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Items: 1 to 20 of 21


Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins.

Castello A, Hentze MW, Preiss T.

Trends Endocrinol Metab. 2015 Dec;26(12):746-57. doi: 10.1016/j.tem.2015.09.012. Epub 2015 Oct 28. Review.


Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins.

Ghosh MC, Zhang DL, Rouault TA.

Neurobiol Dis. 2015 Sep;81:66-75. doi: 10.1016/j.nbd.2015.02.026. Epub 2015 Mar 11. Review.


The IRP/IRE system in vivo: insights from mouse models.

Wilkinson N, Pantopoulos K.

Front Pharmacol. 2014 Jul 28;5:176. doi: 10.3389/fphar.2014.00176. eCollection 2014. Review.


The physiological functions of iron regulatory proteins in iron homeostasis - an update.

Zhang DL, Ghosh MC, Rouault TA.

Front Pharmacol. 2014 Jun 13;5:124. doi: 10.3389/fphar.2014.00124. eCollection 2014. Review.


Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.

Zumbrennen-Bullough KB, Becker L, Garrett L, Hölter SM, Calzada-Wack J, Mossbrugger I, Quintanilla-Fend L, Racz I, Rathkolb B, Klopstock T, Wurst W, Zimmer A, Wolf E, Fuchs H, Gailus-Durner V, de Angelis MH, Romney SJ, Leibold EA.

PLoS One. 2014 Jun 4;9(6):e98072. doi: 10.1371/journal.pone.0098072. eCollection 2014.


IRP2 regulates breast tumor growth.

Wang W, Deng Z, Hatcher H, Miller LD, Di X, Tesfay L, Sui G, D'Agostino RB Jr, Torti FM, Torti SV.

Cancer Res. 2014 Jan 15;74(2):497-507. doi: 10.1158/0008-5472.CAN-13-1224. Epub 2013 Nov 27.


Mammalian iron metabolism and its control by iron regulatory proteins.

Anderson CP, Shen M, Eisenstein RS, Leibold EA.

Biochim Biophys Acta. 2012 Sep;1823(9):1468-83. doi: 10.1016/j.bbamcr.2012.05.010. Epub 2012 May 17. Review.


Regulation of cellular iron metabolism.

Wang J, Pantopoulos K.

Biochem J. 2011 Mar 15;434(3):365-81. doi: 10.1042/BJ20101825. Review.


Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1.

Cho HH, Cahill CM, Vanderburg CR, Scherzer CR, Wang B, Huang X, Rogers JT.

J Biol Chem. 2010 Oct 8;285(41):31217-32. doi: 10.1074/jbc.M110.149161. Epub 2010 Jun 17.


Iron regulatory protein-2 knockout increases perihematomal ferritin expression and cell viability after intracerebral hemorrhage.

Chen M, Awe OO, Chen-Roetling J, Regan RF.

Brain Res. 2010 Jun 14;1337:95-103. doi: 10.1016/j.brainres.2010.04.018. Epub 2010 Apr 24.


Living with iron (and oxygen): questions and answers about iron homeostasis.

Theil EC, Goss DJ.

Chem Rev. 2009 Oct;109(10):4568-79. doi: 10.1021/cr900052g. Review. No abstract available.


Iron regulatory protein 2 is involved in brain copper homeostasis.

Mueller C, Magaki S, Schrag M, Ghosh MC, Kirsch WM.

J Alzheimers Dis. 2009;18(1):201-10. doi: 10.3233/JAD-2009-1136.


Cysteine oxidation regulates the RNA-binding activity of iron regulatory protein 2.

Zumbrennen KB, Wallander ML, Romney SJ, Leibold EA.

Mol Cell Biol. 2009 Apr;29(8):2219-29. doi: 10.1128/MCB.00004-09. Epub 2009 Feb 17.


Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice.

Ghosh MC, Tong WH, Zhang D, Ollivierre-Wilson H, Singh A, Krishna MC, Mitchell JB, Rouault TA.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12028-33. doi: 10.1073/pnas.0805361105. Epub 2008 Aug 6.


Forging a field: the golden age of iron biology.

Andrews NC.

Blood. 2008 Jul 15;112(2):219-30. doi: 10.1182/blood-2007-12-077388. Review. No abstract available.


Iron-regulatory proteins: molecular biology and pathophysiological implications.

Cairo G, Recalcati S.

Expert Rev Mol Med. 2007 Dec 5;9(33):1-13. Review.


HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells.

Zumbrennen KB, Hanson ES, Leibold EA.

Biochim Biophys Acta. 2008 Feb;1783(2):246-52. Epub 2007 Aug 9.


Human iron regulatory protein 2 is easily cleaved in its specific domain: consequences for the haem binding properties of the protein.

Dycke C, Bougault C, Gaillard J, Andrieu JP, Pantopoulos K, Moulis JM.

Biochem J. 2007 Dec 15;408(3):429-39.


Homeostatic mechanisms for iron storage revealed by genetic manipulations and live imaging of Drosophila ferritin.

Missirlis F, Kosmidis S, Brody T, Mavrakis M, Holmberg S, Odenwald WF, Skoulakis EM, Rouault TA.

Genetics. 2007 Sep;177(1):89-100. Epub 2007 Jul 1.


Regional dissection and determination of loosely bound and non-heme iron in the developing mouse brain.

Magaki S, Mueller C, Yellon SM, Fox J, Kim J, Snissarenko E, Chin V, Ghosh MC, Kirsch WM.

Brain Res. 2007 Jul 16;1158:144-50. Epub 2007 May 8.

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