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Toll-like receptor expression in human non-small cell lung carcinoma: potential prognostic indicators of disease.

Bauer AK, Upham BL, Rondini EA, Tennis MA, Velmuragan K, Wiese D.

Oncotarget. 2017 Jul 22;8(54):91860-91875. doi: 10.18632/oncotarget.19463. eCollection 2017 Nov 3.


Differential innate immune cell signatures and effects regulated by toll-like receptor 4 during murine lung tumor promotion.

Alexander CM, Xiong KN, Velmurugan K, Xiong J, Osgood RS, Bauer AK.

Exp Lung Res. 2016 Apr;42(3):154-73. doi: 10.3109/01902148.2016.1164263.


Association between Toll-like receptor 7 Gln11Leu single-nucleotide polymorphism and basal cell carcinoma.

Russo I, Cona C, Saponeri A, Bassetto F, Baldo V, Alaibac M.

Biomed Rep. 2016 Apr;4(4):459-462. Epub 2016 Feb 15.


Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model.

Bauer AK, Velmurugan K, Xiong KN, Alexander CM, Xiong J, Brooks R.

Mol Carcinog. 2017 Jan;56(1):94-105. doi: 10.1002/mc.22475. Epub 2016 Feb 19.


Alcohol, TLR4-TGF-β antagonism, and liver cancer.

Tsukamoto H, Mishra L, Machida K.

Hepatol Int. 2014 Sep;8 Suppl 2:408-12. doi: 10.1007/s12072-013-9489-1. Epub 2013 Dec 27.


Different Toll-Like Receptor Expression Patterns in Progression toward Cancer.

Jouhi L, Renkonen S, Atula T, Mäkitie A, Haglund C, Hagström J.

Front Immunol. 2014 Dec 15;5:638. doi: 10.3389/fimmu.2014.00638. eCollection 2014. Review. No abstract available.


Bronchoalveolar Lavage Fluid Utilized Ex Vivo to Validate In Vivo Findings: Inhibition of Gap Junction Activity in Lung Tumor Promotion is Toll-Like Receptor 4-Dependent.

Hill T 3rd, Osgood RS, Velmurugan K, Alexander CM, Upham BL, Bauer AK.

J Mol Biomark Diagn. 2013 Dec 27;5(1). pii: 22168.


Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.

Sargent LM, Porter DW, Staska LM, Hubbs AF, Lowry DT, Battelli L, Siegrist KJ, Kashon ML, Mercer RR, Bauer AK, Chen BT, Salisbury JL, Frazer D, McKinney W, Andrew M, Tsuruoka S, Endo M, Fluharty KL, Castranova V, Reynolds SH.

Part Fibre Toxicol. 2014 Jan 9;11:3. doi: 10.1186/1743-8977-11-3.


The Yin and Yang of Toll-like receptors in cancer.

Pradere JP, Dapito DH, Schwabe RF.

Oncogene. 2014 Jul 3;33(27):3485-95. doi: 10.1038/onc.2013.302. Epub 2013 Aug 12. Review.


Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells.

Chen CL, Tsukamoto H, Liu JC, Kashiwabara C, Feldman D, Sher L, Dooley S, French SW, Mishra L, Petrovic L, Jeong JH, Machida K.

J Clin Invest. 2013 Jul;123(7):2832-49. doi: 10.1172/JCI65859. Epub 2013 Jun 10.


Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.

Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefler E, McKenna A, Carter SL, Cibulskis K, Sivachenko A, Saksena G, Voet D, Ramos AH, Auclair D, Thompson K, Sougnez C, Onofrio RC, Guiducci C, Beroukhim R, Zhou Z, Lin L, Lin J, Reddy R, Chang A, Landrenau R, Pennathur A, Ogino S, Luketich JD, Golub TR, Gabriel SB, Lander ES, Beer DG, Godfrey TE, Getz G, Bass AJ.

Nat Genet. 2013 May;45(5):478-86. doi: 10.1038/ng.2591. Epub 2013 Mar 24.


TLR agonists: our best frenemy in cancer immunotherapy.

Kaczanowska S, Joseph AM, Davila E.

J Leukoc Biol. 2013 Jun;93(6):847-63. doi: 10.1189/jlb.1012501. Epub 2013 Mar 8. Review.


Direct engagement of TLR4 in invariant NKT cells regulates immune diseases by differential IL-4 and IFN-γ production in mice.

Kim JH, Kim HS, Kim HY, Oh SJ, Chung DH.

PLoS One. 2012;7(9):e45348. doi: 10.1371/journal.pone.0045348. Epub 2012 Sep 19.


The effect of desacetyluvaricin on the expression of TLR4 and P53 protein in Hepg 2.2.15.

He HB, Wu XL, Yu B, Liu KL, Zhou GX, Qian GQ, Ju da H, Chen XY.

Hepat Mon. 2011 May;11(5):364-7.


Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice.

Bauer AK, Cho HY, Miller-Degraff L, Walker C, Helms K, Fostel J, Yamamoto M, Kleeberger SR.

PLoS One. 2011;6(10):e26590. doi: 10.1371/journal.pone.0026590. Epub 2011 Oct 21.


Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes.

Zaynagetdinov R, Stathopoulos GT, Sherrill TP, Cheng DS, McLoed AG, Ausborn JA, Polosukhin VV, Connelly L, Zhou W, Fingleton B, Peebles RS, Prince LS, Yull FE, Blackwell TS.

Oncogene. 2012 Jun 28;31(26):3164-76. doi: 10.1038/onc.2011.480. Epub 2011 Oct 17.


Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70.

Bauer AK, Rondini EA, Hummel KA, Degraff LM, Walker C, Jedlicka AE, Kleeberger SR.

Environ Health Perspect. 2011 Aug;119(8):1091-7. doi: 10.1289/ehp.1003326. Epub 2011 May 4.


Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice.

Naseemuddin M, Iqbal A, Nasti TH, Ghandhi JL, Kapadia AD, Yusuf N.

Int J Cancer. 2012 Feb 15;130(4):765-74. doi: 10.1002/ijc.26100. Epub 2011 Jun 18.


Reduced expression of Toll-like receptor 4 inhibits human breast cancer cells proliferation and inflammatory cytokines secretion.

Yang H, Zhou H, Feng P, Zhou X, Wen H, Xie X, Shen H, Zhu X.

J Exp Clin Cancer Res. 2010 Jul 10;29:92. doi: 10.1186/1756-9966-29-92.

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