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Items: 13


WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice.

Takahashi D, Mori T, Sohara E, Tanaka M, Chiga M, Inoue Y, Nomura N, Zeniya M, Ochi H, Takeda S, Suganami T, Rai T, Uchida S.

EBioMedicine. 2017 Apr;18:118-127. doi: 10.1016/j.ebiom.2017.03.011. Epub 2017 Mar 8.


Multistep regulation of autophagy by WNK1.

Gallolu Kankanamalage S, Lee AY, Wichaidit C, Lorente-Rodriguez A, Shah AM, Stippec S, Whitehurst AW, Cobb MH.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14342-14347. Epub 2016 Nov 28.


Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.

Dbouk HA, Weil LM, Perera GK, Dellinger MT, Pearson G, Brekken RA, Cobb MH.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15999-6004. doi: 10.1073/pnas.1419057111. Epub 2014 Oct 31.


Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation.

Björner S, Fitzpatrick PA, Li Y, Allred C, Howell A, Ringberg A, Olsson H, Miller CJ, Axelson H, Landberg G.

PLoS One. 2014 Aug 14;9(8):e105099. doi: 10.1371/journal.pone.0105099. eCollection 2014.


LINGO-1 receptor promotes neuronal apoptosis by inhibiting WNK3 kinase activity.

Zhang Z, Xu X, Xiang Z, Yu Z, Feng J, He C.

J Biol Chem. 2013 Apr 26;288(17):12152-60. doi: 10.1074/jbc.M112.447771. Epub 2013 Mar 12.


A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo.

Oi K, Sohara E, Rai T, Misawa M, Chiga M, Alessi DR, Sasaki S, Uchida S.

Biol Open. 2012 Feb 15;1(2):120-7. doi: 10.1242/bio.2011048. Epub 2011 Nov 24.


With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume.

Haas BR, Cuddapah VA, Watkins S, Rohn KJ, Dy TE, Sontheimer H.

Am J Physiol Cell Physiol. 2011 Nov;301(5):C1150-60. doi: 10.1152/ajpcell.00203.2011. Epub 2011 Aug 3.


The WNKs: atypical protein kinases with pleiotropic actions.

McCormick JA, Ellison DH.

Physiol Rev. 2011 Jan;91(1):177-219. doi: 10.1152/physrev.00017.2010. Review.


WNK1 is required for mitosis and abscission.

Tu SW, Bugde A, Luby-Phelps K, Cobb MH.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1385-90. doi: 10.1073/pnas.1018567108. Epub 2011 Jan 10.


The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways.

Zachara NE, Molina H, Wong KY, Pandey A, Hart GW.

Amino Acids. 2011 Mar;40(3):793-808. doi: 10.1007/s00726-010-0695-z. Epub 2010 Jul 31.


LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension.

Zhang Z, Xu X, Zhang Y, Zhou J, Yu Z, He C.

J Biol Chem. 2009 Jun 5;284(23):15717-28. doi: 10.1074/jbc.M808751200. Epub 2009 Apr 10.


WNK kinases and renal sodium transport in health and disease: an integrated view.

McCormick JA, Yang CL, Ellison DH.

Hypertension. 2008 Mar;51(3):588-96. doi: 10.1161/HYPERTENSIONAHA.107.103788. Epub 2008 Jan 22. Review. No abstract available.


The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.

Yang CL, Zhu X, Ellison DH.

J Clin Invest. 2007 Nov;117(11):3403-11.

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