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ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

Leung JW, Makharashvili N, Agarwal P, Chiu LY, Pourpre R, Cammarata MB, Cannon JR, Sherker A, Durocher D, Brodbelt JS, Paull TT, Miller KM.

Genes Dev. 2017 Feb 1;31(3):260-274. doi: 10.1101/gad.292516.116. Epub 2017 Feb 27.


The role of deubiquitinases in breast cancer.

Xiao Z, Zhang P, Ma L.

Cancer Metastasis Rev. 2016 Dec;35(4):589-600. doi: 10.1007/s10555-016-9640-2.


The Lys63-deubiquitylating Enzyme BRCC36 Limits DNA Break Processing and Repair.

Ng HM, Wei L, Lan L, Huen MS.

J Biol Chem. 2016 Jul 29;291(31):16197-207. doi: 10.1074/jbc.M116.731927. Epub 2016 Jun 10.


BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro.

Tu Z, Xu B, Qu C, Tao Y, Chen C, Hua W, Feng G, Chang H, Liu Z, Li G, Jiang C, Yi W, Zeng M, Xia Y.

Radiat Oncol. 2015 May 30;10:123. doi: 10.1186/s13014-015-0427-3.


Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide.

Chai KM, Wang CY, Liaw HJ, Fang KM, Yang CS, Tzeng SF.

Oncotarget. 2014 Nov 15;5(21):10901-15.


Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.

Yu H, Pak H, Hammond-Martel I, Ghram M, Rodrigue A, Daou S, Barbour H, Corbeil L, Hébert J, Drobetsky E, Masson JY, Di Noia JM, Affar el B.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):285-90. doi: 10.1073/pnas.1309085110. Epub 2013 Dec 17.


Deubiquitylating enzymes and DNA damage response pathways.

Jacq X, Kemp M, Martin NM, Jackson SP.

Cell Biochem Biophys. 2013 Sep;67(1):25-43. doi: 10.1007/s12013-013-9635-3. Review.


Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.

Jamsai D, O'Connor AE, Deboer KD, Clark BJ, Smith SJ, Browne CM, Bensley JG, Merriman JA, Yuen WS, Koopman P, Jones KT, O'Bryan MK.

PLoS One. 2013;8(2):e56955. doi: 10.1371/journal.pone.0056955. Epub 2013 Feb 22.


ZNF-mediated resistance to imatinib mesylate in gastrointestinal stromal tumor.

Rink L, Ochs MF, Zhou Y, von Mehren M, Godwin AK.

PLoS One. 2013;8(1):e54477. doi: 10.1371/journal.pone.0054477. Epub 2013 Jan 25.


An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.

Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK.

PLoS One. 2012;7(10):e47086. doi: 10.1371/journal.pone.0047086. Epub 2012 Oct 9.


BRCA1 tumor suppressor network: focusing on its tail.

Wang B.

Cell Biosci. 2012 Feb 27;2(1):6. doi: 10.1186/2045-3701-2-6.


NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes.

Hu X, Kim JA, Castillo A, Huang M, Liu J, Wang B.

J Biol Chem. 2011 Apr 1;286(13):11734-45. doi: 10.1074/jbc.M110.200857. Epub 2011 Jan 31.


Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.

Oberle C, Blattner C.

Curr Genomics. 2010 May;11(3):184-98. doi: 10.2174/138920210791110979.


BRCC36A is epistatic to BRCA1 in DNA crosslink repair and homologous recombination in Arabidopsis thaliana.

Block-Schmidt AS, Dukowic-Schulze S, Wanieck K, Reidt W, Puchta H.

Nucleic Acids Res. 2011 Jan;39(1):146-54. doi: 10.1093/nar/gkq722. Epub 2010 Sep 3.


Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.

Wiltshire TD, Lovejoy CA, Wang T, Xia F, O'Connor MJ, Cortez D.

J Biol Chem. 2010 May 7;285(19):14565-71. doi: 10.1074/jbc.M110.104745. Epub 2010 Mar 15.


BRCA1 and its toolbox for the maintenance of genome integrity.

Huen MS, Sy SM, Chen J.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):138-48. doi: 10.1038/nrm2831. Epub 2009 Dec 23. Review.


Gene expression signatures and response to imatinib mesylate in gastrointestinal stromal tumor.

Rink L, Skorobogatko Y, Kossenkov AV, Belinsky MG, Pajak T, Heinrich MC, Blanke CD, von Mehren M, Ochs MF, Eisenberg B, Godwin AK.

Mol Cancer Ther. 2009 Aug;8(8):2172-82. doi: 10.1158/1535-7163.MCT-09-0193. Epub 2009 Aug 11.


Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families.

Solyom S, Patterson-Fortin J, Pylkäs K, Greenberg RA, Winqvist R.

Breast Cancer Res Treat. 2010 Feb;120(1):165-8. doi: 10.1007/s10549-009-0453-7. Epub 2009 Jul 2.


NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

Wang B, Hurov K, Hofmann K, Elledge SJ.

Genes Dev. 2009 Mar 15;23(6):729-39. doi: 10.1101/gad.1770309. Epub 2009 Mar 4.


MERIT40 facilitates BRCA1 localization and DNA damage repair.

Feng L, Huang J, Chen J.

Genes Dev. 2009 Mar 15;23(6):719-28. doi: 10.1101/gad.1770609. Epub 2009 Mar 4.

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