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Items: 20


Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.

Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G, Diaz-Heijtz R, Mechawar N, Hökfelt TG.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8472-E8481. doi: 10.1073/pnas.1617824113. Epub 2016 Dec 9.


Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray.

Wang P, Li H, Barde S, Zhang MD, Sun J, Wang T, Zhang P, Luo H, Wang Y, Yang Y, Wang C, Svenningsson P, Theodorsson E, Hökfelt TG, Xu ZQ.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4726-35. doi: 10.1073/pnas.1609198113. Epub 2016 Jul 25.


RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.

Mitsi V, Terzi D, Purushothaman I, Manouras L, Gaspari S, Neve RL, Stratinaki M, Feng J, Shen L, Zachariou V.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):E5088-97. doi: 10.1073/pnas.1504283112. Epub 2015 Aug 24.


Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.

McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ.

Pharmacol Biochem Behav. 2015 Feb;129:87-96. doi: 10.1016/j.pbb.2014.12.007. Epub 2014 Dec 24.


A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats.

Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Santín L, Parrado C, Narváez JA, Fuxe K, Díaz-Cabiale Z.

Int J Neuropsychopharmacol. 2014 Oct 31;18(3). pii: pyu064. doi: 10.1093/ijnp/pyu064.


The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats.

Ogbonmwan YE, Schroeder JP, Holmes PV, Weinshenker D.

Psychopharmacology (Berl). 2015 Apr;232(8):1395-403. doi: 10.1007/s00213-014-3778-9. Epub 2014 Oct 31.


Galanin mediates features of neural and behavioral stress resilience afforded by exercise.

Sciolino NR, Smith JM, Stranahan AM, Freeman KG, Edwards GL, Weinshenker D, Holmes PV.

Neuropharmacology. 2015 Feb;89:255-64. doi: 10.1016/j.neuropharm.2014.09.029. Epub 2014 Oct 6.


Current approaches for the discovery of drugs that deter substance and drug abuse.

Yasgar A, Simeonov A.

Expert Opin Drug Discov. 2014 Nov;9(11):1319-31. doi: 10.1517/17460441.2014.956721. Epub 2014 Sep 24. Review.


Development of a high-throughput screening-compatible cell-based functional assay to identify small molecule probes of the galanin 3 receptor (GalR3).

Robinson J, Smith A, Sturchler E, Tabrizifard S, Kamenecka T, McDonald P.

Assay Drug Dev Technol. 2013 Oct;11(8):468-77. doi: 10.1089/adt.2013.526. Epub 2013 Oct 12.


Exercise offers anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms.

Sciolino NR, Holmes PV.

Neurosci Biobehav Rev. 2012 Oct;36(9):1965-84. doi: 10.1016/j.neubiorev.2012.06.005. Epub 2012 Jul 5. Review.


Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2.

Sagi VN, Liu T, Lu X, Bartfai T, Roberts E.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7210-5. doi: 10.1016/j.bmcl.2011.09.033. Epub 2011 Sep 25.


Differential activity by polymorphic variants of a remote enhancer that supports galanin expression in the hypothalamus and amygdala: implications for obesity, depression and alcoholism.

Davidson S, Lear M, Shanley L, Hing B, Baizan-Edge A, Herwig A, Quinn JP, Breen G, McGuffin P, Starkey A, Barrett P, MacKenzie A.

Neuropsychopharmacology. 2011 Oct;36(11):2211-21. doi: 10.1038/npp.2011.93. Epub 2011 Jun 29.


Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective.

McDevitt RA, Neumaier JF.

J Chem Neuroanat. 2011 Jul;41(4):234-46. doi: 10.1016/j.jchemneu.2011.05.001. Epub 2011 May 8. Review.


Mass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processing.

Gupta N, Bark SJ, Lu WD, Taupenot L, O'Connor DT, Pevzner P, Hook V.

J Proteome Res. 2010 Oct 1;9(10):5065-75. doi: 10.1021/pr100358b.


GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.

Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107. Epub 2010 Jul 26.


Effects of galanin on monoaminergic systems and HPA axis: Potential mechanisms underlying the effects of galanin on addiction- and stress-related behaviors.

Picciotto MR, Brabant C, Einstein EB, Kamens HM, Neugebauer NM.

Brain Res. 2010 Feb 16;1314:206-18. doi: 10.1016/j.brainres.2009.08.033. Epub 2009 Aug 20. Review.


Bidirectional regulation of stress responses by galanin in mice: involvement of galanin receptor subtype 1.

Mitsukawa K, Lu X, Bartfai T.

Neuroscience. 2009 Jun 2;160(4):837-46. doi: 10.1016/j.neuroscience.2009.02.063. Epub 2009 Mar 9.


Effects of galanin on cocaine-mediated conditioned place preference and ERK signaling in mice.

Narasimhaiah R, Kamens HM, Picciotto MR.

Psychopharmacology (Berl). 2009 May;204(1):95-102. doi: 10.1007/s00213-008-1438-7. Epub 2008 Dec 20.


Genetic susceptibility to heroin addiction: a candidate gene association study.

Levran O, Londono D, O'Hara K, Nielsen DA, Peles E, Rotrosen J, Casadonte P, Linzy S, Randesi M, Ott J, Adelson M, Kreek MJ.

Genes Brain Behav. 2008 Oct;7(7):720-9. doi: 10.1111/j.1601-183X.2008.00410.x. Epub 2008 Jun 2.


Galanin impairs cognitive abilities in rodents: relevance to Alzheimer's disease.

Crawley JN.

Cell Mol Life Sci. 2008 Jun;65(12):1836-41. doi: 10.1007/s00018-008-8158-3. Review.

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