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Items: 13


An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila.

Grant P, Maga T, Loshakov A, Singhal R, Wali A, Nwankwo J, Baron K, Johnson D.

G3 (Bethesda). 2016 Oct 13;6(10):3185-3196. doi: 10.1534/g3.116.032508.


Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification.

Li DL, Wang ZV, Ding G, Tan W, Luo X, Criollo A, Xie M, Jiang N, May H, Kyrychenko V, Schneider JW, Gillette TG, Hill JA.

Circulation. 2016 Apr 26;133(17):1668-87. doi: 10.1161/CIRCULATIONAHA.115.017443.


The contribution of Candida albicans vacuolar ATPase subunit V₁B, encoded by VMA2, to stress response, autophagy, and virulence is independent of environmental pH.

Rane HS, Bernardo SM, Hayek SR, Binder JL, Parra KJ, Lee SA.

Eukaryot Cell. 2014 Sep;13(9):1207-21. doi: 10.1128/EC.00135-14.


Candida albicans VMA3 is necessary for V-ATPase assembly and function and contributes to secretion and filamentation.

Rane HS, Bernardo SM, Raines SM, Binder JL, Parra KJ, Lee SA.

Eukaryot Cell. 2013 Oct;12(10):1369-82. doi: 10.1128/EC.00118-13.


Deletion of vacuolar proton-translocating ATPase V(o)a isoforms clarifies the role of vacuolar pH as a determinant of virulence-associated traits in Candida albicans.

Raines SM, Rane HS, Bernardo SM, Binder JL, Lee SA, Parra KJ.

J Biol Chem. 2013 Mar 1;288(9):6190-201. doi: 10.1074/jbc.M112.426197.


Inhibitors of V-ATPase proton transport reveal uncoupling functions of tether linking cytosolic and membrane domains of V0 subunit a (Vph1p).

Chan CY, Prudom C, Raines SM, Charkhzarrin S, Melman SD, De Haro LP, Allen C, Lee SA, Sklar LA, Parra KJ.

J Biol Chem. 2012 Mar 23;287(13):10236-50. doi: 10.1074/jbc.M111.321133.


Regulation and isoform function of the V-ATPases.

Toei M, Saum R, Forgac M.

Biochemistry. 2010 Jun 15;49(23):4715-23. doi: 10.1021/bi100397s. Review.


Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry.

Johnson RM, Allen C, Melman SD, Waller A, Young SM, Sklar LA, Parra KJ.

Anal Biochem. 2010 Mar 15;398(2):203-11. doi: 10.1016/j.ab.2009.12.020.


The tether connecting cytosolic (N terminus) and membrane (C terminus) domains of yeast V-ATPase subunit a (Vph1) is required for assembly of V0 subunit d.

Ediger B, Melman SD, Pappas DL Jr, Finch M, Applen J, Parra KJ.

J Biol Chem. 2009 Jul 17;284(29):19522-32. doi: 10.1074/jbc.M109.013375.


The d subunit plays a central role in human vacuolar H(+)-ATPases.

Smith AN, Francis RW, Sorrell SL, Karet FE.

J Bioenerg Biomembr. 2008 Aug;40(4):371-80. doi: 10.1007/s10863-008-9161-y.


Function, structure and regulation of the vacuolar (H+)-ATPases.

Jefferies KC, Cipriano DJ, Forgac M.

Arch Biochem Biophys. 2008 Aug 1;476(1):33-42. doi: 10.1016/ Review.

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