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Items: 1 to 20 of 182

1.

Delineating the Common Biological Pathways Perturbed by ASD's Genetic Etiology: Lessons from Network-Based Studies.

Oron O, Elliott E.

Int J Mol Sci. 2017 Apr 14;18(4). pii: E828. doi: 10.3390/ijms18040828. Review.

PMID:
28420080
2.

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects.

Tomasoni R, Morini R, Lopez-Atalaya JP, Corradini I, Canzi A, Rasile M, Mantovani C, Pozzi D, Garlanda C, Mantovani A, Menna E, Barco A, Matteoli M.

Elife. 2017 Mar 28;6. pii: e21735. doi: 10.7554/eLife.21735.

PMID:
28347403
3.

Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?

Magdalon J, Sánchez-Sánchez SM, Griesi-Oliveira K, Sertié AL.

Int J Mol Sci. 2017 Mar 18;18(3). pii: E659. doi: 10.3390/ijms18030659. Review.

PMID:
28335463
4.

Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice.

Zannas AS, Kim JH, West AE.

Psychopharmacology (Berl). 2017 Mar;234(6):913-923. doi: 10.1007/s00213-017-4527-7. Epub 2017 Jan 23.

PMID:
28116477
5.

A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.

Lin YC, Frei JA, Kilander MB, Shen W, Blatt GJ.

Front Cell Neurosci. 2016 Nov 17;10:263. eCollection 2016. Review.

PMID:
27909399
6.

Systemic Radical Scavenger Treatment of a Mouse Model of Rett Syndrome: Merits and Limitations of the Vitamin E Derivative Trolox.

Janc OA, Hüser MA, Dietrich K, Kempkes B, Menzfeld C, Hülsmann S, Müller M.

Front Cell Neurosci. 2016 Nov 15;10:266. eCollection 2016.

PMID:
27895554
7.

Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.

Tao J, Wu H, Coronado AA, de Laittre E, Osterweil EK, Zhang Y, Bear MF.

J Neurosci. 2016 Nov 23;36(47):11946-11958.

PMID:
27881780
8.

Transcriptional dysregulation causes altered modulation of inhibition by haloperidol.

Brady LJ, Bartley AF, Li Q, McMeekin LJ, Hablitz JJ, Cowell RM, Dobrunz LE.

Neuropharmacology. 2016 Dec;111:304-313. doi: 10.1016/j.neuropharm.2016.07.034. Epub 2016 Jul 29.

PMID:
27480797
9.

Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression.

Schafer DP, Heller CT, Gunner G, Heller M, Gordon C, Hammond T, Wolf Y, Jung S, Stevens B.

Elife. 2016 Jul 26;5. pii: e15224. doi: 10.7554/eLife.15224.

PMID:
27458802
10.

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.

Nott A, Cheng J, Gao F, Lin YT, Gjoneska E, Ko T, Minhas P, Zamudio AV, Meng J, Zhang F, Jin P, Tsai LH.

Nat Neurosci. 2016 Nov;19(11):1497-1505. doi: 10.1038/nn.4347. Epub 2016 Jul 18.

PMID:
27428650
11.

The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies.

Senter RK, Ghoshal A, Walker AG, Xiang Z, Niswender CM, Conn PJ.

Curr Neuropharmacol. 2016;14(5):455-73. Review.

PMID:
27296640
12.

Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.

Kim KC, Gonzales EL, Lázaro MT, Choi CS, Bahn GH, Yoo HJ, Shin CY.

Biomol Ther (Seoul). 2016 May 1;24(3):207-43. doi: 10.4062/biomolther.2016.061. Review.

PMID:
27133257
13.

Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects.

Dong F, Jiang J, McSweeney C, Zou D, Liu L, Mao Y.

Hum Mol Genet. 2016 Jul 1;25(13):2738-2751. Epub 2016 Apr 30.

PMID:
27131348
14.

Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice.

Yang EJ, Ahn S, Lee K, Mahmood U, Kim HS.

PLoS One. 2016 Apr 12;11(4):e0153298. doi: 10.1371/journal.pone.0153298. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0157202.

PMID:
27071011
15.

mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome.

Gogliotti RG, Senter RK, Rook JM, Ghoshal A, Zamorano R, Malosh C, Stauffer SR, Bridges TM, Bartolome JM, Daniels JS, Jones CK, Lindsley CW, Conn PJ, Niswender CM.

Hum Mol Genet. 2016 May 15;25(10):1990-2004. Epub 2016 Mar 2.

PMID:
26936821
16.

Excitatory synapses are stronger in the hippocampus of Rett syndrome mice due to altered synaptic trafficking of AMPA-type glutamate receptors.

Li W, Xu X, Pozzo-Miller L.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1575-84. doi: 10.1073/pnas.1517244113. Epub 2016 Feb 29.

PMID:
26929363
17.

Acute and crucial requirement for MeCP2 function upon transition from early to late adult stages of brain maturation.

Du F, Nguyen MV, Karten A, Felice CA, Mandel G, Ballas N.

Hum Mol Genet. 2016 May 1;25(9):1690-702. doi: 10.1093/hmg/ddw038. Epub 2016 Feb 16.

PMID:
26908602
18.

Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y) ) Mice by Rolipram.

Balakrishnan S, Niebert M, Richter DW.

Front Cell Neurosci. 2016 Feb 3;10:15. doi: 10.3389/fncel.2016.00015. eCollection 2016.

PMID:
26869885
19.

Dynamic DNA methylation controls glutamate receptor trafficking and synaptic scaling.

Sweatt JD.

J Neurochem. 2016 May;137(3):312-30. doi: 10.1111/jnc.13564. Epub 2016 Mar 3. Review.

PMID:
26849493
20.

Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs.

Lyu JW, Yuan B, Cheng TL, Qiu ZL, Zhou WH.

Sci Rep. 2016 Feb 4;6:20392. doi: 10.1038/srep20392.

PMID:
26843422

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