Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 160


Redundant and Antagonistic Roles of XTP3B and OS9 in Decoding Glycan and Non-glycan Degrons in ER-Associated Degradation.

van der Goot AT, Pearce MMP, Leto DE, Shaler TA, Kopito RR.

Mol Cell. 2018 May 3;70(3):516-530.e6. doi: 10.1016/j.molcel.2018.03.026. Epub 2018 Apr 26.


Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation.

Preston GM, Guerriero CJ, Metzger MB, Michaelis S, Brodsky JL.

Mol Cell. 2018 Apr 19;70(2):242-253.e6. doi: 10.1016/j.molcel.2018.03.016.


Unfolded Protein Response of the Endoplasmic Reticulum in Tumor Progression and Immunogenicity.

Yoo YS, Han HG, Jeon YJ.

Oxid Med Cell Longev. 2017;2017:2969271. doi: 10.1155/2017/2969271. Epub 2017 Dec 21. Review.


Sphingolipids activate the endoplasmic reticulum stress surveillance pathway.

Piña F, Yagisawa F, Obara K, Gregerson JD, Kihara A, Niwa M.

J Cell Biol. 2018 Feb 5;217(2):495-505. doi: 10.1083/jcb.201708068. Epub 2018 Jan 9.


HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.

Wang WF, Yan L, Liu Z, Liu LX, Lin J, Liu ZY, Chen XP, Zhang W, Xu ZZ, Shi T, Li JM, Zhao YL, Meng G, Xia Y, Li JY, Zhu J.

Nat Commun. 2017 Aug 25;8(1):363. doi: 10.1038/s41467-017-00476-w.


Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.

Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M.

Nature. 2017 Aug 17;548(7667):352-355. doi: 10.1038/nature23314. Epub 2017 Jul 6.


EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila.

Sekiya M, Maruko-Otake A, Hearn S, Sakakibara Y, Fujisaki N, Suzuki E, Ando K, Iijima KM.

Dev Cell. 2017 Jun 19;41(6):652-664.e5. doi: 10.1016/j.devcel.2017.05.019.


Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates.

Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL.

Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. doi: 10.1091/mbc.E17-03-0184. Epub 2017 May 24.


Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1.

Hwang J, Walczak CP, Shaler TA, Olzmann JA, Zhang L, Elias JE, Kopito RR.

J Biol Chem. 2017 Jun 2;292(22):9104-9116. doi: 10.1074/jbc.M117.785055. Epub 2017 Apr 14.


The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.

Preston GM, Brodsky JL.

Biochem J. 2017 Feb 15;474(4):445-469. doi: 10.1042/BCJ20160582. Review.


The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein.

van de Weijer ML, van Muijlwijk GH, Visser LJ, Costa AI, Wiertz EJ, Lebbink RJ.

Viruses. 2016 Nov 15;8(11). pii: E309.


Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.

Lehrbach NJ, Ruvkun G.

Elife. 2016 Aug 16;5. pii: e17721. doi: 10.7554/eLife.17721.


The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.

Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, Gao B, Melo-Cardenas J, Zhang B, Zhang J, Song J, Zhang DD, Zhang J, Fan Y, Li H, Fang D.

Nat Commun. 2016 Jul 15;7:12073. doi: 10.1038/ncomms12073.


Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation.

Liu YC, Fujimori DG, Weissman JS.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):E4015-24. doi: 10.1073/pnas.1608795113. Epub 2016 Jun 28.


Spatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10.

Ruggiano A, Mora G, Buxó L, Carvalho P.

EMBO J. 2016 Aug 1;35(15):1644-55. doi: 10.15252/embj.201593106. Epub 2016 Jun 29.


Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.

Baldridge RD, Rapoport TA.

Cell. 2016 Jul 14;166(2):394-407. doi: 10.1016/j.cell.2016.05.048. Epub 2016 Jun 16.


Direct and essential function for Hrd3 in ER-associated degradation.

Vashistha N, Neal SE, Singh A, Carroll SM, Hampton RY.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5934-9. doi: 10.1073/pnas.1603079113. Epub 2016 May 11.


Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway.

Jeong H, Sim HJ, Song EK, Lee H, Ha SC, Jun Y, Park TJ, Lee C.

Sci Rep. 2016 Feb 9;6:20261. doi: 10.1038/srep20261.


A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.

Pfeiffer A, Stephanowitz H, Krause E, Volkwein C, Hirsch C, Jarosch E, Sommer T.

J Biol Chem. 2016 Jun 3;291(23):12195-207. doi: 10.1074/jbc.M115.703256. Epub 2016 Apr 6.


The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients.

Inoue T, Tsai B.

Mol Biol Cell. 2016 May 15;27(10):1650-62. doi: 10.1091/mbc.E16-01-0033. Epub 2016 Mar 30.

Supplemental Content

Support Center