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Items: 14


Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin.

Bruell S, Sethi A, Smith N, Scott DJ, Hossain MA, Wu QP, Guo ZY, Petrie EJ, Gooley PR, Bathgate RAD.

Sci Rep. 2017 Jun 12;7(1):3294. doi: 10.1038/s41598-017-03638-4.


Assessment and significance of protein-protein interactions during development of protein biopharmaceuticals.

Yadav S, Liu J, Scherer TM, Gokarn Y, Demeule B, Kanai S, Andya JD, Shire SJ.

Biophys Rev. 2013 Jun;5(2):121-136. doi: 10.1007/s12551-013-0109-z. Epub 2013 Mar 14. Review.


Relaxin family peptides: structure-activity relationship studies.

Patil NA, Rosengren KJ, Separovic F, Wade JD, Bathgate RAD, Hossain MA.

Br J Pharmacol. 2017 May;174(10):950-961. doi: 10.1111/bph.13684. Epub 2017 Jan 19. Review.


In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR Family.

Petrie EJ, Lagaida S, Sethi A, Bathgate RA, Gooley PR.

Front Endocrinol (Lausanne). 2015 Sep 7;6:137. doi: 10.3389/fendo.2015.00137. eCollection 2015. Review.


Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability.

Nair VB, Bathgate RA, Separovic F, Samuel CS, Hossain MA, Wade JD.

Biomed Res Int. 2015;2015:731852. doi: 10.1155/2015/731852. Epub 2015 Jan 22.


Insulin: a small protein with a long journey.

Hua Q.

Protein Cell. 2010 Jun;1(6):537-51. doi: 10.1007/s13238-010-0069-z. Review.


Toward the estimation of the absolute quality of individual protein structure models.

Benkert P, Biasini M, Schwede T.

Bioinformatics. 2011 Feb 1;27(3):343-50. doi: 10.1093/bioinformatics/btq662. Epub 2010 Dec 5.


Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor.

Büllesbach EE, Hass MA, Jensen MR, Hansen DF, Kristensen SM, Schwabe C, Led JJ.

Biochemistry. 2008 Dec 16;47(50):13308-17.


Regulation of receptor signaling by relaxin A chain motifs: derivation of pan-specific and LGR7-specific human relaxin analogs.

Park JI, Semyonov J, Yi W, Chang CL, Hsu SY.

J Biol Chem. 2008 Nov 14;283(46):32099-109. doi: 10.1074/jbc.M806817200. Epub 2008 Sep 3.


Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist.

Haugaard-Jönsson LM, Hossain MA, Daly NL, Bathgate RA, Wade JD, Craik DJ, Rosengren KJ.

J Biol Chem. 2008 Aug 29;283(35):23811-8. doi: 10.1074/jbc.M800489200. Epub 2008 Jun 24.


Intra-A chain disulphide bond forms first during insulin precursor folding.

Yuan Y, Wang ZH, Tang JG.

Biochem J. 1999 Oct 1;343 Pt 1:139-44.


Principles of protein-protein interactions.

Jones S, Thornton JM.

Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):13-20. Review.


Catching a common fold.

Blundell TL, Johnson MS.

Protein Sci. 1993 Jun;2(6):877-83. Review. No abstract available.

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