Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 126


Formononetin inhibits lipopolysaccharide-induced release of high mobility group box 1 by upregulating SIRT1 in a PPARδ-dependent manner.

Hwang JS, Kang ES, Han SG, Lim DS, Paek KS, Lee CH, Seo HG.

PeerJ. 2018 Jan 3;6:e4208. doi: 10.7717/peerj.4208. eCollection 2018.


p53 inhibits the upregulation of sirtuin 1 expression induced by c-Myc.

Yuan F, Liu L, Lei Y, Tang P.

Oncol Lett. 2017 Oct;14(4):4396-4402. doi: 10.3892/ol.2017.6661. Epub 2017 Jul 24.


Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling.

Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Lin HC, Hsieh PL, Tsai KL.

Redox Biol. 2018 Apr;14:116-125. doi: 10.1016/j.redox.2017.08.016. Epub 2017 Aug 24.


miR-22 suppresses tumorigenesis and improves radiosensitivity of breast cancer cells by targeting Sirt1.

Zhang X, Li Y, Wang D, Wei X.

Biol Res. 2017 Sep 7;50(1):27. doi: 10.1186/s40659-017-0133-8.


Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans.

Sangaletti R, D'Amico M, Grant J, Della-Morte D, Bianchi L.

PLoS Genet. 2017 Aug 18;13(8):e1006965. doi: 10.1371/journal.pgen.1006965. eCollection 2017 Aug.


The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts.

Vélez-Cruz R, Johnson DG.

Int J Mol Sci. 2017 Aug 16;18(8). pii: E1776. doi: 10.3390/ijms18081776. Review.


Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability.

Utani K, Fu H, Jang SM, Marks AB, Smith OK, Zhang Y, Redon CE, Shimizu N, Aladjem MI.

Nucleic Acids Res. 2017 Jul 27;45(13):7807-7824. doi: 10.1093/nar/gkx468.


miR-138 suppresses the proliferation, metastasis and autophagy of non-small cell lung cancer by targeting Sirt1.

Ye Z, Fang B, Pan J, Zhang N, Huang J, Xie C, Lou T, Cao Z.

Oncol Rep. 2017 Jun;37(6):3244-3252. doi: 10.3892/or.2017.5619. Epub 2017 May 3.


Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W.

Sci Signal. 2017 Feb 14;10(466). pii: eaai8026. doi: 10.1126/scisignal.aai8026.


Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage.

Cao X, Li C, Xiao S, Tang Y, Huang J, Zhao S, Li X, Li J, Zhang R, Yu W.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):687-692. doi: 10.1073/pnas.1608488114. Epub 2017 Jan 9.


Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding.

Park EY, Woo Y, Kim SJ, Kim DH, Lee EK, De U, Kim KS, Lee J, Jung JH, Ha KT, Choi WS, Kim IS, Lee BM, Yoon S, Moon HR, Kim HS.

Int J Biol Sci. 2016 Dec 6;12(12):1555-1567. eCollection 2016.


CHFR negatively regulates SIRT1 activity upon oxidative stress.

Kim M, Kwon YE, Song JO, Bae SJ, Seol JH.

Sci Rep. 2016 Nov 24;6:37578. doi: 10.1038/srep37578.


Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma.

Chen L, Kurtyka CA, Welsh EA, Rivera JI, Engel BE, Muñoz-Antonia T, Yoder SJ, Eschrich SA, Creelan BC, Chiappori AA, Gray JE, Ramirez JL, Rosell R, Schabath MB, Haura EB, Chen DT, Cress WD.

Oncotarget. 2016 Dec 13;7(50):82254-82265. doi: 10.18632/oncotarget.12672.


The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis.

Kitada M, Ogura Y, Koya D.

Aging (Albany NY). 2016 Oct 15;8(10):2290-2307. doi: 10.18632/aging.101068. Review.


SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells.

He M, Yuan H, Tan B, Bai R, Kim HS, Bae S, Che L, Kim JS, Gao SJ.

Oncotarget. 2016 Nov 15;7(46):75698-75711. doi: 10.18632/oncotarget.12359.


Understanding Genetic Heterogeneity in Type 2 Diabetes by Delineating Physiological Phenotypes: SIRT1 and its Gene Network in Impaired Insulin Secretion.

Ali S, Nafis S, Kalaiarasan P, Rai E, Sharma S, Bamezai RN.

Rev Diabet Stud. 2016 Spring;13(1):17-34. doi: 10.1900/RDS.2016.13.17. Epub 2016 May 10. Review.


Mitochondrial function in hypoxic ischemic injury and influence of aging.

Ham PB 3rd, Raju R.

Prog Neurobiol. 2017 Oct;157:92-116. doi: 10.1016/j.pneurobio.2016.06.006. Epub 2016 Jun 16. Review.


Expression of FOXM1 and related proteins in breast cancer molecular subtypes.

Lee JJ, Lee HJ, Son BH, Kim SB, Ahn JH, Ahn SD, Cho EY, Gong G.

Int J Exp Pathol. 2016 Apr;97(2):170-7. doi: 10.1111/iep.12187. Epub 2016 Jun 9.


Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.

Koga T, Suico MA, Shimasaki S, Watanabe E, Kai Y, Koyama K, Omachi K, Morino-Koga S, Sato T, Shuto T, Mori K, Hino S, Nakao M, Kai H.

J Biol Chem. 2015 Dec 18;290(51):30366-74. doi: 10.1074/jbc.M115.664169. Epub 2015 Oct 23.

Supplemental Content

Support Center