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Items: 1 to 20 of 22


Single molecule analysis reveals reversible and irreversible steps during spliceosome activation.

Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ.

Elife. 2016 May 31;5. pii: e14166. doi: 10.7554/eLife.14166.


Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II.

Carrillo Oesterreich F, Herzel L, Straube K, Hujer K, Howard J, Neugebauer KM.

Cell. 2016 Apr 7;165(2):372-81. doi: 10.1016/j.cell.2016.02.045. Epub 2016 Mar 24.


Cajal bodies are linked to genome conformation.

Wang Q, Sawyer IA, Sung MH, Sturgill D, Shevtsov SP, Pegoraro G, Hakim O, Baek S, Hager GL, Dundr M.

Nat Commun. 2016 Mar 21;7:10966. doi: 10.1038/ncomms10966.


Biochemical defects in minor spliceosome function in the developmental disorder MOPD I.

Jafarifar F, Dietrich RC, Hiznay JM, Padgett RA.

RNA. 2014 Jul;20(7):1078-89. doi: 10.1261/rna.045187.114. Epub 2014 May 27.


A splicing-dependent transcriptional checkpoint associated with prespliceosome formation.

Chathoth KT, Barrass JD, Webb S, Beggs JD.

Mol Cell. 2014 Mar 6;53(5):779-90. doi: 10.1016/j.molcel.2014.01.017. Epub 2014 Feb 20.


Functional roles of protein splicing factors.

Chen HC, Cheng SC.

Biosci Rep. 2012 Aug;32(4):345-59. doi: 10.1042/BSR20120007. Review.


Tailoring of membrane proteins by alternative splicing of pre-mRNA.

Mittendorf KF, Deatherage CL, Ohi MD, Sanders CR.

Biochemistry. 2012 Jul 17;51(28):5541-56. Epub 2012 Jun 29. Review.


New insights into the spliceosome by single molecule fluorescence microscopy.

Hoskins AA, Gelles J, Moore MJ.

Curr Opin Chem Biol. 2011 Dec;15(6):864-70. doi: 10.1016/j.cbpa.2011.10.010. Epub 2011 Nov 5. Review.


Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain.

Görnemann J, Barrandon C, Hujer K, Rutz B, Rigaut G, Kotovic KM, Faux C, Neugebauer KM, Séraphin B.

RNA. 2011 Dec;17(12):2119-29. doi: 10.1261/rna.02646811. Epub 2011 Oct 21.


Where splicing joins chromatin.

Hnilicová J, Staněk D.

Nucleus. 2011 May-Jun;2(3):182-8. doi: 10.4161/nucl.2.3.15876. Review.


Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements.

Gunderson FQ, Merkhofer EC, Johnson TL.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2004-9. doi: 10.1073/pnas.1011982108. Epub 2011 Jan 18.


The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.

Huranová M, Ivani I, Benda A, Poser I, Brody Y, Hof M, Shav-Tal Y, Neugebauer KM, Stanek D.

J Cell Biol. 2010 Oct 4;191(1):75-86. doi: 10.1083/jcb.201004030.


Protein arginine methylation facilitates cotranscriptional recruitment of pre-mRNA splicing factors.

Chen YC, Milliman EJ, Goulet I, Côté J, Jackson CA, Vollbracht JA, Yu MC.

Mol Cell Biol. 2010 Nov;30(21):5245-56. doi: 10.1128/MCB.00359-10. Epub 2010 Sep 7.


DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle.

Kosowski TR, Keys HR, Quan TK, Ruby SW.

RNA. 2009 Jul;15(7):1345-62. doi: 10.1261/rna.1065209. Epub 2009 May 18.


Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines.

Staley JP, Woolford JL Jr.

Curr Opin Cell Biol. 2009 Feb;21(1):109-18. doi: 10.1016/ Epub 2009 Jan 21. Review.


Concurrent splicing and transcription are not sufficient to enhance splicing efficiency.

Lazarev D, Manley JL.

RNA. 2007 Sep;13(9):1546-57. Epub 2007 Jul 13.


Structural characterization of the fission yeast U5.U2/U6 spliceosome complex.

Ohi MD, Ren L, Wall JS, Gould KL, Walz T.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3195-200. Epub 2007 Feb 20.


Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.

Behzadnia N, Golas MM, Hartmuth K, Sander B, Kastner B, Deckert J, Dube P, Will CL, Urlaub H, Stark H, Lührmann R.

EMBO J. 2007 Mar 21;26(6):1737-48. Epub 2007 Mar 1.


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