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ScaPD: a database for human scaffold proteins.

Han X, Wang J, Wang J, Liu S, Hu J, Zhu H, Qian J.

BMC Bioinformatics. 2017 Oct 3;18(Suppl 11):386. doi: 10.1186/s12859-017-1806-6.


Heterogeneous Tau-Tubulin Complexes Accelerate Microtubule Polymerization.

Li XH, Rhoades E.

Biophys J. 2017 Jun 20;112(12):2567-2574. doi: 10.1016/j.bpj.2017.05.006.


The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.

Bardwell AJ, Lagunes L, Zebarjedi R, Bardwell L.

J Biol Chem. 2017 May 26;292(21):8750-8761. doi: 10.1074/jbc.M116.767087. Epub 2017 Apr 10.


Dynamic New World: Refining Our View of Protein Structure, Function and Evolution.

Mannige RV.

Proteomes. 2014 Mar 7;2(1):128-153. doi: 10.3390/proteomes2010128. Review.


Ssp2 Binding Activates the Smk1 Mitogen-Activated Protein Kinase.

Tio CW, Omerza G, Phillips T, Lou HJ, Turk BE, Winter E.

Mol Cell Biol. 2017 May 2;37(10). pii: e00607-16. doi: 10.1128/MCB.00607-16. Print 2017 May 15.


Spatial and temporal signal processing and decision making by MAPK pathways.

Atay O, Skotheim JM.

J Cell Biol. 2017 Feb;216(2):317-330. doi: 10.1083/jcb.201609124. Epub 2017 Jan 2. Review.


Core signalling motif displaying multistability through multi-state enzymes.

Feng S, Sáez M, Wiuf C, Feliu E, Soyer OS.

J R Soc Interface. 2016 Oct;13(123). pii: 20160524.


Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination.

Groves B, Khakhar A, Nadel CM, Gardner RG, Seelig G.

Elife. 2016 Aug 15;5. pii: e15200. doi: 10.7554/eLife.15200.


Switch-like Transitions Insulate Network Motifs to Modularize Biological Networks.

Atay O, Doncic A, Skotheim JM.

Cell Syst. 2016 Aug;3(2):121-132. doi: 10.1016/j.cels.2016.06.010. Epub 2016 Jul 21.


Enzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling Networks.

Feng S, Ollivier JF, Soyer OS.

PLoS Comput Biol. 2016 May 10;12(5):e1004918. doi: 10.1371/journal.pcbi.1004918. eCollection 2016 May.


The human Na(+)/H(+) exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2.

Hendus-Altenburger R, Pedraz-Cuesta E, Olesen CW, Papaleo E, Schnell JA, Hopper JT, Robinson CV, Pedersen SF, Kragelund BB.

BMC Biol. 2016 Apr 15;14:31. doi: 10.1186/s12915-016-0252-7.


Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.

Jang ER, Jang H, Shi P, Popa G, Jeoung M, Galperin E.

J Cell Sci. 2015 Dec 1;128(23):4428-41. doi: 10.1242/jcs.177543. Epub 2015 Oct 30.


Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction.

Hu J, Neiswinger J, Zhang J, Zhu H, Qian J.

PLoS Comput Biol. 2015 Sep 22;11(9):e1004508. doi: 10.1371/journal.pcbi.1004508. eCollection 2015.


Unmasking determinants of specificity in the human kinome.

Creixell P, Palmeri A, Miller CJ, Lou HJ, Santini CC, Nielsen M, Turk BE, Linding R.

Cell. 2015 Sep 24;163(1):187-201. doi: 10.1016/j.cell.2015.08.057. Epub 2015 Sep 17.


In vivo characterization of the scaffold activity of flotillin on the membrane kinase KinC of Bacillus subtilis.

Schneider J, Mielich-Süss B, Böhme R, Lopez D.

Microbiology. 2015 Sep;161(9):1871-87. doi: 10.1099/mic.0.000137. Epub 2015 Jul 14.


Autophosphorylation of the Smk1 MAPK is spatially and temporally regulated by Ssp2 during meiotic development in yeast.

Tio CW, Omerza G, Sunder S, Winter E.

Mol Biol Cell. 2015 Oct 1;26(19):3546-55. doi: 10.1091/mbc.E15-05-0322. Epub 2015 Aug 5.


Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK.

Nagiec MJ, McCarter PC, Kelley JB, Dixit G, Elston TC, Dohlman HG.

Mol Biol Cell. 2015 Sep 15;26(18):3359-71. doi: 10.1091/mbc.E15-01-0037. Epub 2015 Jul 15.


Co-conserved MAPK features couple D-domain docking groove to distal allosteric sites via the C-terminal flanking tail.

Nguyen T, Ruan Z, Oruganty K, Kannan N.

PLoS One. 2015 Mar 23;10(3):e0119636. doi: 10.1371/journal.pone.0119636. eCollection 2015.


How MAP kinase modules function as robust, yet adaptable, circuits.

Tian T, Harding A.

Cell Cycle. 2014;13(15):2379-90. doi: 10.4161/cc.29349.


HAM-5 functions as a MAP kinase scaffold during cell fusion in Neurospora crassa.

Jonkers W, Leeder AC, Ansong C, Wang Y, Yang F, Starr TL, Camp DG 2nd, Smith RD, Glass NL.

PLoS Genet. 2014 Nov 20;10(11):e1004783. doi: 10.1371/journal.pgen.1004783. eCollection 2014 Nov.

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