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Items: 19


Thrombopoietin and its receptor in normal and neoplastic hematopoiesis.

Kaushansky K.

Thromb J. 2016 Oct 4;14(Suppl 1):40. eCollection 2016.


Allogeneic hematopoietic stem cell transplantation for nonmalignant hematologic disorders using chemotherapy-only cytoreductive regimens and T-cell-depleted grafts from human leukocyte antigen-matched or -mismatched donors.

Mussetti A, Kernan NA, Prockop SE, Scaradavou A, Lehrman R, Ruggiero JM, Curran K, Kobos R, O'Reilly R, Boulad F.

Pediatr Hematol Oncol. 2016 Sep;33(6):347-358. Epub 2016 Oct 7.


Eltrombopag for the treatment of aplastic anemia: current perspectives.

Lum SH, Grainger JD.

Drug Des Devel Ther. 2016 Sep 13;10:2833-2843. eCollection 2016. Review.


Advances in genetic studies of inherited bone marrow failure syndromes and their associated malignancies.

Yu QH, Wang SY, Wu Z.

Transl Pediatr. 2014 Oct;3(4):305-9. doi: 10.3978/j.issn.2224-4336.2014.07.06. Review.


Neonatal manifestations of inherited bone marrow failure syndromes.

Khincha PP, Savage SA.

Semin Fetal Neonatal Med. 2016 Feb;21(1):57-65. doi: 10.1016/j.siny.2015.12.003. Epub 2015 Dec 24. Review.


Severe Clinical Course in a Patient with Congenital Amegakaryocytic Thrombocytopenia Due to a Missense Mutation of the c-MPL Gene.

Ok Bozkaya İ, Yaralı N, Işık P, Ünsal Saç R, Tavil B, Tunç B.

Turk J Haematol. 2015 Jun;32(2):172-4. doi: 10.4274/tjh.2013.0191.


Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.

Kohlscheen S, Wintterle S, Schwarzer A, Kamp C, Brugman MH, Breuer DC, Büsche G, Baum C, Modlich U.

PLoS One. 2015 Jul 6;10(7):e0131866. doi: 10.1371/journal.pone.0131866. eCollection 2015.


Clinical indications for thrombopoietin and thrombopoietin-receptor agonists.

Wörmann B.

Transfus Med Hemother. 2013 Oct;40(5):319-25. doi: 10.1159/000355006. Epub 2013 Sep 11. Review.


Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling.

Hirata S, Takayama N, Jono-Ohnishi R, Endo H, Nakamura S, Dohda T, Nishi M, Hamazaki Y, Ishii E, Kaneko S, Otsu M, Nakauchi H, Kunishima S, Eto K.

J Clin Invest. 2013 Sep;123(9):3802-14. doi: 10.1172/JCI64721. Epub 2013 Aug 1.


Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases.

He X, Chen Z, Jiang Y, Qiu X, Zhao X.

J Hematol Oncol. 2013 Jan 25;6:11. doi: 10.1186/1756-8722-6-11. Review.


Outcomes after related and unrelated umbilical cord blood transplantation for hereditary bone marrow failure syndromes other than Fanconi anemia.

Bizzetto R, Bonfim C, Rocha V, Socié G, Locatelli F, Chan K, Ramirez O, Stein J, Nabhan S, Miranda E, Passweg J, de Souza CA, Gluckman E; Eurocord and SAA-WP from EBMT.

Haematologica. 2011 Jan;96(1):134-41. doi: 10.3324/haematol.2010.027839. Epub 2010 Nov 11.



Geddis AE.

Semin Hematol. 2010 Jul;47(3):212-9. doi: 10.1053/j.seminhematol.2010.03.001. Review.


Pathophysiology and management of inherited bone marrow failure syndromes.

Shimamura A, Alter BP.

Blood Rev. 2010 May;24(3):101-22. doi: 10.1016/j.blre.2010.03.002. Epub 2010 Apr 24. Review. Erratum in: Blood Rev. 2010 Jul-Sep;24(4-5):201.


Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

Wicke DC, Meyer J, Buesche G, Heckl D, Kreipe H, Li Z, Welte KH, Ballmaier M, Baum C, Modlich U.

Mol Ther. 2010 Feb;18(2):343-52. doi: 10.1038/mt.2009.233. Epub 2009 Oct 20. Erratum in: Mol Ther. 2010 Feb;18(2):448.


Thrombocytopenias: a clinical point of view.

Veneri D, Franchini M, Randon F, Nichele I, Pizzolo G, Ambrosetti A.

Blood Transfus. 2009 Apr;7(2):75-85. doi: 10.2450/2008.0012-08. Review. No abstract available.


Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii.

Geddis AE.

Hematol Oncol Clin North Am. 2009 Apr;23(2):321-31. doi: 10.1016/j.hoc.2009.01.012. Review.


Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature.

Fox NE, Chen R, Hitchcock I, Keates-Baleeiro J, Frangoul H, Geddis AE.

Exp Hematol. 2009 Apr;37(4):495-503. doi: 10.1016/j.exphem.2009.01.001. Review.


An ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominance.

Chan ER, Lavender H, Li G, Haviernik P, Bunting KD, Adams MD.

Exp Hematol. 2009 Feb;37(2):276-84. doi: 10.1016/j.exphem.2008.10.005. Epub 2008 Dec 6.

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