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Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin-proteasome systems.

Park DI, Dournes C, Sillaber I, Ising M, Asara JM, Webhofer C, Filiou MD, Müller MB, Turck CW.

Transl Psychiatry. 2017 Apr 4;7(4):e1078. doi: 10.1038/tp.2017.39.


[EXPRESS] Cyclic GMP-dependent protein kinase-I localized in nociceptors modulates nociceptive cortical neuronal activity and pain hypersensitivity.

Gangadharan V, Wang X, Luo C.

Mol Pain. 2017 Jan;13:1744806917701743. doi: 10.1177/1744806917701743. No abstract available.


More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy.

Chen SD, Wu CL, Hwang WC, Yang DI.

Int J Mol Sci. 2017 Mar 3;18(3). pii: E545. doi: 10.3390/ijms18030545. Review.


Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.

Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, Johnson JA.

Circ Cardiovasc Genet. 2017 Jan;10(1). pii: e001404. doi: 10.1161/CIRCGENETICS.116.001404.


Brain natriuretic peptide suppresses pain induced by BmK I, a sodium channel-specific modulator, in rats.

Li ZW, Wu B, Ye P, Tan ZY, Ji YH.

J Headache Pain. 2016 Dec;17(1):90. Epub 2016 Sep 29.


Context-dependent expression of the foraging gene in field colonies of ants: the interacting roles of age, environment and task.

Ingram KK, Gordon DM, Friedman DA, Greene M, Kahler J, Peteru S.

Proc Biol Sci. 2016 Aug 31;283(1837). pii: 20160841. doi: 10.1098/rspb.2016.0841.


A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading.

Reho JJ, Kenchegowda D, Asico LD, Fisher SA.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1715-24. doi: 10.1152/ajpheart.00869.2015. Epub 2016 Apr 15.


The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes.

Ge P, Navarro ID, Kessler MM, Bernier SG, Perl NR, Sarno R, Masferrer J, Hannig G, Stamer WD.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1317-26. doi: 10.1167/iovs.15-18958.


Why is nitric oxide important for our brain?

Džoljić E, Grbatinić I, Kostić V.

Funct Neurol. 2015 Jul-Sep;30(3):159-63. Review.


Novel Perspectives in Redox Biology and Pathophysiology of Failing Myocytes: Modulation of the Intramyocardial Redox Milieu for Therapeutic Interventions-A Review Article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology.

Arcaro A, Pirozzi F, Angelini A, Chimenti C, Crotti L, Giordano C, Mancardi D, Torella D, Tocchetti CG.

Oxid Med Cell Longev. 2016;2016:6353469. doi: 10.1155/2016/6353469. Epub 2016 Jan 5. Review.


Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.

Campbell JC, Kim JJ, Li KY, Huang GY, Reger AS, Matsuda S, Sankaran B, Link TM, Yuasa K, Ladbury JE, Casteel DE, Kim C.

J Biol Chem. 2016 Mar 11;291(11):5623-33. doi: 10.1074/jbc.M115.691303. Epub 2016 Jan 14.


Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization.

Marchenkova A, Vilotti S, Fabbretti E, Nistri A.

Mol Pain. 2015 Nov 14;11:71. doi: 10.1186/s12990-015-0074-6.


Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.

Qin L, Reger AS, Guo E, Yang MP, Zwart P, Casteel DE, Kim C.

Biochemistry. 2015 Jul 28;54(29):4419-22. doi: 10.1021/acs.biochem.5b00572. Epub 2015 Jul 15.


Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats.

Xu TY, Lan XH, Guan YF, Zhang SL, Wang X, Miao CY.

Acta Pharmacol Sin. 2015 Apr;36(4):429-39. doi: 10.1038/aps.2015.5. Epub 2015 Mar 23.


Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Dasgupta A, Bowman L, D'Arsigny CL, Archer SL.

Clin Pharmacol Ther. 2015 Jan;97(1):88-102. doi: 10.1002/cpt.10. Epub 2014 Nov 28. Review.


Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells.

Vielma AH, Agurto A, Valdés J, Palacios AG, Schmachtenberg O.

PLoS One. 2014 Dec 2;9(12):e114330. doi: 10.1371/journal.pone.0114330. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119399.


Correlative intravital imaging of cGMP signals and vasodilation in mice.

Thunemann M, Schmidt K, de Wit C, Han X, Jain RK, Fukumura D, Feil R.

Front Physiol. 2014 Oct 14;5:394. doi: 10.3389/fphys.2014.00394. eCollection 2014.


Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS.

Papapetropoulos A, Hobbs AJ, Topouzis S.

Br J Pharmacol. 2015 Mar;172(6):1397-414. doi: 10.1111/bph.12980. Epub 2015 Jan 12. Review.


Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.

Fabbiano S, Menacho-Márquez M, Sevilla MA, Albarrán-Juárez J, Zheng Y, Offermanns S, Montero MJ, Bustelo XR.

Mol Cell Biol. 2014 Dec;34(24):4404-19. doi: 10.1128/MCB.01066-14. Epub 2014 Oct 6.


Novel role for protein kinase g oxidative activation in the vasodilator and antihypertensive actions of hydrogen sulfide.

Wolin MS.

Hypertension. 2014 Dec;64(6):1196-7. doi: 10.1161/HYPERTENSIONAHA.114.04376. Epub 2014 Sep 29. No abstract available.

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