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Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling.

Jaafar ZA, Oguro A, Nakamura Y, Kieft JS.

Elife. 2016 Dec 23;5. pii: e21198. doi: 10.7554/eLife.21198.


Active yeast ribosome preparation using monolithic anion exchange chromatography.

Munoz AM, Yourik P, Rajagopal V, Nanda JS, Lorsch JR, Walker SE.

RNA Biol. 2017 Feb;14(2):188-196. doi: 10.1080/15476286.2016.1270004.


eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling.

Nag N, Lin KY, Edmonds KA, Yu J, Nadkarni D, Marintcheva B, Marintchev A.

Nucleic Acids Res. 2016 Sep 6;44(15):7441-56. doi: 10.1093/nar/gkw552.


Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.

Dever TE, Kinzy TG, Pavitt GD.

Genetics. 2016 May;203(1):65-107. doi: 10.1534/genetics.115.186221. Review.


eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning.

Pisareva VP, Pisarev AV.

Nucleic Acids Res. 2014 Oct 29;42(19):12052-69. doi: 10.1093/nar/gku877.


Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A.

Li W, Klovstad M, Schüpbach T.

Development. 2014 Oct;141(20):3910-21. doi: 10.1242/dev.109306.


Molecular architecture of a eukaryotic translational initiation complex.

Fernández IS, Bai XC, Hussain T, Kelley AC, Lorsch JR, Ramakrishnan V, Scheres SH.

Science. 2013 Nov 15;342(6160):1240585. doi: 10.1126/science.1240585.


Tricks an IRES uses to enslave ribosomes.

Thompson SR.

Trends Microbiol. 2012 Nov;20(11):558-66. doi: 10.1016/j.tim.2012.08.002. Review.


The mechanism of eukaryotic translation initiation: new insights and challenges.

Hinnebusch AG, Lorsch JR.

Cold Spring Harb Perspect Biol. 2012 Oct 1;4(10). pii: a011544. doi: 10.1101/cshperspect.a011544. Review.


The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.

Luna RE, Arthanari H, Hiraishi H, Nanda J, Martin-Marcos P, Markus MA, Akabayov B, Milbradt AG, Luna LE, Seo HC, Hyberts SG, Fahmy A, Reibarkh M, Miles D, Hagner PR, O'Day EM, Yi T, Marintchev A, Hinnebusch AG, Lorsch JR, Asano K, Wagner G.

Cell Rep. 2012 Jun 28;1(6):689-702. doi: 10.1016/j.celrep.2012.04.007.


Molecular mechanism of scanning and start codon selection in eukaryotes.

Hinnebusch AG.

Microbiol Mol Biol Rev. 2011 Sep;75(3):434-67, first page of table of contents. doi: 10.1128/MMBR.00008-11. Review.


Crystallization and preliminary X-ray crystallographic analysis of eIF5BΔN and the eIF5BΔN-eIF1AΔN complex.

Zheng A, Yamamoto R, Sokabe M, Tanaka I, Yao M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1;67(Pt 6):730-3. doi: 10.1107/S1744309111015910.


The central core region of yeast ribosomal protein L11 is important for subunit joining and translational fidelity.

Rhodin MH, Rakauskaitė R, Dinman JD.

Mol Genet Genomics. 2011 Jun;285(6):505-16. doi: 10.1007/s00438-011-0623-2.


Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability.

Shin BS, Acker MG, Kim JR, Maher KN, Arefin SM, Lorsch JR, Dever TE.

RNA. 2011 Apr;17(4):687-96. doi: 10.1261/rna.2412511.


Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation.

Lorsch JR, Dever TE.

J Biol Chem. 2010 Jul 9;285(28):21203-7. doi: 10.1074/jbc.R110.119743. Review.


The mechanism of eukaryotic translation initiation and principles of its regulation.

Jackson RJ, Hellen CU, Pestova TV.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):113-27. doi: 10.1038/nrm2838. Review.


Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome.

Saini AK, Nanda JS, Lorsch JR, Hinnebusch AG.

Genes Dev. 2010 Jan 1;24(1):97-110. doi: 10.1101/gad.1871910. Erratum in: Genes Dev. 2013 May 1;27(9):1072.


Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.

Yu Y, Marintchev A, Kolupaeva VG, Unbehaun A, Veryasova T, Lai SC, Hong P, Wagner G, Hellen CU, Pestova TV.

Nucleic Acids Res. 2009 Aug;37(15):5167-82. doi: 10.1093/nar/gkp519.


IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry.

Hellen CU.

Biochim Biophys Acta. 2009 Sep-Oct;1789(9-10):558-70. doi: 10.1016/j.bbagrm.2009.06.001. Review.

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