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Items: 1 to 20 of 396

1.

System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia.

Li R, Wang Y, Cheng H, Liu G, Cheng T, Liu Y, Liu L.

BMC Syst Biol. 2017 Oct 3;11(Suppl 5):91. doi: 10.1186/s12918-017-0467-4.

2.

The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis.

Yang L, Liu L, Gao H, Pinnamaneni JP, Sanagasetti D, Singh VP, Wang K, Mathison M, Zhang Q, Chen F, Mo Q, Rosengart T, Yang J.

J Hematol Oncol. 2017 Oct 3;10(1):159. doi: 10.1186/s13045-017-0531-y.

3.

lncRNA requirements for mouse acute myeloid leukemia and normal differentiation.

Delás MJ, Sabin LR, Dolzhenko E, Knott SR, Munera Maravilla E, Jackson BT, Wild SA, Kovacevic T, Stork EM, Zhou M, Erard N, Lee E, Kelley DR, Roth M, Barbosa ISA, Zuber J, Rinn JL, Smith AD, Hannon GJ.

Elife. 2017 Sep 6;6. pii: e25607. doi: 10.7554/eLife.25607.

4.

An Integrative multi-lineage model of variation in leukopoiesis and acute myelogenous leukemia.

Sarker JM, Pearce SM, Nelson RP Jr, Kinzer-Ursem TL, Umulis DM, Rundell AE.

BMC Syst Biol. 2017 Aug 25;11(1):78. doi: 10.1186/s12918-017-0469-2.

5.

Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy.

Perna F, Sadelain M.

Transl Cancer Res. 2016 Aug;5(Suppl 2):S221-S225. doi: 10.21037/tcr.2016.08.15. No abstract available.

6.

The non-coding RNA landscape of human hematopoiesis and leukemia.

Schwarzer A, Emmrich S, Schmidt F, Beck D, Ng M, Reimer C, Adams FF, Grasedieck S, Witte D, Käbler S, Wong JWH, Shah A, Huang Y, Jammal R, Maroz A, Jongen-Lavrencic M, Schambach A, Kuchenbauer F, Pimanda JE, Reinhardt D, Heckl D, Klusmann JH.

Nat Commun. 2017 Aug 9;8(1):218. doi: 10.1038/s41467-017-00212-4.

7.

miR-99 regulates normal and malignant hematopoietic stem cell self-renewal.

Khalaj M, Woolthuis CM, Hu W, Durham BH, Chu SH, Qamar S, Armstrong SA, Park CY.

J Exp Med. 2017 Jul 21. pii: jem.20161595. doi: 10.1084/jem.20161595. [Epub ahead of print]

PMID:
28733386
8.

Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity.

Wainwright EN, Scaffidi P.

Trends Cancer. 2017 May;3(5):372-386. doi: 10.1016/j.trecan.2017.04.004. Epub 2017 May 5. Review.

9.

Emerging roles of transit-amplifying cells in tissue regeneration and cancer.

Zhang B, Hsu YC.

Wiley Interdiscip Rev Dev Biol. 2017 Sep;6(5). doi: 10.1002/wdev.282. Epub 2017 Jul 3. Review.

PMID:
28670819
10.

The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.

Lin S, Luo RT, Shrestha M, Thirman MJ, Mulloy JC.

Blood. 2017 Aug 17;130(7):903-907. doi: 10.1182/blood-2017-04-777185. Epub 2017 Jun 21.

11.

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.

Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR.

Sci Adv. 2017 Jun 16;3(6):e1700341. doi: 10.1126/sciadv.1700341. eCollection 2017 Jun.

12.

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.

Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ.

Blood. 2017 Aug 3;130(5):619-624. doi: 10.1182/blood-2016-09-738591. Epub 2017 Jun 14.

PMID:
28615219
13.

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.

Chen Y, Anastassiadis K, Kranz A, Stewart AF, Arndt K, Waskow C, Yokoyama A, Jones K, Neff T, Lee Y, Ernst P.

Cancer Cell. 2017 Jun 12;31(6):755-770.e6. doi: 10.1016/j.ccell.2017.05.002.

PMID:
28609655
14.

EMP2 is a novel therapeutic target for endometrial cancer stem cells.

Kiyohara MH, Dillard C, Tsui J, Kim SR, Lu J, Sachdev D, Goodglick L, Tong M, Torous VF, Aryasomayajula C, Wang W, Najafzadeh P, Gordon LK, Braun J, McDermott S, Wicha MS, Wadehra M.

Oncogene. 2017 Oct 19;36(42):5793-5807. doi: 10.1038/onc.2017.142. Epub 2017 Jun 12.

PMID:
28604744
15.

Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity.

Matte-Martone C, Liu J, Zhou M, Chikina M, Green DR, Harty JT, Shlomchik WD.

J Clin Invest. 2017 Jun 30;127(7):2765-2776. doi: 10.1172/JCI85736. Epub 2017 Jun 12.

16.

Biliary tract cancer stem cells - translational options and challenges.

Mayr C, Ocker M, Ritter M, Pichler M, Neureiter D, Kiesslich T.

World J Gastroenterol. 2017 Apr 14;23(14):2470-2482. doi: 10.3748/wjg.v23.i14.2470. Review.

17.

Dysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia.

Basilico S, Göttgens B.

J Mol Med (Berl). 2017 Jul;95(7):719-727. doi: 10.1007/s00109-017-1535-3. Epub 2017 Apr 20. Review.

18.

Clustering by fast search and merge of local density peaks for gene expression microarray data.

Mehmood R, El-Ashram S, Bie R, Dawood H, Kos A.

Sci Rep. 2017 Apr 19;7:45602. doi: 10.1038/srep45602.

19.

Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.

Okuda H, Stanojevic B, Kanai A, Kawamura T, Takahashi S, Matsui H, Takaori-Kondo A, Yokoyama A.

J Clin Invest. 2017 May 1;127(5):1918-1931. doi: 10.1172/JCI91406. Epub 2017 Apr 10.

20.

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E.

Nature. 2017 Apr 6;544(7648):53-58. doi: 10.1038/nature21693. Epub 2017 Mar 29.

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