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Items: 9


The bacterial effector VopL organizes actin into filament-like structures.

Zahm JA, Padrick SB, Chen Z, Pak CW, Yunus AA, Henry L, Tomchick DR, Chen Z, Rosen MK.

Cell. 2013 Oct 10;155(2):423-34. doi: 10.1016/j.cell.2013.09.019.


Mechanism of actin filament nucleation by the bacterial effector VopL.

Yu B, Cheng HC, Brautigam CA, Tomchick DR, Rosen MK.

Nat Struct Mol Biol. 2011 Aug 28;18(9):1068-74. doi: 10.1038/nsmb.2110.


Arp2/3 complex is bound and activated by two WASP proteins.

Padrick SB, Doolittle LK, Brautigam CA, King DS, Rosen MK.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):E472-9. doi: 10.1073/pnas.1100236108. Epub 2011 Jun 15.


Hierarchical regulation of WASP/WAVE proteins.

Padrick SB, Cheng HC, Ismail AM, Panchal SC, Doolittle LK, Kim S, Skehan BM, Umetani J, Brautigam CA, Leong JM, Rosen MK.

Mol Cell. 2008 Nov 7;32(3):426-38. doi: 10.1016/j.molcel.2008.10.012.


Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway.

Leung DW, Otomo C, Chory J, Rosen MK.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12797-802. doi: 10.1073/pnas.0801232105. Epub 2008 Aug 26.


Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).

Cheng HC, Skehan BM, Campellone KG, Leong JM, Rosen MK.

Nature. 2008 Aug 21;454(7207):1009-13. doi: 10.1038/nature07160. Epub 2008 Jul 23.


Specialized podosome- or invadopodia-like structures (PILS) for focal trabecular meshwork extracellular matrix turnover.

Aga M, Bradley JM, Keller KE, Kelley MJ, Acott TS.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5353-65. doi: 10.1167/iovs.07-1666. Epub 2008 Jul 18.


CFTR surface expression and chloride currents are decreased by inhibitors of N-WASP and actin polymerization.

Ganeshan R, Nowotarski K, Di A, Nelson DJ, Kirk KL.

Biochim Biophys Acta. 2007 Feb;1773(2):192-200. Epub 2006 Oct 3.

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