Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 21


Variants of sequence family B Thermococcus kodakaraensis DNA polymerase with increased mismatch extension selectivity.

Huber C, Marx A.

PLoS One. 2017 Aug 23;12(8):e0183623. doi: 10.1371/journal.pone.0183623. eCollection 2017.


Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.

Houlihan G, Arangundy-Franklin S, Holliger P.

Acc Chem Res. 2017 Apr 18;50(4):1079-1087. doi: 10.1021/acs.accounts.7b00056. Epub 2017 Apr 6.


Evolution of thermophilic DNA polymerases for the recognition and amplification of C2'-modified DNA.

Chen T, Hongdilokkul N, Liu Z, Adhikary R, Tsuen SS, Romesberg FE.

Nat Chem. 2016 Jun;8(6):556-62. doi: 10.1038/nchem.2493. Epub 2016 Apr 18.


Modified Nucleoside Triphosphates for In-vitro Selection Techniques.

Dellafiore MA, Montserrat JM, Iribarren AM.

Front Chem. 2016 May 4;4:18. doi: 10.3389/fchem.2016.00018. eCollection 2016. Review.


An in vitro compartmentalization-based method for the selection of bond-forming enzymes from large libraries.

Gianella P, Snapp EL, Levy M.

Biotechnol Bioeng. 2016 Aug;113(8):1647-57. doi: 10.1002/bit.25939. Epub 2016 Feb 8.


A polymerase engineered for bisulfite sequencing.

Millar D, Christova Y, Holliger P.

Nucleic Acids Res. 2015 Dec 15;43(22):e155. doi: 10.1093/nar/gkv798. Epub 2015 Aug 13.


Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes.

Guilliam TA, Keen BA, Brissett NC, Doherty AJ.

Nucleic Acids Res. 2015 Aug 18;43(14):6651-64. doi: 10.1093/nar/gkv625. Epub 2015 Jun 24. Review.


DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides.

Laos R, Thomson JM, Benner SA.

Front Microbiol. 2014 Oct 31;5:565. doi: 10.3389/fmicb.2014.00565. eCollection 2014. Review.


Mutant Taq DNA polymerases with improved elongation ability as a useful reagent for genetic engineering.

Yamagami T, Ishino S, Kawarabayasi Y, Ishino Y.

Front Microbiol. 2014 Sep 3;5:461. doi: 10.3389/fmicb.2014.00461. eCollection 2014.


DNA polymerases as useful reagents for biotechnology - the history of developmental research in the field.

Ishino S, Ishino Y.

Front Microbiol. 2014 Aug 29;5:465. doi: 10.3389/fmicb.2014.00465. eCollection 2014. Review.


A highly divergent archaeo-eukaryotic primase from the Thermococcus nautilus plasmid, pTN2.

Gill S, Krupovic M, Desnoues N, Béguin P, Sezonov G, Forterre P.

Nucleic Acids Res. 2014 Apr;42(6):3707-19. doi: 10.1093/nar/gkt1385. Epub 2014 Jan 20.


Directed polymerase evolution.

Chen T, Romesberg FE.

FEBS Lett. 2014 Jan 21;588(2):219-29. doi: 10.1016/j.febslet.2013.10.040. Epub 2013 Nov 5. Review.


Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA.

Wynne SA, Pinheiro VB, Holliger P, Leslie AG.

PLoS One. 2013 Aug 5;8(8):e70892. doi: 10.1371/journal.pone.0070892. Print 2013.


A short adaptive path from DNA to RNA polymerases.

Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8067-72. doi: 10.1073/pnas.1120964109. Epub 2012 May 7.


Unlocking the sugar "steric gate" of DNA polymerases.

Brown JA, Suo Z.

Biochemistry. 2011 Feb 22;50(7):1135-42. doi: 10.1021/bi101915z. Epub 2011 Jan 26. Review.


CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.

Ramsay N, Jemth AS, Brown A, Crampton N, Dear P, Holliger P.

J Am Chem Soc. 2010 Apr 14;132(14):5096-104. doi: 10.1021/ja909180c.


Evolving a polymerase for hydrophobic base analogues.

Loakes D, Gallego J, Pinheiro VB, Kool ET, Holliger P.

J Am Chem Soc. 2009 Oct 21;131(41):14827-37. doi: 10.1021/ja9039696.


Mutants of Taq DNA polymerase resistant to PCR inhibitors allow DNA amplification from whole blood and crude soil samples.

Kermekchiev MB, Kirilova LI, Vail EE, Barnes WM.

Nucleic Acids Res. 2009 Apr;37(5):e40. doi: 10.1093/nar/gkn1055. Epub 2009 Feb 10.


Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer.

Arezi B, Hogrefe H.

Nucleic Acids Res. 2009 Feb;37(2):473-81. doi: 10.1093/nar/gkn952. Epub 2008 Dec 4.


Molecular breeding of polymerases for amplification of ancient DNA.

d'Abbadie M, Hofreiter M, Vaisman A, Loakes D, Gasparutto D, Cadet J, Woodgate R, Pääbo S, Holliger P.

Nat Biotechnol. 2007 Aug;25(8):939-43. Epub 2007 Jul 15.

Supplemental Content

Support Center