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Items: 1 to 20 of 285


Dying to protect: cell death and the control of T-cell homeostasis.

Li KP, Shanmuganad S, Carroll K, Katz JD, Jordan MB, Hildeman DA.

Immunol Rev. 2017 May;277(1):21-43. doi: 10.1111/imr.12538. Review.


AKT/PKB Signaling: Navigating the Network.

Manning BD, Toker A.

Cell. 2017 Apr 20;169(3):381-405. doi: 10.1016/j.cell.2017.04.001. Review.


Reactive oxygen species are required for zoledronic acid-induced apoptosis in osteoclast precursors and mature osteoclast-like cells.

Tai TW, Chen CY, Su FC, Tu YK, Tsai TT, Lin CF, Jou IM.

Sci Rep. 2017 Mar 10;7:44245. doi: 10.1038/srep44245.


The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.

Nishida Y, Maeda A, Kim MJ, Cao L, Kubota Y, Ishizawa J, AlRawi A, Kato Y, Iwama A, Fujisawa M, Matsue K, Weetall M, Dumble M, Andreeff M, Davis TW, Branstrom A, Kimura S, Kojima K.

Blood Cancer J. 2017 Feb 17;7(2):e527. doi: 10.1038/bcj.2017.8.


Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells.

Modi P, Balakrishnan K, Yang Q, Wierda WG, Keating MJ, Gandhi V.

Oncotarget. 2017 Mar 7;8(10):16259-16274. doi: 10.18632/oncotarget.15180.


Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival.

Viant C, Guia S, Hennessy RJ, Rautela J, Pham K, Bernat C, Goh W, Jiao Y, Delconte R, Roger M, Simon V, Souza-Fonseca-Guimaraes F, Grabow S, Belz GT, Kile BT, Strasser A, Gray D, Hodgkin PD, Beutler B, Vivier E, Ugolini S, Huntington ND.

J Exp Med. 2017 Feb;214(2):491-510. doi: 10.1084/jem.20160869. Epub 2017 Jan 5.


GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration.

Wakatsuki S, Tokunaga S, Shibata M, Araki T.

J Cell Biol. 2017 Feb;216(2):477-493. doi: 10.1083/jcb.201606020. Epub 2017 Jan 4.


Nedaplatin enhanced apoptotic effects of ABT-737 in human cancer cells via Mcl-1 inhibition.

Zhang C, Li YL, Weng X, Li LY, Zhou MX, Zhang DY, Lin NM.

Oncol Lett. 2016 Nov;12(5):4195-4202. Epub 2016 Sep 20.


AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival.

Romorini L, Garate X, Neiman G, Luzzani C, Furmento VA, Guberman AS, Sevlever GE, Scassa ME, Miriuka SG.

Sci Rep. 2016 Oct 20;6:35660. doi: 10.1038/srep35660.


Antigen-affinity controls pre-germinal centser B cell selection by promoting Mcl-1 induction through BAFF receptor signaling.

Wensveen FM, Slinger E, van Attekum MH, Brink R, Eldering E.

Sci Rep. 2016 Oct 20;6:35673. doi: 10.1038/srep35673.


Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified.

Chu R, Alford SE, Hart K, Kothari A, Mackintosh SG, Kovak MR, Chambers TC.

Oncotarget. 2016 Nov 29;7(48):78958-78970. doi: 10.18632/oncotarget.12586.


Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis.

Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG.

Circ J. 2016 Oct 25;80(11):2259-2268. Epub 2016 Oct 8. Review.


Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks.

Enciso J, Mayani H, Mendoza L, Pelayo R.

Front Physiol. 2016 Aug 19;7:349. doi: 10.3389/fphys.2016.00349. eCollection 2016.


Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis.

Ohmer M, Weber A, Sutter G, Ehrhardt K, Zimmermann A, Häcker G.

Cell Death Dis. 2016 Aug 18;7(8):e2340. doi: 10.1038/cddis.2016.242.


Hyperbaric Oxygen Reduces Production of Reactive Oxygen Species in Neutrophils from Polytraumatized Patients Yielding in the Inhibition of p38 MAP Kinase and Downstream Pathways.

Grimberg-Peters D, Büren C, Windolf J, Wahlers T, Paunel-Görgülü A.

PLoS One. 2016 Aug 16;11(8):e0161343. doi: 10.1371/journal.pone.0161343. eCollection 2016.


Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells.

Park SH, Lee DH, Kim JL, Kim BR, Na YJ, Jo MJ, Jeong YA, Lee SY, Lee SI, Lee YY, Oh SC.

Oncotarget. 2016 Sep 13;7(37):59503-59518. doi: 10.18632/oncotarget.11147.


Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells.

Li B, Li X, Ni Z, Zhang Y, Zeng Y, Yan X, Huang Y, He J, Lyu X, Wu Y, Wang Y, Zheng Y, He F.

Oncotarget. 2016 Sep 13;7(37):59458-59470. doi: 10.18632/oncotarget.10694.


Glycogen Synthase Kinase 3β Inhibition Improves Myocardial Angiogenesis and Perfusion in a Swine Model of Metabolic Syndrome.

Potz BA, Sabe AA, Elmadhun NY, Clements RT, Robich MP, Sodha NR, Sellke FW.

J Am Heart Assoc. 2016 Jul 12;5(7). pii: e003694. doi: 10.1161/JAHA.116.003694.


FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.

Tong J, Tan S, Zou F, Yu J, Zhang L.

Oncogene. 2017 Feb 9;36(6):787-796. doi: 10.1038/onc.2016.247. Epub 2016 Jul 11.

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