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The association between phospholipase C epsilon gene (PLCE1) polymorphisms and colorectal cancer risk in a Chinese Han population: a case-control study.

Zhang Y, Gong Y, Du S, Yan M, Geng T, Feng T, Wang J, Jin T.

Int J Clin Exp Med. 2015 Oct 15;8(10):19360-6. eCollection 2015.


Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.

Cui XB, Li S, Li TT, Peng H, Jin TT, Zhang SM, Liu CX, Yang L, Shen YY, Li SG, Li N, Li Y, Hu JM, Jiang JF, Suo J, Qi Y, Liang WH, Wang LH, Dang HW, Li L, Cao WW, Wei Y, Laibo-Yin, Wu CY, Yuan XL, Zhou H, Zheng Y, Chen YZ, Li F.

Oncotarget. 2016 Jan 12;7(2):1777-95. doi: 10.18632/oncotarget.6499.


Associations of genetic variants in the PSCA, MUC1 and PLCE1 genes with stomach cancer susceptibility in a Chinese population.

Sun H, Wu X, Wu F, Li Y, Yu Z, Chen X, Chen Y, Yang W.

PLoS One. 2015 Feb 6;10(2):e0117576. doi: 10.1371/journal.pone.0117576. eCollection 2015.


Regulation of phosphatidylinositol-specific phospholipase C at the nuclear envelope in cardiac myocytes.

Smrcka AV.

J Cardiovasc Pharmacol. 2015 Mar;65(3):203-10. doi: 10.1097/FJC.0000000000000195. Review.


Association between PLCE1 rs2274223 A > G polymorphism and cancer risk: proof from a meta-analysis.

Xue W, Zhu M, Wang Y, He J, Zheng L.

Sci Rep. 2015 Jan 23;5:7986. doi: 10.1038/srep07986. Review.


Membrane-induced allosteric control of phospholipase C-β isozymes.

Charpentier TH, Waldo GL, Barrett MO, Huang W, Zhang Q, Harden TK, Sondek J.

J Biol Chem. 2014 Oct 24;289(43):29545-57. doi: 10.1074/jbc.M114.586784. Epub 2014 Sep 5.


Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.

Jakob U, Kriwacki R, Uversky VN.

Chem Rev. 2014 Jul 9;114(13):6779-805. doi: 10.1021/cr400459c. Epub 2014 Feb 6. Review. No abstract available.


Molecular targeted therapy for hepatocellular carcinoma: current and future.

Shin JW, Chung YH.

World J Gastroenterol. 2013 Oct 7;19(37):6144-55. doi: 10.3748/wjg.v19.i37.6144. Review.


Phospholipase C-β in immune cells.

Kawakami T, Xiao W.

Adv Biol Regul. 2013 Sep;53(3):249-57. doi: 10.1016/j.jbior.2013.08.001. Epub 2013 Aug 14. Review.


Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.


The inhibitory effect of Gβγ and Gβ isoform specificity on ENaC activity.

Yu L, Al-Khalili O, Duke BJ, Stockand JD, Eaton DC, Bao HF.

Am J Physiol Renal Physiol. 2013 Nov 1;305(9):F1365-73. doi: 10.1152/ajprenal.00009.2013. Epub 2013 Jul 17.


Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes.

Hajicek N, Charpentier TH, Rush JR, Harden TK, Sondek J.

Biochemistry. 2013 Jul 16;52(28):4810-9. doi: 10.1021/bi400433b. Epub 2013 Jul 9.


Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure.

Lee SJ, Leoni G, Neumann PA, Chun J, Nusrat A, Yun CC.

Mol Cell Biol. 2013 May;33(10):2016-28. doi: 10.1128/MCB.00038-13. Epub 2013 Mar 11.


Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations.

Mebarek S, Abousalham A, Magne D, Do le D, Bandorowicz-Pikula J, Pikula S, Buchet R.

Int J Mol Sci. 2013 Mar 1;14(3):5036-129. doi: 10.3390/ijms14035036.


Small molecule inhibitors of phospholipase C from a novel high-throughput screen.

Huang W, Barrett M, Hajicek N, Hicks S, Harden TK, Sondek J, Zhang Q.

J Biol Chem. 2013 Feb 22;288(8):5840-8. doi: 10.1074/jbc.M112.422501. Epub 2013 Jan 7.


γ-Synuclein interacts with phospholipase Cβ2 to modulate G protein activation.

Golebiewska U, Guo Y, Khalikaprasad N, Zurawsky C, Yerramilli VS, Scarlata S.

PLoS One. 2012;7(8):e41067. doi: 10.1371/journal.pone.0041067. Epub 2012 Aug 8.


Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.

Wang X, Barrett M, Sondek J, Harden TK, Zhang Q.

Biochemistry. 2012 Jul 3;51(26):5300-6. Epub 2012 Jun 22.


Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.

Ben-Aissa K, Patino-Lopez G, Belkina NV, Maniti O, Rosales T, Hao JJ, Kruhlak MJ, Knutson JR, Picart C, Shaw S.

J Biol Chem. 2012 May 11;287(20):16311-23. doi: 10.1074/jbc.M111.304881. Epub 2012 Mar 20.


Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.

Wang M, Zhang R, He J, Qiu L, Li J, Wang Y, Sun M, Yang Y, Wang J, Yang J, Qian J, Jin L, Ma H, Wei Q, Zhou X.

PLoS One. 2012;7(3):e31932. doi: 10.1371/journal.pone.0031932. Epub 2012 Mar 6.


The phospholipase C isozymes and their regulation.

Gresset A, Sondek J, Harden TK.

Subcell Biochem. 2012;58:61-94. doi: 10.1007/978-94-007-3012-0_3. Review.

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