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Ketamine: stimulating antidepressant treatment?

Malhi GS, Byrow Y, Cassidy F, Cipriani A, Demyttenaere K, Frye MA, Gitlin M, Kennedy SH, Ketter TA, Lam RW, McShane R, Mitchell AJ, Ostacher MJ, Rizvi SJ, Thase ME, Tohen M.

BJPsych Open. 2016 May 11;2(3):e5-e9.


Scaffold Hopping Toward Agomelatine: Novel 3, 4-Dihydroisoquinoline Compounds as Potential Antidepressant Agents.

Yang Y, Ang W, Long H, Chang Y, Li Z, Zhou L, Yang T, Deng Y, Luo Y.

Sci Rep. 2016 Oct 4;6:34711. doi: 10.1038/srep34711.


Exercise protects against methamphetamine-induced aberrant neurogenesis.

Park M, Levine H, Toborek M.

Sci Rep. 2016 Sep 28;6:34111. doi: 10.1038/srep34111.


Estrogen therapy increases BDNF expression and improves post-stroke depression in ovariectomy-treated rats.

Su Q, Cheng Y, Jin K, Cheng J, Lin Y, Lin Z, Wang L, Shao B.

Exp Ther Med. 2016 Sep;12(3):1843-1848.


Mood disorders in the elderly: prevalence, functional impact, and management challenges.

Valiengo Lda C, Stella F, Forlenza OV.

Neuropsychiatr Dis Treat. 2016 Aug 24;12:2105-14. doi: 10.2147/NDT.S94643. Review.


Reconsidering Animal Models of Major Depressive Disorder in the Elderly.

Toda S, Iguchi Y, Lin Z, Nishikawa H, Nagasawa T, Watanabe H, Minabe Y.

Front Aging Neurosci. 2016 Aug 8;8:188. doi: 10.3389/fnagi.2016.00188. No abstract available.


Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway.

Hu M, Zou W, Wang CY, Chen X, Tan HY, Zeng HY, Zhang P, Gu HF, Tang XQ.

Oxid Med Cell Longev. 2016;2016:2153745. doi: 10.1155/2016/2153745.


Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment.

Kandola A, Hendrikse J, Lucassen PJ, Yücel M.

Front Hum Neurosci. 2016 Jul 29;10:373. doi: 10.3389/fnhum.2016.00373. Review.


Association between reduced white matter integrity in the corpus callosum and serotonin transporter gene DNA methylation in medication-naive patients with major depressive disorder.

Won E, Choi S, Kang J, Kim A, Han KM, Chang HS, Tae WS, Son KR, Joe SH, Lee MS, Ham BJ.

Transl Psychiatry. 2016 Aug 9;6(8):e866. doi: 10.1038/tp.2016.137.


Swimming exercise attenuates psychological dependence and voluntary methamphetamine consumption in methamphetamine withdrawn rats.

Damghani F, Bigdeli I, Miladi-Gorji H, Fadaei A.

Iran J Basic Med Sci. 2016 Jun;19(6):594-600.


Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice.

Yao W, Zhang JC, Ishima T, Dong C, Yang C, Ren Q, Ma M, Han M, Wu J, Suganuma H, Ushida Y, Yamamoto M, Hashimoto K.

Sci Rep. 2016 Jul 29;6:30659. doi: 10.1038/srep30659.


Electroconvulsive therapy and structural neuroplasticity in neocortical, limbic and paralimbic cortex.

Pirnia T, Joshi SH, Leaver AM, Vasavada M, Njau S, Woods RP, Espinoza R, Narr KL.

Transl Psychiatry. 2016 Jun 7;6(6):e832. doi: 10.1038/tp.2016.102.


Study protocol for a randomized controlled trial to explore the effects of personalized lifestyle advices and tandem skydives on pleasure in anhedonic young adults.

van Roekel E, Masselink M, Vrijen C, Heininga VE, Bak T, Nederhof E, Oldehinkel AJ.

BMC Psychiatry. 2016 Jun 4;16:182. doi: 10.1186/s12888-016-0880-z.


Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate.

Sleiman SF, Henry J, Al-Haddad R, El Hayek L, Abou Haidar E, Stringer T, Ulja D, Karuppagounder SS, Holson EB, Ratan RR, Ninan I, Chao MV.

Elife. 2016 Jun 2;5. pii: e15092. doi: 10.7554/eLife.15092.


Erythropoietin Pathway: A Potential Target for the Treatment of Depression.

Ma C, Cheng F, Wang X, Zhai C, Yue W, Lian Y, Wang Q.

Int J Mol Sci. 2016 May 6;17(5). pii: E677. doi: 10.3390/ijms17050677. Review.


Serum BDNF levels before and after the development of mood disorders: a case-control study in a population cohort.

Ihara K, Yoshida H, Jones PB, Hashizume M, Suzuki Y, Ishijima H, Kim HK, Suzuki T, Hachisu M.

Transl Psychiatry. 2016 Apr 12;6:e782. doi: 10.1038/tp.2016.47.


Amitriptyline protects against TNF-α-induced atrophy and reduction in synaptic markers via a Trk-dependent mechanism.

O'Neill E, Kwok B, Day JS, Connor TJ, Harkin A.

Pharmacol Res Perspect. 2016 Mar 8;4(2):e00195. doi: 10.1002/prp2.195.


The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons.

Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA.

eNeuro. 2016 Mar 31;3(2). pii: ENEURO.0006-16.2016. doi: 10.1523/ENEURO.0006-16.2016.



Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH.

Depress Anxiety. 2016 Aug;33(8):689-97. doi: 10.1002/da.22501. Review.

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