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Items: 1 to 20 of 30

1.

Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies.

Xiao X, Chang H, Li M.

Mol Psychiatry. 2017 Apr;22(4):497-511. doi: 10.1038/mp.2016.241. Epub 2017 Jan 3. Review.

2.

Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval.

Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G.

Front Genet. 2016 Jun 23;7:120. doi: 10.3389/fgene.2016.00120. eCollection 2016.

3.

Histone Modifications in a Mouse Model of Early Adversities and Panic Disorder: Role for Asic1 and Neurodevelopmental Genes.

Cittaro D, Lampis V, Luchetti A, Coccurello R, Guffanti A, Felsani A, Moles A, Stupka E, D' Amato FR, Battaglia M.

Sci Rep. 2016 Apr 28;6:25131. doi: 10.1038/srep25131.

4.

Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue.

Kundakovic M, Jiang Y, Kavanagh DH, Dincer A, Brown L, Pothula V, Zharovsky E, Park R, Jacobov R, Magro I, Kassim B, Wiseman J, Dang K, Sieberts SK, Roussos P, Fromer M, Harris B, Lipska BK, Peters MA, Sklar P, Akbarian S.

Biol Psychiatry. 2017 Jan 15;81(2):162-170. doi: 10.1016/j.biopsych.2016.03.1048. Epub 2016 Mar 9.

PMID:
27113501
5.

Understanding the genetic liability to schizophrenia through the neuroepigenome.

Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P.

Schizophr Res. 2016 Nov;177(1-3):115-124. doi: 10.1016/j.schres.2016.01.039. Epub 2016 Jan 27. Review.

PMID:
26827128
6.

Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.

Bai G, Cheung I, Shulha HP, Coelho JE, Li P, Dong X, Jakovcevski M, Wang Y, Grigorenko A, Jiang Y, Hoss A, Patel K, Zheng M, Rogaev E, Myers RH, Weng Z, Akbarian S, Chen JF.

Hum Mol Genet. 2015 Mar 1;24(5):1441-56. doi: 10.1093/hmg/ddu561. Epub 2014 Dec 5.

7.

Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia.

Mitchell AC, Jiang Y, Peter C, Akbarian S.

Schizophr Res. 2015 Sep;167(1-3):28-34. doi: 10.1016/j.schres.2014.10.020. Epub 2014 Oct 31. Review.

8.

The future of neuroepigenetics in the human brain.

Mitchell A, Roussos P, Peter C, Tsankova N, Akbarian S.

Prog Mol Biol Transl Sci. 2014;128:199-228. doi: 10.1016/B978-0-12-800977-2.00008-5. Review.

9.

Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice.

Shen EY, Ahern TH, Cheung I, Straubhaar J, Dincer A, Houston I, de Vries GJ, Akbarian S, Forger NG.

Exp Neurol. 2015 Jun;268:21-9. doi: 10.1016/j.expneurol.2014.08.006. Epub 2014 Aug 14. Review.

10.

Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients.

Wockner LF, Noble EP, Lawford BR, Young RM, Morris CP, Whitehall VL, Voisey J.

Transl Psychiatry. 2014 Jan 7;4:e339. doi: 10.1038/tp.2013.111.

11.

Postmortem brain: an underutilized substrate for studying severe mental illness.

McCullumsmith RE, Hammond JH, Shan D, Meador-Woodruff JH.

Neuropsychopharmacology. 2014 Jan;39(1):65-87. doi: 10.1038/npp.2013.239. Epub 2013 Oct 4. Review. Erratum in: Neuropsychopharmacology. 2015 Apr;40(5):1307.

12.

A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.

Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, Petryshen TL.

PLoS One. 2013 Aug 14;8(8):e71323. doi: 10.1371/journal.pone.0071323. eCollection 2013.

13.

The genome in three dimensions: a new frontier in human brain research.

Mitchell AC, Bharadwaj R, Whittle C, Krueger W, Mirnics K, Hurd Y, Rasmussen T, Akbarian S.

Biol Psychiatry. 2014 Jun 15;75(12):961-9. doi: 10.1016/j.biopsych.2013.07.015. Epub 2013 Aug 16. Review.

14.

Storage conditions and stability of global DNA methylation in placental tissue.

Vilahur N, Baccarelli AA, Bustamante M, Agramunt S, Byun HM, Fernandez MF, Sunyer J, Estivill X.

Epigenomics. 2013 Jun;5(3):341-8. doi: 10.2217/epi.13.29.

15.

Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood.

Shulha HP, Cheung I, Guo Y, Akbarian S, Weng Z.

PLoS Genet. 2013 Apr;9(4):e1003433. doi: 10.1371/journal.pgen.1003433. Epub 2013 Apr 11.

16.

Human-specific histone methylation signatures at transcription start sites in prefrontal neurons.

Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S.

PLoS Biol. 2012;10(11):e1001427. doi: 10.1371/journal.pbio.1001427. Epub 2012 Nov 20.

17.

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.

Kurita M, Holloway T, García-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umali A, Callado LF, Gallitano AL, Neve RL, Shen L, Buxbaum JD, Han MH, Nestler EJ, Meana JJ, Russo SJ, González-Maeso J.

Nat Neurosci. 2012 Sep;15(9):1245-54. doi: 10.1038/nn.3181. Epub 2012 Aug 5.

18.

Epigenetics in the human brain.

Houston I, Peter CJ, Mitchell A, Straubhaar J, Rogaev E, Akbarian S.

Neuropsychopharmacology. 2013 Jan;38(1):183-97. doi: 10.1038/npp.2012.78. Epub 2012 May 30.

19.

Epigenetics of major psychosis: progress, problems and perspectives.

Labrie V, Pai S, Petronis A.

Trends Genet. 2012 Sep;28(9):427-35. doi: 10.1016/j.tig.2012.04.002. Epub 2012 May 21. Review.

20.

Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice.

Jiang Y, Matevossian A, Guo Y, Akbarian S.

Neuropharmacology. 2011 Jun;60(7-8):1088-97. doi: 10.1016/j.neuropharm.2010.09.020. Epub 2010 Sep 30.

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