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Items: 20


Circadian Regulation of Benzo[a]Pyrene Metabolism and DNA Adduct Formation in Breast Cells and the Mouse Mammary Gland.

Schmitt EE, Barhoumi R, Metz RP, Porter WW.

Mol Pharmacol. 2017 Mar;91(3):178-188. doi: 10.1124/mol.116.106740. Epub 2016 Dec 22.


An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells.

Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Landesman E, Laklouk I, Sarita-Reyes C, Gusenleitner D, Li A, Monti S, Manteiga S, Lee K, Sherr DH.

Mol Pharmacol. 2016 Nov;90(5):674-688. Epub 2016 Aug 29.


Deficiency in Aryl Hydrocarbon Receptor (AHR) Expression throughout Aging Alters Gene Expression Profiles in Murine Long-Term Hematopoietic Stem Cells.

Bennett JA, Singh KP, Unnisa Z, Welle SL, Gasiewicz TA.

PLoS One. 2015 Jul 24;10(7):e0133791. doi: 10.1371/journal.pone.0133791. eCollection 2015.


Interplay between Dioxin-mediated signaling and circadian clock: a possible determinant in metabolic homeostasis.

Wang C, Zhang ZM, Xu CX, Tischkau SA.

Int J Mol Sci. 2014 Jul 1;15(7):11700-12. doi: 10.3390/ijms150711700. Review.


The Ah receptor in stem cell cycling, regulation, and quiescence.

Gasiewicz TA, Singh KP, Bennett JA.

Ann N Y Acad Sci. 2014 Mar;1310:44-50. doi: 10.1111/nyas.12361. Epub 2014 Feb 3. Review.


Persistent polar depletion of stratospheric ozone and emergent mechanisms of ultraviolet radiation-mediated health dysregulation.

Dugo MA, Han F, Tchounwou PB.

Rev Environ Health. 2012;27(2-3):103-16. doi: 10.1515/reveh-2012-0026. Review.


Circadian rhythm disruption in cancer biology.

Savvidis C, Koutsilieris M.

Mol Med. 2012 Dec 6;18:1249-60. doi: 10.2119/molmed.2012.00077. Review.


The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis.

Lindsey S, Papoutsakis ET.

Stem Cell Rev. 2012 Dec;8(4):1223-35. doi: 10.1007/s12015-012-9384-5. Review.


The mammalian circadian system is resistant to dioxin.

Pendergast JS, Yamazaki S.

J Biol Rhythms. 2012 Apr;27(2):156-63. doi: 10.1177/0748730411434405.


Reproductive and developmental toxicity of dioxin in fish.

King-Heiden TC, Mehta V, Xiong KM, Lanham KA, Antkiewicz DS, Ganser A, Heideman W, Peterson RE.

Mol Cell Endocrinol. 2012 May 6;354(1-2):121-38. doi: 10.1016/j.mce.2011.09.027. Epub 2011 Sep 21. Review.


Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-α pathway activity in mice.

Wang C, Xu CX, Krager SL, Bottum KM, Liao DF, Tischkau SA.

Environ Health Perspect. 2011 Dec;119(12):1739-44. doi: 10.1289/ehp.1103593. Epub 2011 Aug 17.


Circadian clock disruption in the mouse ovary in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Tischkau SA, Jaeger CD, Krager SL.

Toxicol Lett. 2011 Mar 5;201(2):116-22. doi: 10.1016/j.toxlet.2010.12.013. Epub 2010 Dec 21.


Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions.

Singh KP, Garrett RW, Casado FL, Gasiewicz TA.

Stem Cells Dev. 2011 May;20(5):769-84. doi: 10.1089/scd.2010.0333. Epub 2010 Nov 9.


The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blood diseases.

Casado FL, Singh KP, Gasiewicz TA.

Blood Cells Mol Dis. 2010 Apr 15;44(4):199-206. doi: 10.1016/j.bcmd.2010.01.005. Epub 2010 Feb 19. Review.


Identification of stage-specific gene modulation during early thymocyte development by whole-genome profiling analysis after aryl hydrocarbon receptor activation.

Laiosa MD, Mills JH, Lai ZW, Singh KP, Middleton FA, Gasiewicz TA, Silverstone AE.

Mol Pharmacol. 2010 May;77(5):773-83. doi: 10.1124/mol.109.062497. Epub 2010 Feb 16.


Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene.

Xu CX, Krager SL, Liao DF, Tischkau SA.

Toxicol Sci. 2010 May;115(1):98-108. doi: 10.1093/toxsci/kfq022. Epub 2010 Jan 27.


The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications for benzene-induced hematopoietic toxicity.

Gasiewicz TA, Singh KP, Casado FL.

Chem Biol Interact. 2010 Mar 19;184(1-2):246-51. doi: 10.1016/j.cbi.2009.10.019. Epub 2009 Nov 5. Review.


The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other stem/progenitor cell populations.

Singh KP, Casado FL, Opanashuk LA, Gasiewicz TA.

Biochem Pharmacol. 2009 Feb 15;77(4):577-87. doi: 10.1016/j.bcp.2008.10.001. Epub 2008 Oct 15. Review.


Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered numbers and function of hematopoietic stem cells.

Singh KP, Wyman A, Casado FL, Garrett RW, Gasiewicz TA.

Carcinogenesis. 2009 Jan;30(1):11-9. doi: 10.1093/carcin/bgn224. Epub 2008 Sep 26.


Behavioral rhythmicity of mice lacking AhR and attenuation of light-induced phase shift by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Mukai M, Lin TM, Peterson RE, Cooke PS, Tischkau SA.

J Biol Rhythms. 2008 Jun;23(3):200-10. doi: 10.1177/0748730408316022.

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