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Items: 1 to 20 of 22

1.

TNF activation of NF-κB is essential for development of single-positive thymocytes.

Webb LV, Ley SC, Seddon B.

J Exp Med. 2016 Jul 25;213(8):1399-407. doi: 10.1084/jem.20151604. Epub 2016 Jul 18.

2.

Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes.

Berner A, Bachmann M, Bender C, Pfeilschifter J, Christen U, Mühl H.

Front Pharmacol. 2016 Jan 12;6:317. doi: 10.3389/fphar.2015.00317. eCollection 2015.

3.

Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90.

Faridi U, Dhawan SS, Pal S, Gupta S, Shukla AK, Darokar MP, Sharma A, Shasany AK.

OMICS. 2016 Jan;20(1):53-64. doi: 10.1089/omi.2015.0118.

4.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.

Urban BC, Collard TJ, Eagle CJ, Southern SL, Greenhough A, Hamdollah-Zadeh M, Ghosh A, Poulsom R, Paraskeva C, Silver A, Williams AC.

Gut. 2016 Jul;65(7):1151-64. doi: 10.1136/gutjnl-2014-308270. Epub 2015 Jun 1.

5.

Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics.

Popp MW, Maquat LE.

Nat Commun. 2015 Mar 26;6:6632. doi: 10.1038/ncomms7632.

6.

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.

Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS.

Nat Commun. 2014 Dec 15;5:5798. doi: 10.1038/ncomms6798.

7.

Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.

Hutchins AP, Diez D, Miranda-Saavedra D.

JAKSTAT. 2013 Oct 1;2(4):e25097. doi: 10.4161/jkst.25097. Epub 2013 May 20. Review.

8.

The tumor promoter and NF-κB modulator Bcl-3 regulates splenic B cell development.

Zhang X, Paun A, Claudio E, Wang H, Siebenlist U.

J Immunol. 2013 Dec 15;191(12):5984-92. doi: 10.4049/jimmunol.1300611. Epub 2013 Nov 15.

9.

Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP.

Huang X, Meng B, Iqbal J, Ding BB, Perry AM, Cao W, Smith LM, Bi C, Jiang C, Greiner TC, Weisenburger DD, Rimsza L, Rosenwald A, Ott G, Delabie J, Campo E, Braziel RM, Gascoyne RD, Cook JR, Tubbs RR, Jaffe ES, Armitage JO, Vose JM, Staudt LM, McKeithan TW, Chan WC, Ye BH, Fu K.

J Clin Oncol. 2013 Dec 20;31(36):4520-8. doi: 10.1200/JCO.2012.45.6004. Epub 2013 Nov 12.

10.

Emerging therapeutic paradigms to target the dysregulated Janus kinase/signal transducer and activator of transcription pathway in hematological malignancies.

Mughal TI, Girnius S, Rosen ST, Kumar S, Wiestner A, Abdel-Wahab O, Kiladjian JJ, Wilson WH, Van Etten RA.

Leuk Lymphoma. 2014 Sep;55(9):1968-79. doi: 10.3109/10428194.2013.863307. Epub 2014 Feb 17. Review.

11.

Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance.

Bala S, Tang A, Catalano D, Petrasek J, Taha O, Kodys K, Szabo G.

J Leukoc Biol. 2012 Sep;92(3):611-20. doi: 10.1189/jlb.0112050. Epub 2012 Jul 10.

12.

A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.

Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens CM, Young DA, Isaacs JD.

Ann Rheum Dis. 2012 Aug;71(8):1374-81. doi: 10.1136/annrheumdis-2011-200968. Epub 2012 Apr 24.

13.

NF-κB, the first quarter-century: remarkable progress and outstanding questions.

Hayden MS, Ghosh S.

Genes Dev. 2012 Feb 1;26(3):203-34. doi: 10.1101/gad.183434.111. Review.

14.

Role of Bcl-3 in solid tumors.

Maldonado V, Melendez-Zajgla J.

Mol Cancer. 2011 Dec 23;10:152. doi: 10.1186/1476-4598-10-152. Review.

15.

Activation of oxidative stress-regulated Bcl-3 suppresses CTCF in corneal epithelial cells.

Wang Y, Lu L.

PLoS One. 2011;6(8):e23984. doi: 10.1371/journal.pone.0023984. Epub 2011 Aug 30.

16.

Interleukin-6 protects human macrophages from cellular cholesterol accumulation and attenuates the proinflammatory response.

Frisdal E, Lesnik P, Olivier M, Robillard P, Chapman MJ, Huby T, Guerin M, Le Goff W.

J Biol Chem. 2011 Sep 2;286(35):30926-36. doi: 10.1074/jbc.M111.264325. Epub 2011 Jul 8.

17.

Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis.

Kreisel D, Sugimoto S, Tietjens J, Zhu J, Yamamoto S, Krupnick AS, Carmody RJ, Gelman AE.

J Clin Invest. 2011 Jan;121(1):265-76. doi: 10.1172/JCI42596. Epub 2010 Dec 13.

18.

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

Marchetti S, Gamas P, Belhacène N, Grosso S, Pradelli LA, Colosetti P, Johansen C, Iversen L, Deckert M, Luciano F, Hofman P, Ortonne N, Khemis A, Mari B, Ortonne JP, Ricci JE, Auberger P.

EMBO J. 2009 Aug 19;28(16):2449-60. doi: 10.1038/emboj.2009.183. Epub 2009 Jul 9.

19.

High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis.

Brenne AT, Fagerli UM, Shaughnessy JD Jr, Våtsveen TK, Rø TB, Hella H, Zhan F, Barlogie B, Sundan A, Børset M, Waage A.

Eur J Haematol. 2009 May;82(5):354-63. doi: 10.1111/j.1600-0609.2009.01225.x. Epub 2009 Jan 13.

20.

Differential regulation of STAT family members by glycogen synthase kinase-3.

Beurel E, Jope RS.

J Biol Chem. 2008 Aug 8;283(32):21934-44. doi: 10.1074/jbc.M802481200. Epub 2008 Jun 11.

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