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Items: 1 to 20 of 29

1.

Colorectal cancer liver metastases organoids retain characteristics of original tumor and acquire chemotherapy resistance.

Buzzelli JN, Ouaret D, Brown G, Allen PD, Muschel RJ.

Stem Cell Res. 2018 Mar;27:109-120. doi: 10.1016/j.scr.2018.01.016. Epub 2018 Jan 28.

2.

Glycosylation Alters Dimerization Properties of a Cell-surface Signaling Protein, Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM1).

Zhuo Y, Yang JY, Moremen KW, Prestegard JH.

J Biol Chem. 2016 Sep 16;291(38):20085-95. doi: 10.1074/jbc.M116.740050. Epub 2016 Jul 28.

3.

Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis.

Wang Y, Chen Y, Yan Y, Li X, Chen G, He N, Shen S, Chen G, Zhang C, Liao W, Liao Y, Bin J.

Sci Rep. 2016 Feb 25;6:21972. doi: 10.1038/srep21972.

4.

GPI-AP release in cellular, developmental, and reproductive biology.

Fujihara Y, Ikawa M.

J Lipid Res. 2016 Apr;57(4):538-45. doi: 10.1194/jlr.R063032. Epub 2015 Nov 22. Review.

5.

Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy.

Śledzińska A, Menger L, Bergerhoff K, Peggs KS, Quezada SA.

Mol Oncol. 2015 Dec;9(10):1936-65. doi: 10.1016/j.molonc.2015.10.008. Epub 2015 Oct 26. Review.

6.

High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion.

Li C, Culver SA, Quadri S, Ledford KL, Al-Share QY, Ghadieh HE, Najjar SM, Siragy HM.

Am J Physiol Endocrinol Metab. 2015 Nov 1;309(9):E802-10. doi: 10.1152/ajpendo.00158.2015. Epub 2015 Sep 15.

7.

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.

Arabzadeh A, Dupaul-Chicoine J, Breton V, Haftchenary S, Yumeen S, Turbide C, Saleh M, McGregor K, Greenwood CM, Akavia UD, Blumberg RS, Gunning PT, Beauchemin N.

Gut. 2016 May;65(5):821-9. doi: 10.1136/gutjnl-2014-308781. Epub 2015 Feb 9.

8.

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS.

Nature. 2015 Jan 15;517(7534):386-90. doi: 10.1038/nature13848. Epub 2014 Oct 26. Erratum in: Nature. 2016 Aug 18;536(7616):359.

9.

Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models.

Bockhorn J, Prat A, Chang YF, Liu X, Huang S, Shang M, Nwachukwu C, Gomez-Vega MJ, Harrell JC, Olopade OI, Perou CM, Liu H.

Cancer Res. 2014 Dec 15;74(24):7406-17. doi: 10.1158/0008-5472.CAN-14-1188. Epub 2014 Oct 22.

10.

CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.

Alshahrani MM, Yang E, Yip J, Ghanem SS, Abdallah SL, deAngelis AM, O'Malley CJ, Moheimani F, Najjar SM, Jackson DE.

Blood. 2014 Oct 9;124(15):2431-41. doi: 10.1182/blood-2014-04-569707. Epub 2014 Aug 1.

11.

Signaling by epithelial members of the CEACAM family - mucosal docking sites for pathogenic bacteria.

Tchoupa AK, Schuhmacher T, Hauck CR.

Cell Commun Signal. 2014 Apr 15;12:27. doi: 10.1186/1478-811X-12-27. Review.

12.

An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort.

Smith DH, Christensen IJ, Jensen NF, Markussen B, Müller S, Nielsen HJ, Brünner N, Nielsen KV.

BMC Cancer. 2013 Oct 21;13:489. doi: 10.1186/1471-2407-13-489.

13.

Targeted deletion of murine CEACAM 1 activates PI3K-Akt signaling and contributes to the expression of (Pro)renin receptor via CREB family and NF-κB transcription factors.

Huang J, Ledford KJ, Pitkin WB, Russo L, Najjar SM, Siragy HM.

Hypertension. 2013 Aug;62(2):317-23. doi: 10.1161/HYPERTENSIONAHA.113.01324. Epub 2013 Jun 3.

14.

Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection.

Chang CL, Semyonov J, Cheng PJ, Huang SY, Park JI, Tsai HJ, Lin CY, Grützner F, Soong YK, Cai JJ, Hsu SY.

PLoS One. 2013 Apr 16;8(4):e61701. doi: 10.1371/journal.pone.0061701. Print 2013.

15.

Regulation of the epithelial adhesion molecule CEACAM1 is important for palate formation.

Mima J, Koshino A, Oka K, Uchida H, Hieda Y, Nohara K, Kogo M, Chai Y, Sakai T.

PLoS One. 2013 Apr 17;8(4):e61653. doi: 10.1371/journal.pone.0061653. Print 2013.

16.

The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage.

Sappino AP, Buser R, Seguin Q, Fernet M, Lesne L, Gumy-Pause F, Reith W, Favaudon V, Mandriota SJ.

Oncogenesis. 2012 Apr 16;1:e7. doi: 10.1038/oncsis.2012.7.

17.

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.

Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, Shively JE, Jobin C, Onderdonk AB, Bry L, Weiner HL, Higgins DE, Blumberg RS.

Immunity. 2012 Nov 16;37(5):930-46. doi: 10.1016/j.immuni.2012.07.016. Epub 2012 Nov 1.

18.

Genetically modified mouse models of cancer invasion and metastasis.

Rampetsreiter P, Casanova E, Eferl R.

Drug Discov Today Dis Models. 2011 Fall;8(2-3):67-74. Epub 2011 Jul 1.

19.

CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells.

Chen Z, Chen L, Baker K, Olszak T, Zeissig S, Huang YH, Kuo TT, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS.

J Exp Med. 2011 Dec 19;208(13):2633-40. doi: 10.1084/jem.20102575. Epub 2011 Dec 5.

20.

Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.

Ghosh S, Kaw M, Patel PR, Ledford KJ, Bowman TA, McInerney MF, Erickson SK, Bourey RE, Najjar SM.

Hepat Med. 2010 May;2010(2):69-78.

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