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Items: 15

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Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives.

Costa N, Marques O, Godinho SI, Carvalho C, Leal B, Figueiredo AM, Vasconcelos C, Marinho A, Moraes-Fontes MF, Gomes da Costa A, Ponte C, Campanilho-Marques R, Cóias T, Martins AR, Viana JF, Lima M, Martins B, Fesel C.

Clin Exp Immunol. 2017 Sep;189(3):318-330. doi: 10.1111/cei.12991. Epub 2017 Jun 16.


Nuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes.

Osinalde N, Mitxelena J, Sánchez-Quiles V, Akimov V, Aloria K, Arizmendi JM, Zubiaga AM, Blagoev B, Kratchmarova I.

Mol Cell Proteomics. 2016 Jun;15(6):2076-92. doi: 10.1074/mcp.M115.057158. Epub 2016 Apr 11.


Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration.

Qin L, Jiang G, Han J, Letvin NL.

Front Immunol. 2015 Sep 29;6:510. doi: 10.3389/fimmu.2015.00510. eCollection 2015.


Multiple autoimmune-associated variants confer decreased IL-2R signaling in CD4+ CD25(hi) T cells of type 1 diabetic and multiple sclerosis patients.

Cerosaletti K, Schneider A, Schwedhelm K, Frank I, Tatum M, Wei S, Whalen E, Greenbaum C, Kita M, Buckner J, Long SA.

PLoS One. 2013 Dec 23;8(12):e83811. doi: 10.1371/journal.pone.0083811. eCollection 2013.


IL-2 coordinates IL-2-producing and regulatory T cell interplay.

Amado IF, Berges J, Luther RJ, Mailhé MP, Garcia S, Bandeira A, Weaver C, Liston A, Freitas AA.

J Exp Med. 2013 Nov 18;210(12):2707-20. doi: 10.1084/jem.20122759.


Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis.

Thomas R.

Arthritis Res Ther. 2013 Feb 4;15(1):204. doi: 10.1186/ar4130. Review.


Dendritic cells control CD4+CD25+ Treg cell suppressor function in vitro through juxtacrine delivery of IL-2.

Kulhankova K, Rouse T, Nasr ME, Field EH.

PLoS One. 2012;7(9):e43609. doi: 10.1371/journal.pone.0043609. Epub 2012 Sep 12.


Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosis.

Mannie MD, Blanchfield JL, Islam SM, Abbott DJ.

Front Immunol. 2012 Aug 20;3:255. doi: 10.3389/fimmu.2012.00255. eCollection 2012.


Quorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model.

Almeida AR, Amado IF, Reynolds J, Berges J, Lythe G, Molina-París C, Freitas AA.

Front Immunol. 2012 May 25;3:125. doi: 10.3389/fimmu.2012.00125. eCollection 2012.


Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

Busse D, de la Rosa M, Hobiger K, Thurley K, Flossdorf M, Scheffold A, Höfer T.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3058-63. doi: 10.1073/pnas.0812851107. Epub 2010 Jan 28.


Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function.

Palmer DC, Restifo NP.

Trends Immunol. 2009 Dec;30(12):592-602. doi: 10.1016/ Epub 2009 Oct 30. Review.


Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset.

Kuczma M, Podolsky R, Garge N, Daniely D, Pacholczyk R, Ignatowicz L, Kraj P.

J Immunol. 2009 Sep 15;183(6):3731-41. doi: 10.4049/jimmunol.0800601. Epub 2009 Aug 26.


Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells.

Wilson MS, Pesce JT, Ramalingam TR, Thompson RW, Cheever A, Wynn TA.

J Immunol. 2008 Nov 15;181(10):6942-54.


Differential requirement of PKC-theta in the development and function of natural regulatory T cells.

Gupta S, Manicassamy S, Vasu C, Kumar A, Shang W, Sun Z.

Mol Immunol. 2008 Dec;46(2):213-24. doi: 10.1016/j.molimm.2008.08.275. Epub 2008 Oct 8.

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