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Items: 1 to 20 of 72


An immunoregulatory role of dendritic cell-derived exosomes versus HIV-1 infection: take it easy but be warned.

Chistiakov DA, Grechko AV, Orekhov AN, Bobryshev YV.

Ann Transl Med. 2017 Sep;5(17):362. doi: 10.21037/atm.2017.06.34. No abstract available.


Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.

Manrique S, Sauter D, Horenkamp FA, Lülf S, Yu H, Hotter D, Anand K, Kirchhoff F, Geyer M.

Nat Commun. 2017 Sep 5;8(1):442. doi: 10.1038/s41467-017-00481-z.


Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity.

Canedo-Marroquín G, Acevedo-Acevedo O, Rey-Jurado E, Saavedra JM, Lay MK, Bueno SM, Riedel CA, Kalergis AM.

Front Cell Infect Microbiol. 2017 Aug 16;7:367. doi: 10.3389/fcimb.2017.00367. eCollection 2017. Review.


The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.

Trautz B, Wiedemann H, Lüchtenborg C, Pierini V, Kranich J, Glass B, Kräusslich HG, Brocker T, Pizzato M, Ruggieri A, Brügger B, Fackler OT.

J Biol Chem. 2017 Aug 18;292(33):13702-13713. doi: 10.1074/jbc.M117.797332. Epub 2017 Jun 28.


HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread.

Len ACL, Starling S, Shivkumar M, Jolly C.

Cell Rep. 2017 Jan 24;18(4):1062-1074. doi: 10.1016/j.celrep.2016.12.057.


HIV-1 Nef Impairs the Formation of Calcium Membrane Territories Controlling the Signaling Nanoarchitecture at the Immunological Synapse.

Silva JG, Martins NP, Henriques R, Soares H.

J Immunol. 2016 Nov 15;197(10):4042-4052. Epub 2016 Oct 19.


The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.

Trautz B, Pierini V, Wombacher R, Stolp B, Chase AJ, Pizzato M, Fackler OT.

J Virol. 2016 Nov 14;90(23):10915-10927. Print 2016 Dec 1.


HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.

Deng J, Mitsuki YY, Shen G, Ray JC, Cicala C, Arthos J, Dustin ML, Hioe CE.

J Virol. 2016 Nov 14;90(23):10513-10526. Print 2016 Dec 1.


New Insights into How Trafficking Regulates T Cell Receptor Signaling.

Lou J, Rossy J, Deng Q, Pageon SV, Gaus K.

Front Cell Dev Biol. 2016 Jul 26;4:77. doi: 10.3389/fcell.2016.00077. eCollection 2016. Review.


A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities.

Martínez-Bonet M, Palladino C, Briz V, Rudolph JM, Fackler OT, Relloso M, Muñoz-Fernandez MA, Madrid R.

PLoS One. 2015 Dec 23;10(12):e0145239. doi: 10.1371/journal.pone.0145239. eCollection 2015.


Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells.

Fontinha D, Lopes FB, Marques S, Alenquer M, Simas JP.

PLoS One. 2015 Nov 6;10(11):e0142540. doi: 10.1371/journal.pone.0142540. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145942. Alenquer, Marta [added].


Virological Mechanisms in the Coinfection between HIV and HCV.

Liberto MC, Zicca E, Pavia G, Quirino A, Marascio N, Torti C, Focà A.

Mediators Inflamm. 2015;2015:320532. doi: 10.1155/2015/320532. Epub 2015 Oct 1. Review.


Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.

Imle A, Abraham L, Tsopoulidis N, Hoflack B, Saksela K, Fackler OT.

MBio. 2015 Sep 8;6(5):e01309-15. doi: 10.1128/mBio.01309-15.


Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer.

Xu B, Yuan L, Gao Q, Yuan P, Zhao P, Yuan H, Fan H, Li T, Qin P, Han L, Fang W, Suo Z.

Oncotarget. 2015 Aug 21;6(24):20592-603.


Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.

El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, Chomont N, Sékaly RP.

J Gen Virol. 2015 Jun;96(Pt 6):1463-77. doi: 10.1099/vir.0.000065. Epub 2015 Jan 27.


Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle?

Sehgal M, Khan ZK, Talal AH, Jain P.

Virology (Auckl). 2013 Feb 11;4:1-25. doi: 10.4137/VRT.S11046. eCollection 2013. Review.


HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.

Haller C, Müller B, Fritz JV, Lamas-Murua M, Stolp B, Pujol FM, Keppler OT, Fackler OT.

J Virol. 2014 Dec;88(24):14241-57. doi: 10.1128/JVI.02333-14. Epub 2014 Oct 1.


HIV-1 Nef is transferred from expressing T cells to hepatocytic cells through conduits and enhances HCV replication.

Park IW, Fan Y, Luo X, Ryou MG, Liu J, Green L, He JJ.

PLoS One. 2014 Jun 9;9(6):e99545. doi: 10.1371/journal.pone.0099545. eCollection 2014.


Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef.

Geist MM, Pan X, Bender S, Bartenschlager R, Nickel W, Fackler OT.

J Biol Chem. 2014 May 16;289(20):14030-44. doi: 10.1074/jbc.M114.563528. Epub 2014 Apr 4.

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