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Items: 1 to 20 of 99

1.

Acetylation of N-terminus and two internal amino acids is dispensable for degradation of a protein that aberrantly engages the endoplasmic reticulum translocon.

Engle SM, Crowder JJ, Watts SG, Indovina CJ, Coffey SZ, Rubenstein EM.

PeerJ. 2017 Aug 22;5:e3728. doi: 10.7717/peerj.3728. eCollection 2017.

2.

Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs.

Ho HC, MacGurn JA, Emr SD.

Mol Biol Cell. 2017 May 1;28(9):1271-1283. doi: 10.1091/mbc.E17-01-0008. Epub 2017 Mar 15.

3.

The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.

Preston GM, Brodsky JL.

Biochem J. 2017 Feb 15;474(4):445-469. doi: 10.1042/BCJ20160582. Review.

PMID:
28159894
4.

Membrane Protein Quantity Control at the Endoplasmic Reticulum.

Printsev I, Curiel D, Carraway KL 3rd.

J Membr Biol. 2016 Oct 14. [Epub ahead of print]

PMID:
27743014
5.

Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.

Kim SM, Wang Y, Nabavi N, Liu Y, Correia MA.

Drug Metab Rev. 2016 Aug;48(3):405-33. doi: 10.1080/03602532.2016.1195403. Epub 2016 Jun 20. Review.

6.

Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.

Maurer MJ, Spear ED, Yu AT, Lee EJ, Shahzad S, Michaelis S.

G3 (Bethesda). 2016 Jul 7;6(7):1853-66. doi: 10.1534/g3.116.027953.

7.

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae.

Buchanan BW, Lloyd ME, Engle SM, Rubenstein EM.

J Vis Exp. 2016 Apr 18;(110). doi: 10.3791/53975.

8.

A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation.

Zattas D, Berk JM, Kreft SG, Hochstrasser M.

J Biol Chem. 2016 Jun 3;291(23):12105-18. doi: 10.1074/jbc.M116.726877. Epub 2016 Apr 11.

9.

Protein quality control in the nucleus.

Jones RD, Gardner RG.

Curr Opin Cell Biol. 2016 Jun;40:81-89. doi: 10.1016/j.ceb.2016.03.002. Epub 2016 Mar 22. Review.

10.

Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.

Boomsma W, Nielsen SV, Lindorff-Larsen K, Hartmann-Petersen R, Ellgaard L.

PeerJ. 2016 Feb 25;4:e1725. doi: 10.7717/peerj.1725. eCollection 2016.

11.

Degradation-mediated protein quality control at the inner nuclear membrane.

Boban M, Foisner R.

Nucleus. 2016;7(1):41-9. doi: 10.1080/19491034.2016.1139273. Review.

12.

Border Safety: Quality Control at the Nuclear Envelope.

Webster BM, Lusk CP.

Trends Cell Biol. 2016 Jan;26(1):29-39. doi: 10.1016/j.tcb.2015.08.002. Epub 2015 Oct 1. Review.

13.

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.

Namba T, Chu K, Kodama R, Byun S, Yoon KW, Hiraki M, Mandinova A, Lee SW.

Oncotarget. 2015 Aug 21;6(24):19990-20001.

14.

STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites.

Hickey CM, Hochstrasser M.

Mol Biol Cell. 2015 Oct 1;26(19):3401-12. doi: 10.1091/mbc.E15-06-0436. Epub 2015 Aug 5.

15.

DNAJs: more than substrate delivery to HSPA.

Dekker SL, Kampinga HH, Bergink S.

Front Mol Biosci. 2015 Jun 30;2:35. doi: 10.3389/fmolb.2015.00035. eCollection 2015. Review.

16.

Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance.

Liu F, Koepp DM, Walters KJ.

Sci Rep. 2015 Jul 14;5:12088. doi: 10.1038/srep12088.

17.

Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum Proteins.

Crowder JJ, Geigges M, Gibson RT, Fults ES, Buchanan BW, Sachs N, Schink A, Kreft SG, Rubenstein EM.

J Biol Chem. 2015 Jul 24;290(30):18454-66. doi: 10.1074/jbc.M115.663559. Epub 2015 Jun 8.

18.

The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron.

Habeck G, Ebner FA, Shimada-Kreft H, Kreft SG.

J Cell Biol. 2015 Apr 27;209(2):261-73. doi: 10.1083/jcb.201408088. Erratum in: J Cell Biol. 2015 May 25;209(4):621. J Cell Biol. 2015 Apr 27;209(2):260.

19.

Growth-based determination and biochemical confirmation of genetic requirements for protein degradation in Saccharomyces cerevisiae.

Watts SG, Crowder JJ, Coffey SZ, Rubenstein EM.

J Vis Exp. 2015 Feb 16;(96):e52428. doi: 10.3791/52428.

20.

Atypical ubiquitylation in yeast targets lysine-less Asi2 for proteasomal degradation.

Boban M, Ljungdahl PO, Foisner R.

J Biol Chem. 2015 Jan 23;290(4):2489-95. doi: 10.1074/jbc.M114.600593. Epub 2014 Dec 9.

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