frenkel B.

Nat Commun. 2016 Feb 26;7:10751. doi: 10.1038/ncomms10751.


Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.

Groeneveld MP, Brierley GV, Rocha NM, Siddle K, Semple RK.

Sci Rep. 2016 Feb 18;6:21105. doi: 10.1038/srep21105.

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