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Items: 18

1.

Association and differences in genetic polymorphisms in PCSK9 gene in subjects with lacunar infarction in the Han and Uygur populations of Xinjiang Uygur Autonomous Region of China.

Han DF, Ma JH, Hao CG, Tuerhong Tuerxun, Du L, Zhang XN.

Neural Regen Res. 2017 Aug;12(8):1315-1321. doi: 10.4103/1673-5374.213552.

2.

Atherogenesis and metabolic dysregulation in LDL receptor-knockout rats.

Sithu SD, Malovichko MV, Riggs KA, Wickramasinghe NS, Winner MG, Agarwal A, Hamed-Berair RE, Kalani A, Riggs DW, Bhatnagar A, Srivastava S.

JCI Insight. 2017 May 4;2(9). pii: 86442. doi: 10.1172/jci.insight.86442. [Epub ahead of print]

3.

Effects of LDL Receptor Modulation on Lymphatic Function.

Milasan A, Dallaire F, Mayer G, Martel C.

Sci Rep. 2016 Jun 9;6:27862. doi: 10.1038/srep27862.

4.

Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.

Tavori H, Giunzioni I, Predazzi IM, Plubell D, Shivinsky A, Miles J, Devay RM, Liang H, Rashid S, Linton MF, Fazio S.

Cardiovasc Res. 2016 May 15;110(2):268-78. doi: 10.1093/cvr/cvw053. Epub 2016 Mar 15.

5.

PCSK9 and triglyceride-rich lipoprotein metabolism.

Druce I, Abujrad H, Ooi TC.

J Biomed Res. 2015 Jul 20;29. doi: 10.7555/JBR.29.20150052. [Epub ahead of print] Review.

6.

High-fructose feeding promotes accelerated degradation of hepatic LDL receptor and hypercholesterolemia in hamsters via elevated circulating PCSK9 levels.

Dong B, Singh AB, Azhar S, Seidah NG, Liu J.

Atherosclerosis. 2015 Apr;239(2):364-74. doi: 10.1016/j.atherosclerosis.2015.01.013. Epub 2015 Jan 30.

7.

On the function and homeostasis of PCSK9: reciprocal interaction with LDLR and additional lipid effects.

Tavori H, Rashid S, Fazio S.

Atherosclerosis. 2015 Feb;238(2):264-70. doi: 10.1016/j.atherosclerosis.2014.12.017. Epub 2014 Dec 17. Review.

8.

Correlation of PCSK9 gene polymorphism with cerebral ischemic stroke in Xinjiang Han and Uygur populations.

Han D, Ma J, Zhang X, Cai J, Li J, Tuerxun T, Hao C, Du L, Lei J.

Med Sci Monit. 2014 Sep 30;20:1758-67. doi: 10.12659/MSM.892091.

9.

PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells.

Lagace TA.

Curr Opin Lipidol. 2014 Oct;25(5):387-93. doi: 10.1097/MOL.0000000000000114. Review.

10.

Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts.

Sleiman P, Bradfield J, Mentch F, Almoguera B, Connolly J, Hakonarson H.

Front Genet. 2014 Apr 29;5:105. doi: 10.3389/fgene.2014.00105. eCollection 2014.

11.

Proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism interacts with alcohol consumption to modulate serum lipid levels.

Aung LH, Yin RX, Wu DF, Cao XL, Hu XJ, Miao L.

Int J Med Sci. 2013;10(2):124-32. doi: 10.7150/ijms.5296. Epub 2012 Dec 30.

12.

Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets.

Cariou B, Langhi C, Le Bras M, Bortolotti M, Lê KA, Theytaz F, Le May C, Guyomarc'h-Delasalle B, Zaïr Y, Kreis R, Boesch C, Krempf M, Tappy L, Costet P.

Nutr Metab (Lond). 2013 Jan 8;10(1):4. doi: 10.1186/1743-7075-10-4.

13.

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters.

Wu M, Dong B, Cao A, Li H, Liu J.

Atherosclerosis. 2012 Oct;224(2):401-10. doi: 10.1016/j.atherosclerosis.2012.08.012. Epub 2012 Aug 24.

14.

The PCSK9 decade.

Lambert G, Sjouke B, Choque B, Kastelein JJ, Hovingh GK.

J Lipid Res. 2012 Dec;53(12):2515-24. doi: 10.1194/jlr.R026658. Epub 2012 Jul 17. Review.

15.

Lack of a relationship between plasma PCSK9 concentrations and hepatic lipoprotein kinetics in obese people.

Sullivan S, Fabbrini E, Horton JD, Korenblat K, Patterson BW, Klein S.

Transl Res. 2011 Nov;158(5):302-6. doi: 10.1016/j.trsl.2011.06.006. Epub 2011 Jul 19.

16.

The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations.

Aung LH, Yin RX, Miao L, Hu XJ, Yan TT, Cao XL, Wu DF, Li Q, Pan SL, Wu JZ.

Lipids Health Dis. 2011 Jan 13;10:5. doi: 10.1186/1476-511X-10-5.

17.

Inflammation stimulates the expression of PCSK9.

Feingold KR, Moser AH, Shigenaga JK, Patzek SM, Grunfeld C.

Biochem Biophys Res Commun. 2008 Sep 19;374(2):341-4. doi: 10.1016/j.bbrc.2008.07.023. Epub 2008 Jul 16.

18.

Molecular population genetics of PCSK9: a signature of recent positive selection.

Ding K, Kullo IJ.

Pharmacogenet Genomics. 2008 Mar;18(3):169-79. doi: 10.1097/FPC.0b013e3282f44d99.

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