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Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.

Podgorná E, Diallo I, Vangenot C, Sanchez-Mazas A, Sabbagh A, Černý V, Poloni ES.

BMC Evol Biol. 2015 Dec 1;15:263. doi: 10.1186/s12862-015-0543-6.


Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality.

Raffler J, Friedrich N, Arnold M, Kacprowski T, Rueedi R, Altmaier E, Bergmann S, Budde K, Gieger C, Homuth G, Pietzner M, Römisch-Margl W, Strauch K, Völzke H, Waldenberger M, Wallaschofski H, Nauck M, Völker U, Kastenmüller G, Suhre K.

PLoS Genet. 2015 Sep 9;11(9):e1005487. doi: 10.1371/journal.pgen.1005487.


Exploring the relationship between lifestyles, diets and genetic adaptations in humans.

Valente C, Alvarez L, Marks SJ, Lopez-Parra AM, Parson W, Oosthuizen O, Oosthuizen E, Amorim A, Capelli C, Arroyo-Pardo E, Gusmão L, Prata MJ.

BMC Genet. 2015 May 28;16:55. doi: 10.1186/s12863-015-0212-1.


PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2.

McDonagh EM, Boukouvala S, Aklillu E, Hein DW, Altman RB, Klein TE.

Pharmacogenet Genomics. 2014 Aug;24(8):409-25. doi: 10.1097/FPC.0000000000000062. Review. No abstract available.


Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery.

Sim E, Abuhammad A, Ryan A.

Br J Pharmacol. 2014 Jun;171(11):2705-25. doi: 10.1111/bph.12598. Review.


Rapid birth-and-death evolution of the xenobiotic metabolizing NAT gene family in vertebrates with evidence of adaptive selection.

Sabbagh A, Marin J, Veyssière C, Lecompte E, Boukouvala S, Poloni ES, Darlu P, Crouau-Roy B.

BMC Evol Biol. 2013 Mar 7;13:62. doi: 10.1186/1471-2148-13-62.


The date of interbreeding between Neandertals and modern humans.

Sankararaman S, Patterson N, Li H, Pääbo S, Reich D.

PLoS Genet. 2012;8(10):e1002947. doi: 10.1371/journal.pgen.1002947.


Characterization of genetic variation and natural selection at the arylamine N-acetyltransferase genes in global human populations.

Mortensen HM, Froment A, Lema G, Bodo JM, Ibrahim M, Nyambo TB, Omar SA, Tishkoff SA.

Pharmacogenomics. 2011 Nov;12(11):1545-58. doi: 10.2217/pgs.11.88.


Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.

Génin E, Schumacher M, Roujeau JC, Naldi L, Liss Y, Kazma R, Sekula P, Hovnanian A, Mockenhaupt M.

Orphanet J Rare Dis. 2011 Jul 29;6:52. doi: 10.1186/1750-1172-6-52.


Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey.

Sabbagh A, Darlu P, Crouau-Roy B, Poloni ES.

PLoS One. 2011 Apr 6;6(4):e18507. doi: 10.1371/journal.pone.0018507.


Recent and historical recombination in the admixed Norwegian Red cattle breed.

Sodeland M, Kent M, Hayes BJ, Grove H, Lien S.

BMC Genomics. 2011 Jan 14;12:33. doi: 10.1186/1471-2164-12-33.


Divergence, demography and gene loss along the human lineage.

Kim HL, Igawa T, Kawashima A, Satta Y, Takahata N.

Philos Trans R Soc Lond B Biol Sci. 2010 Aug 27;365(1552):2451-7. doi: 10.1098/rstb.2010.0004.


Evolutionary adaptations to dietary changes.

Luca F, Perry GH, Di Rienzo A.

Annu Rev Nutr. 2010 Aug 21;30:291-314. doi: 10.1146/annurev-nutr-080508-141048. Review.


Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine.

Chen X, Wang H, Zhou G, Zhang X, Dong X, Zhi L, Jin L, He F.

Environ Health Perspect. 2009 Oct;117(10):1541-8. doi: 10.1289/ehp.0800528.


Spatial patterns of variation due to natural selection in humans.

Novembre J, Di Rienzo A.

Nat Rev Genet. 2009 Nov;10(11):745-55. doi: 10.1038/nrg2632. Review.


Introducing pharmacy students to pharmacogenomic analysis.

Krynetskiy E, Lee Calligaro I.

Am J Pharm Educ. 2009 Jul 10;73(4):71.


Clinical and genetic modifiers of long-term survival in heart failure.

Cresci S, Kelly RJ, Cappola TP, Diwan A, Dries D, Kardia SL, Dorn GW 2nd.

J Am Coll Cardiol. 2009 Jul 28;54(5):432-44. doi: 10.1016/j.jacc.2009.05.009.


Multiple advantageous amino acid variants in the NAT2 gene in human populations.

Luca F, Bubba G, Basile M, Brdicka R, Michalodimitrakis E, Rickards O, Vershubsky G, Quintana-Murci L, Kozlov AI, Novelletto A.

PLoS One. 2008 Sep 5;3(9):e3136. doi: 10.1371/journal.pone.0003136.


Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.

Walraven JM, Zang Y, Trent JO, Hein DW.

Curr Drug Metab. 2008 Jul;9(6):471-86. Review.

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