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Items: 1 to 20 of 171


Transient Receptor Potential Melastatin 2 Negatively Regulates LPS-ATP-Induced Caspase-1-Dependent Pyroptosis of Bone Marrow-Derived Macrophage by Modulating ROS Production.

Wang H, Zhou X, Li H, Qian X, Wang Y, Ma L.

Biomed Res Int. 2017;2017:2975648. doi: 10.1155/2017/2975648. Epub 2017 Nov 8.


Function and regulation of IL-1α in inflammatory diseases and cancer.

Malik A, Kanneganti TD.

Immunol Rev. 2018 Jan;281(1):124-137. doi: 10.1111/imr.12615. Review.


Cell death and cell lysis are separable events during pyroptosis.

DiPeso L, Ji DX, Vance RE, Price JV.

Cell Death Discov. 2017 Nov 13;3:17070. doi: 10.1038/cddiscovery.2017.70. eCollection 2017.


Phagocytosis of environmental or metabolic crystalline particles induces cytotoxicity by triggering necroptosis across a broad range of particle size and shape.

Honarpisheh M, Foresto-Neto O, Desai J, Steiger S, Gómez LA, Popper B, Boor P, Anders HJ, Mulay SR.

Sci Rep. 2017 Nov 14;7(1):15523. doi: 10.1038/s41598-017-15804-9.


Salmonella enterica Serovar Typhimurium Strategies for Host Adaptation.

Anderson CJ, Kendall MM.

Front Microbiol. 2017 Oct 12;8:1983. doi: 10.3389/fmicb.2017.01983. eCollection 2017. Review.


NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats.

Qiu Z, Lei S, Zhao B, Wu Y, Su W, Liu M, Meng Q, Zhou B, Leng Y, Xia ZY.

Oxid Med Cell Longev. 2017;2017:9743280. doi: 10.1155/2017/9743280. Epub 2017 Sep 14.


Inflammatory cell death in intestinal pathologies.

Sharma D, Kanneganti TD.

Immunol Rev. 2017 Nov;280(1):57-73. doi: 10.1111/imr.12602. Review.


How Inflammasomes Inform Adaptive Immunity.

Evavold CL, Kagan JC.

J Mol Biol. 2018 Jan 19;430(2):217-237. doi: 10.1016/j.jmb.2017.09.019. Epub 2017 Oct 5. Review.


Epithelial Cell Inflammasomes in Intestinal Immunity and Inflammation.

Lei-Leston AC, Murphy AG, Maloy KJ.

Front Immunol. 2017 Sep 20;8:1168. doi: 10.3389/fimmu.2017.01168. eCollection 2017. Review.


IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.

Wallet P, Benaoudia S, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovliov I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjöstedt A, Henry T.

PLoS Pathog. 2017 Oct 2;13(10):e1006630. doi: 10.1371/journal.ppat.1006630. eCollection 2017 Oct.


Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

Cecil JD, O'Brien-Simpson NM, Lenzo JC, Holden JA, Singleton W, Perez-Gonzalez A, Mansell A, Reynolds EC.

Front Immunol. 2017 Aug 25;8:1017. doi: 10.3389/fimmu.2017.01017. eCollection 2017.


Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O'Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA.

Front Cell Infect Microbiol. 2017 Aug 4;7:351. doi: 10.3389/fcimb.2017.00351. eCollection 2017.


Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.

Mascarenhas DPA, Cerqueira DM, Pereira MSF, Castanheira FVS, Fernandes TD, Manin GZ, Cunha LD, Zamboni DS.

PLoS Pathog. 2017 Aug 3;13(8):e1006502. doi: 10.1371/journal.ppat.1006502. eCollection 2017 Aug.


AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication.

Yogarajah T, Ong KC, Perera D, Wong KT.

Sci Rep. 2017 Jul 19;7(1):5845. doi: 10.1038/s41598-017-05589-2.


Proteases Revisited: Roles and Therapeutic Implications in Fibrosis.

Kryczka J, Boncela J.

Mediators Inflamm. 2017;2017:2570154. doi: 10.1155/2017/2570154. Epub 2017 May 31. Review.


Globular Adiponectin Inhibits Lipopolysaccharide-Primed Inflammasomes Activation in Macrophages via Autophagy Induction: The Critical Role of AMPK Signaling.

Kim MJ, Kim EH, Pun NT, Chang JH, Kim JA, Jeong JH, Choi DY, Kim SH, Park PH.

Int J Mol Sci. 2017 Jun 15;18(6). pii: E1275. doi: 10.3390/ijms18061275.


The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation.

Ratsimandresy RA, Chu LH, Khare S, de Almeida L, Gangopadhyay A, Indramohan M, Misharin AV, Greaves DR, Perlman H, Dorfleutner A, Stehlik C.

Nat Commun. 2017 Jun 5;8:15556. doi: 10.1038/ncomms15556.


Dying to protect: cell death and the control of T-cell homeostasis.

Li KP, Shanmuganad S, Carroll K, Katz JD, Jordan MB, Hildeman DA.

Immunol Rev. 2017 May;277(1):21-43. doi: 10.1111/imr.12538. Review.


Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

Man SM, Karki R, Kanneganti TD.

Immunol Rev. 2017 May;277(1):61-75. doi: 10.1111/imr.12534. Review.


Mechanisms for Pseudoalteromonas piscicida-Induced Killing of Vibrios and Other Bacterial Pathogens.

Richards GP, Watson MA, Needleman DS, Uknalis J, Boyd EF, Fay JP.

Appl Environ Microbiol. 2017 May 17;83(11). pii: e00175-17. doi: 10.1128/AEM.00175-17. Print 2017 Jun 1.

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