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Items: 1 to 20 of 32


The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells.

Crane MM, Kaeberlein M.

Curr Opin Syst Biol. 2018 Apr;8:25-31. doi: 10.1016/j.coisb.2017.11.010. Epub 2017 Dec 6.


Nutritional Control of Chronological Aging and Heterochromatin in Saccharomyces cerevisiae.

McCleary DF, Rine J.

Genetics. 2017 Mar;205(3):1179-1193. doi: 10.1534/genetics.116.196485. Epub 2017 Jan 6.


Dietary restriction and lifespan: Lessons from invertebrate models.

Kapahi P, Kaeberlein M, Hansen M.

Ageing Res Rev. 2017 Oct;39:3-14. doi: 10.1016/j.arr.2016.12.005. Epub 2016 Dec 19. Review.


Mitochondrial function in hypoxic ischemic injury and influence of aging.

Ham PB 3rd, Raju R.

Prog Neurobiol. 2017 Oct;157:92-116. doi: 10.1016/j.pneurobio.2016.06.006. Epub 2016 Jun 16. Review.


Biochemical Genetic Pathways that Modulate Aging in Multiple Species.

Bitto A, Wang AM, Bennett CF, Kaeberlein M.

Cold Spring Harb Perspect Med. 2015 Nov 2;5(11). pii: a025114. doi: 10.1101/cshperspect.a025114. Review.


Sirtuin regulation in aging and injury.

Poulose N, Raju R.

Biochim Biophys Acta. 2015 Nov;1852(11):2442-55. doi: 10.1016/j.bbadis.2015.08.017. Epub 2015 Aug 21. Review.


Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.

Peng J, He MH, Duan YM, Liu YT, Zhou JQ.

PLoS Genet. 2015 Mar 30;11(3):e1005071. doi: 10.1371/journal.pgen.1005071. eCollection 2015 Mar. Erratum in: PLoS Genet. 2015 Jun;11(6):e1005313.


Sirtuins in epigenetic regulation.

Jing H, Lin H.

Chem Rev. 2015 Mar 25;115(6):2350-75. doi: 10.1021/cr500457h. Epub 2015 Jan 28. Review. No abstract available.


Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae.

Huberts DH, González J, Lee SS, Litsios A, Hubmann G, Wit EC, Heinemann M.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11727-31. doi: 10.1073/pnas.1410024111. Epub 2014 Jul 28.


The controversial world of sirtuins.

Dang W.

Drug Discov Today Technol. 2014 Jun;12:e9-e17. doi: 10.1016/j.ddtec.2012.08.003. Review.


The fine line between lifespan extension and shortening in response to caloric restriction.

Szafranski K, Mekhail K.

Nucleus. 2014 Jan-Feb;5(1):56-65. doi: 10.4161/nucl.27929. Epub 2014 Jan 27. Review.


Yeast sirtuins and the regulation of aging.

Wierman MB, Smith JS.

FEMS Yeast Res. 2014 Feb;14(1):73-88. doi: 10.1111/1567-1364.12115. Epub 2013 Nov 14. Review.


Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila.

Hoffmann J, Romey R, Fink C, Yong L, Roeder T.

Aging (Albany NY). 2013 Apr;5(4):315-27.


Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae.

Wu Z, Liu SQ, Huang D.

PLoS One. 2013 May 17;8(5):e64448. doi: 10.1371/journal.pone.0064448. Print 2013.


Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.

Delaney JR, Ahmed U, Chou A, Sim S, Carr D, Murakami CJ, Schleit J, Sutphin GL, An EH, Castanza A, Fletcher M, Higgins S, Jelic M, Klum S, Muller B, Peng ZJ, Rai D, Ros V, Singh M, Wende HV, Kennedy BK, Kaeberlein M.

Aging Cell. 2013 Feb;12(1):156-66. doi: 10.1111/acel.12032. Epub 2012 Dec 25.


Yeast as a model to understand the interaction between genotype and the response to calorie restriction.

Schleit J, Wasko BM, Kaeberlein M.

FEBS Lett. 2012 Aug 31;586(18):2868-73. doi: 10.1016/j.febslet.2012.07.038. Epub 2012 Jul 22. Review.


Replicative and chronological aging in Saccharomyces cerevisiae.

Longo VD, Shadel GS, Kaeberlein M, Kennedy B.

Cell Metab. 2012 Jul 3;16(1):18-31. doi: 10.1016/j.cmet.2012.06.002. Review.


Global heterochromatin loss: a unifying theory of aging?

Tsurumi A, Li WX.

Epigenetics. 2012 Jul;7(7):680-8. doi: 10.4161/epi.20540. Epub 2012 Jul 1.


Calorie restriction: what recent results suggest for the future of ageing research.

Smith DL Jr, Nagy TR, Allison DB.

Eur J Clin Invest. 2010 May;40(5):440-50. doi: 10.1111/j.1365-2362.2010.02276.x. Review.


Regulation of SIRT1 in cellular functions: role of polyphenols.

Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I.

Arch Biochem Biophys. 2010 Sep 1;501(1):79-90. doi: 10.1016/ Epub 2010 May 5. Review.

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