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Items: 11


(18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier.

Liow JS, Zoghbi SS, Hu S, Hall MD, Hines CS, Shetty HU, Araneta MD, Page EM, Pike VW, Kreisl WC, Herscovitch P, Gottesman MM, Theodore WH, Innis RB.

Neuroimage. 2016 Sep;138:134-140. doi: 10.1016/j.neuroimage.2016.05.045. Epub 2016 May 19.


18F-Mefway PET imaging of serotonin 1A receptors in humans: a comparison with 18F-FCWAY.

Choi JY, Lyoo CH, Kim JS, Kim KM, Kang JH, Choi SH, Kim JJ, Ryu YH.

PLoS One. 2015 Apr 1;10(4):e0121342. doi: 10.1371/journal.pone.0121342. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0127491.


First-in-human evaluation of 18F-mefway, a PET radioligand specific to serotonin-1A receptors.

Hillmer AT, Wooten DW, Bajwa AK, Higgins AT, Lao PJ, Betthauser TJ, Barnhart TE, Rowley HA, Stone CK, Johnson SC, Mukherjee J, Christian BT.

J Nucl Med. 2014 Dec;55(12):1973-9. doi: 10.2967/jnumed.114.145151. Epub 2014 Nov 13.


Effect of Animal Condition and Fluvoxamine on the Result of [(18)F]N-3-Fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) Nortropane ([(18)F]FP-CIT) PET Study in Mice.

Shin KH, Park SA, Kim SY, Lee SJ, Oh SJ, Kim JS.

Nucl Med Mol Imaging. 2012 Mar;46(1):27-33. doi: 10.1007/s13139-011-0117-5. Epub 2011 Nov 26.


Evaluation of serotonin 5-HT(1A) receptors in rodent models using [¹⁸F]mefway PET.

Saigal N, Bajwa AK, Faheem SS, Coleman RA, Pandey SK, Constantinescu CC, Fong V, Mukherjee J.

Synapse. 2013 Sep;67(9):596-608. doi: 10.1002/syn.21665. Epub 2013 Apr 18.


5-HT radioligands for human brain imaging with PET and SPECT.

Paterson LM, Kornum BR, Nutt DJ, Pike VW, Knudsen GM.

Med Res Rev. 2013 Jan;33(1):54-111. doi: 10.1002/med.20245. Epub 2011 Jun 14. Review.


Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice.

Seneca N, Zoghbi SS, Shetty HU, Tuan E, Kannan P, Taku A, Innis RB, Pike VW.

Nucl Med Biol. 2010 Apr;37(3):335-45. doi: 10.1016/j.nucmedbio.2009.12.010.


Intraperitoneal catheter placement for pharmacological imaging studies in conscious mice.

Boudreau E, Chen G, Li X, Buck K, Hitzemann R, Hickman D.

Lab Anim (NY). 2010 Jan;39(1):23-5. doi: 10.1038/laban0110-23.


PET radiotracers: crossing the blood-brain barrier and surviving metabolism.

Pike VW.

Trends Pharmacol Sci. 2009 Aug;30(8):431-40. doi: 10.1016/ Epub 2009 Jul 16. Review.


PET imaging in rats to discern temporal onset differences between 6-hydroxydopamine and tau gene vector neurodegeneration models.

Klein RL, Dayton RD, Terry TL, Vascoe C, Sunderland JJ, Tainter KH.

Brain Res. 2009 Mar 9;1259:113-22. doi: 10.1016/j.brainres.2009.01.063. Epub 2009 Feb 10.


Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 receptors with positron emission tomography, occurs by glutathionylation in rat brain.

Shetty HU, Zoghbi SS, Siméon FG, Liow JS, Brown AK, Kannan P, Innis RB, Pike VW.

J Pharmacol Exp Ther. 2008 Dec;327(3):727-35. doi: 10.1124/jpet.108.143347. Epub 2008 Sep 19. Erratum in: J Pharmacol Exp Ther. 2009 Mar;328(3):1019.

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