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Items: 11

1.

Casitas B-Lineage Lymphoma RING Domain Inhibitors Protect Mice against High-Fat Diet-Induced Obesity and Insulin Resistance.

Wu M, Sun L, Pessetto ZY, Zang Z, Xie X, Zhong L, Su Q, Zan W, Gao X, Zhao Y, Sun Y.

PLoS One. 2015 Aug 21;10(8):e0135916. doi: 10.1371/journal.pone.0135916. eCollection 2015.

2.

Protein-Protein Interactions as New Targets for Ion Channel Drug Discovery.

Stoilova-McPhie S, Ali S, Laezza F.

Austin J Pharmacol Ther. 2013 Dec 31;1(2). pii: 5.

3.

Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.

Luchini A, Espina V, Liotta LA.

Nat Commun. 2014 Jul 22;5:4413. doi: 10.1038/ncomms5413.

4.

Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.

Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW Jr, Laezza FM, Watson CS, Briggs JM, Cunningham KA.

J Neurosci. 2013 Jan 23;33(4):1615-30. doi: 10.1523/JNEUROSCI.2656-12.2013.

5.

Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex.

Shavkunov A, Panova N, Prasai A, Veselenak R, Bourne N, Stoilova-McPhie S, Laezza F.

Assay Drug Dev Technol. 2012 Apr;10(2):148-60. doi: 10.1089/adt.2011.413. Epub 2012 Feb 24.

6.

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.

Massa SM, Yang T, Xie Y, Shi J, Bilgen M, Joyce JN, Nehama D, Rajadas J, Longo FM.

J Clin Invest. 2010 May;120(5):1774-85. doi: 10.1172/JCI41356. Epub 2010 Apr 19.

7.

Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.

Ayoub MA, Damian M, Gespach C, Ferrandis E, Lavergne O, De Wever O, Banères JL, Pin JP, Prévost GP.

J Biol Chem. 2009 Oct 16;284(42):29136-45. doi: 10.1074/jbc.M109.042333. Epub 2009 Jul 31.

8.

State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics.

Johnston CA, Willard FS, Ramer JK, Blaesius R, Roques CN, Siderovski DP.

Comb Chem High Throughput Screen. 2008 Jun;11(5):370-81. Review.

9.

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction.

Simeonov A, Yasgar A, Jadhav A, Lokesh GL, Klumpp C, Michael S, Austin CP, Natarajan A, Inglese J.

Anal Biochem. 2008 Apr 1;375(1):60-70. Epub 2007 Dec 5.

10.

In silico pharmacology for drug discovery: applications to targets and beyond.

Ekins S, Mestres J, Testa B.

Br J Pharmacol. 2007 Sep;152(1):21-37. Epub 2007 Jun 4. Review.

11.

A kinetic model for calcium dynamics in RAW 264.7 cells: 2. Knockdown response and long-term response.

Maurya MR, Subramaniam S.

Biophys J. 2007 Aug 1;93(3):729-40. Epub 2007 May 4.

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