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Items: 14


Efficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA.

Mohamadi A, Miller LW.

Tetrahedron Lett. 2017 Apr 12;58(15):1441-1444. doi: 10.1016/j.tetlet.2017.02.056. Epub 2017 Feb 20.


Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.

Zeglis BM, Houghton JL, Evans MJ, Viola-Villegas N, Lewis JS.

Inorg Chem. 2014 Feb 17;53(4):1880-99. doi: 10.1021/ic401607z. Epub 2013 Dec 6.


H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu.

Bailey GA, Price EW, Zeglis BM, Ferreira CL, Boros E, Lacasse MJ, Patrick BO, Lewis JS, Adam MJ, Orvig C.

Inorg Chem. 2012 Nov 19;51(22):12575-89. doi: 10.1021/ic302225z. Epub 2012 Oct 29.


86Y based PET radiopharmaceuticals: radiochemistry and biological applications.

Nayak TK, Brechbiel MW.

Med Chem. 2011 Sep;7(5):380-8. Review.


A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.

Zeglis BM, Lewis JS.

Dalton Trans. 2011 Jun 21;40(23):6168-95. doi: 10.1039/c0dt01595d. Epub 2011 Mar 25.


Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease.

Wadas TJ, Wong EH, Weisman GR, Anderson CJ.

Chem Rev. 2010 May 12;110(5):2858-902. doi: 10.1021/cr900325h. Review. No abstract available.


Melanoma imaging using (111)In-, (86)Y- and (68)Ga-labeled CHX-A''-Re(Arg11)CCMSH.

Wei L, Zhang X, Gallazzi F, Miao Y, Jin X, Brechbiel MW, Xu H, Clifford T, Welch MJ, Lewis JS, Quinn TP.

Nucl Med Biol. 2009 May;36(4):345-54. doi: 10.1016/j.nucmedbio.2009.01.007. Epub 2009 Mar 26.


Evaluation of a maleimido derivative of CHX-A'' DTPA for site-specific labeling of affibody molecules.

Tolmachev V, Xu H, Wållberg H, Ahlgren S, Hjertman M, Sjöberg A, Sandström M, Abrahmsén L, Brechbiel MW, Orlova A.

Bioconjug Chem. 2008 Aug;19(8):1579-87. doi: 10.1021/bc800110y. Epub 2008 Jul 12.


Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling.

Boswell CA, Regino CA, Baidoo KE, Wong KJ, Bumb A, Xu H, Milenic DE, Kelley JA, Lai CC, Brechbiel MW.

Bioconjug Chem. 2008 Jul;19(7):1476-84. doi: 10.1021/bc800039e. Epub 2008 Jul 3.


Synthesis, characterization, and biological evaluation of integrin alphavbeta3-targeted PAMAM dendrimers.

Boswell CA, Eck PK, Regino CA, Bernardo M, Wong KJ, Milenic DE, Choyke PL, Brechbiel MW.

Mol Pharm. 2008 Jul-Aug;5(4):527-39. doi: 10.1021/mp800022a. Epub 2008 Jun 7.


A novel bifunctional maleimido CHX-A'' chelator for conjugation to thiol-containing biomolecules.

Xu H, Baidoo KE, Wong KJ, Brechbiel MW.

Bioorg Med Chem Lett. 2008 Apr 15;18(8):2679-83. doi: 10.1016/j.bmcl.2008.03.022. Epub 2008 Mar 10.


Bifunctional chelates for metal nuclides.

Brechbiel MW.

Q J Nucl Med Mol Imaging. 2008 Jun;52(2):166-73. Epub 2007 Nov 28. Review.


Development of radioimmunotherapeutic and diagnostic antibodies: an inside-out view.

Boswell CA, Brechbiel MW.

Nucl Med Biol. 2007 Oct;34(7):757-78. Epub 2007 Jun 8. Review.


Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging.

Xu H, Baidoo K, Gunn AJ, Boswell CA, Milenic DE, Choyke PL, Brechbiel MW.

J Med Chem. 2007 Sep 20;50(19):4759-65. Epub 2007 Aug 29.

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