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Apogossypolone (ApoG2) induces ROS-dependent apoptosis and reduces invasiveness of PC12 cells in vitro and in vivo.

Lin D, Li X, Xu L, Lian J, Xu Y, Meng L, Xie X, Wang X, He H, Xu D, Wang C, Zhu Y.

Am J Transl Res. 2017 Sep 15;9(9):3990-4002. eCollection 2017.


Identification of novel small molecule Beclin 1 mimetics activating autophagy.

Yu J, Lan L, Lewin SJ, Rogers SA, Roy A, Wu X, Gao P, Karanicolas J, Aubé J, Sun B, Xu L.

Oncotarget. 2017 May 18;8(31):51355-51369. doi: 10.18632/oncotarget.17977. eCollection 2017 Aug 1.


Autophagy in Cancer Therapy.

Fulda S.

Front Oncol. 2017 Jun 15;7:128. doi: 10.3389/fonc.2017.00128. eCollection 2017. Review.


RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas.

Blum AE, Venkitachalam S, Guo Y, Kieber-Emmons AM, Ravi L, Chandar AK, Iyer PG, Canto MI, Wang JS, Shaheen NJ, Barnholtz-Sloan JS, Markowitz SD, Willis JE, Shyr Y, Chak A, Varadan V, Guda K.

Cancer Res. 2016 Oct 1;76(19):5628-5633. Epub 2016 Aug 8.


Oncosuppressive functions of decorin.

Neill T, Schaefer L, Iozzo RV.

Mol Cell Oncol. 2015 Feb 25;2(3):e975645. doi: 10.4161/23723556.2014.975645. eCollection 2015 Jul-Sep. Review.


Functional role of autophagy in gastric cancer.

Qian HR, Yang Y.

Oncotarget. 2016 Apr 5;7(14):17641-51. doi: 10.18632/oncotarget.7508. Review.


Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization.

Maier P, Hartmann L, Wenz F, Herskind C.

Int J Mol Sci. 2016 Jan 14;17(1). pii: E102. doi: 10.3390/ijms17010102. Review.


A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells.

Dutta D, Chakraborty B, Sarkar A, Chowdhury C, Das P.

BMC Cancer. 2016 Jan 16;16:23. doi: 10.1186/s12885-016-2055-1.


MicroRNAs: an emerging player in autophagy.

Yang Y, Liang C.

ScienceOpen Res. 2015;2015. doi: 10.14293/S2199-1006.1.SOR-LIFE.A181CU.v1. Epub 2014 Dec 22.


GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3.

Zhang D, Zhang W, Li D, Fu M, Chen R, Zhan Q.

Autophagy. 2015;11(12):2247-58. doi: 10.1080/15548627.2015.1112484.


IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway.

Qin B, Zhou Z, He J, Yan C, Ding S.

Sci Rep. 2015 Nov 9;5:15701. doi: 10.1038/srep15701.


Decorin as a multivalent therapeutic agent against cancer.

Neill T, Schaefer L, Iozzo RV.

Adv Drug Deliv Rev. 2016 Feb 1;97:174-85. doi: 10.1016/j.addr.2015.10.016. Epub 2015 Oct 30. Review.


Salmonella overcomes tumor immune tolerance by inhibition of tumor indoleamine 2, 3-dioxygenase 1 expression.

Kuan YD, Lee CH.

Oncotarget. 2016 Jan 5;7(1):374-85. doi: 10.18632/oncotarget.6258.


The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control.

Hindupur SK, González A, Hall MN.

Cold Spring Harb Perspect Biol. 2015 Aug 3;7(8):a019141. doi: 10.1101/cshperspect.a019141. Review.


Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).

Mani J, Vallo S, Rakel S, Antonietti P, Gessler F, Blaheta R, Bartsch G, Michaelis M, Cinatl J, Haferkamp A, Kögel D.

BMC Cancer. 2015 Apr 7;15:224. doi: 10.1186/s12885-015-1239-4.


Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells.

Grimaldi A, Santini D, Zappavigna S, Lombardi A, Misso G, Boccellino M, Desiderio V, Vitiello PP, Di Lorenzo G, Zoccoli A, Pantano F, Caraglia M.

Cancer Biol Ther. 2015;16(4):567-79. doi: 10.1080/15384047.2015.1018494. Epub 2015 Apr 11.


PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells.

Rah B, ur Rasool R, Nayak D, Yousuf SK, Mukherjee D, Kumar LD, Goswami A.

Autophagy. 2015;11(2):314-31. doi: 10.1080/15548627.2015.1017182.


The expression of the autophagy gene beclin-1 mRNA and protein in ectopic and eutopic endometrium of patients with endometriosis.

Zhang L, Liu Y, Xu Y, Wu H, Wei Z, Cao Y.

Int J Fertil Steril. 2015 Jan-Mar;8(4):429-36. Epub 2015 Feb 7.


Autophagy in malignant transformation and cancer progression.

Galluzzi L, Pietrocola F, Bravo-San Pedro JM, Amaravadi RK, Baehrecke EH, Cecconi F, Codogno P, Debnath J, Gewirtz DA, Karantza V, Kimmelman A, Kumar S, Levine B, Maiuri MC, Martin SJ, Penninger J, Piacentini M, Rubinsztein DC, Simon HU, Simonsen A, Thorburn AM, Velasco G, Ryan KM, Kroemer G.

EMBO J. 2015 Apr 1;34(7):856-80. doi: 10.15252/embj.201490784. Epub 2015 Feb 23. Review.

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