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Items: 14

1.

Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions.

Feijóo-Bandín S, García-Vence M, García-Rúa V, Roselló-Lletí E, Portolés M, Rivera M, González-Juanatey JR, Lago F.

Channels (Austin). 2017 Jan 2;11(1):20-33. doi: 10.1080/19336950.2016.1213929. Epub 2016 Jul 20. Review.

2.

Poring over two-pore channel pore mutants.

Penny CJ, Patel S.

Messenger (Los Angel). 2015 Jun 1;4(1):46-52.

3.

Two-pore channels at the intersection of endolysosomal membrane traffic.

Marchant JS, Patel S.

Biochem Soc Trans. 2015 Jun;43(3):434-41. doi: 10.1042/BST20140303. Review.

4.

Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view.

Cai X, Wang X, Patel S, Clapham DE.

Cell Calcium. 2015 Mar;57(3):166-73. doi: 10.1016/j.ceca.2014.11.007. Epub 2014 Dec 2. Review.

5.

Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels.

Rahman T, Cai X, Brailoiu GC, Abood ME, Brailoiu E, Patel S.

Sci Signal. 2014 Nov 18;7(352):ra109. doi: 10.1126/scisignal.2005450.

6.

TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2.

Ruas M, Chuang KT, Davis LC, Al-Douri A, Tynan PW, Tunn R, Teboul L, Galione A, Parrington J.

Mol Cell Biol. 2014 Nov;34(21):3981-92. doi: 10.1128/MCB.00113-14. Epub 2014 Aug 18.

7.

Early evolution of the eukaryotic Ca2+ signaling machinery: conservation of the CatSper channel complex.

Cai X, Wang X, Clapham DE.

Mol Biol Evol. 2014 Oct;31(10):2735-40. doi: 10.1093/molbev/msu218. Epub 2014 Jul 24.

8.

The Concise Guide to PHARMACOLOGY 2013/14: ion channels.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators.

Br J Pharmacol. 2013 Dec;170(8):1607-51. doi: 10.1111/bph.12447.

9.

Obstructing toxin pathways by targeted pore blockage.

Nestorovich EM, Bezrukov SM.

Chem Rev. 2012 Dec 12;112(12):6388-430. doi: 10.1021/cr300141q. Epub 2012 Oct 11. Review. No abstract available.

10.

Two-pore channels form homo- and heterodimers.

Rietdorf K, Funnell TM, Ruas M, Heinemann J, Parrington J, Galione A.

J Biol Chem. 2011 Oct 28;286(43):37058-62. doi: 10.1074/jbc.C111.289835. Epub 2011 Sep 8.

11.

NaChBac: the long lost sodium channel ancestor.

Charalambous K, Wallace BA.

Biochemistry. 2011 Aug 16;50(32):6742-52. doi: 10.1021/bi200942y. Epub 2011 Jul 25.

12.

TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.

Pitt SJ, Funnell TM, Sitsapesan M, Venturi E, Rietdorf K, Ruas M, Ganesan A, Gosain R, Churchill GC, Zhu MX, Parrington J, Galione A, Sitsapesan R.

J Biol Chem. 2010 Nov 5;285(45):35039-46. doi: 10.1074/jbc.M110.156927. Epub 2010 Aug 18.

13.

The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores.

Zong X, Schieder M, Cuny H, Fenske S, Gruner C, Rötzer K, Griesbeck O, Harz H, Biel M, Wahl-Schott C.

Pflugers Arch. 2009 Sep;458(5):891-9. doi: 10.1007/s00424-009-0690-y. Epub 2009 Jun 26.

14.

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