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Items: 1 to 20 of 74


Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3.

Alpi AF, Chaugule V, Walden H.

Biochem J. 2016 Oct 15;473(20):3401-3419. Review.


Drosophila CG2469 Encodes a Homolog of Human CTR9 and Is Essential for Development.

Chaturvedi D, Inaba M, Scoggin S, Buszczak M.

G3 (Bethesda). 2016 Dec 7;6(12):3849-3857. doi: 10.1534/g3.116.035196.


E2 enzymes: more than just middle men.

Stewart MD, Ritterhoff T, Klevit RE, Brzovic PS.

Cell Res. 2016 Apr;26(4):423-40. doi: 10.1038/cr.2016.35. Epub 2016 Mar 22. Review.


E2 superfamily of ubiquitin-conjugating enzymes: constitutively active or activated through phosphorylation in the catalytic cleft.

Valimberti I, Tiberti M, Lambrughi M, Sarcevic B, Papaleo E.

Sci Rep. 2015 Oct 14;5:14849. doi: 10.1038/srep14849.


Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification.

Mbogning J, Pagé V, Burston J, Schwenger E, Fisher RP, Schwer B, Shuman S, Tanny JC.

Nucleic Acids Res. 2015 Nov 16;43(20):9766-75. doi: 10.1093/nar/gkv837. Epub 2015 Aug 14.


The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae.

Cucinotta CE, Young AN, Klucevsek KM, Arndt KM.

PLoS Genet. 2015 Aug 4;11(8):e1005420. doi: 10.1371/journal.pgen.1005420. eCollection 2015 Aug.


Chromatin modification by the RNA Polymerase II elongation complex.

Tanny JC.

Transcription. 2014;5(5):e988093. doi: 10.4161/21541264.2014.988093. Epub 2015 Jan 7. Review.


Post-translational modifications of histones that influence nucleosome dynamics.

Bowman GD, Poirier MG.

Chem Rev. 2015 Mar 25;115(6):2274-95. doi: 10.1021/cr500350x. Epub 2014 Nov 26. Review. No abstract available.


H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb.

Wu L, Li L, Zhou B, Qin Z, Dou Y.

Mol Cell. 2014 Jun 19;54(6):920-31. doi: 10.1016/j.molcel.2014.04.013. Epub 2014 May 15.


The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast.

Mbogning J, Nagy S, Pagé V, Schwer B, Shuman S, Fisher RP, Tanny JC.

PLoS Genet. 2013;9(12):e1004029. doi: 10.1371/journal.pgen.1004029. Epub 2013 Dec 26.


A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation.

Dronamraju R, Strahl BD.

Nucleic Acids Res. 2014 Jan;42(2):870-81. doi: 10.1093/nar/gkt1003. Epub 2013 Oct 25.


Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.

Wier AD, Mayekar MK, Héroux A, Arndt KM, VanDemark AP.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17290-5. doi: 10.1073/pnas.1314754110. Epub 2013 Oct 7.


Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development.

Venkatesh S, Workman JL.

Wiley Interdiscip Rev Dev Biol. 2013 Sep-Oct;2(5):685-700. doi: 10.1002/wdev.109. Epub 2013 Feb 1. Review.


Combining genomic and proteomic approaches for epigenetics research.

Han Y, Garcia BA.

Epigenomics. 2013 Aug;5(4):439-52. doi: 10.2217/epi.13.37. Review.


Balancing chromatin remodeling and histone modifications in transcription.

Petty E, Pillus L.

Trends Genet. 2013 Nov;29(11):621-9. doi: 10.1016/j.tig.2013.06.006. Epub 2013 Jul 16. Review.


The recruitment of the Saccharomyces cerevisiae Paf1 complex to active genes requires a domain of Rtf1 that directly interacts with the Spt4-Spt5 complex.

Mayekar MK, Gardner RG, Arndt KM.

Mol Cell Biol. 2013 Aug;33(16):3259-73. doi: 10.1128/MCB.00270-13. Epub 2013 Jun 17.


The CDK Network: Linking Cycles of Cell Division and Gene Expression.

Fisher RP.

Genes Cancer. 2012 Nov;3(11-12):731-8. doi: 10.1177/1947601912473308.


The yeast cap binding complex modulates transcription factor recruitment and establishes proper histone H3K36 trimethylation during active transcription.

Hossain MA, Chung C, Pradhan SK, Johnson TL.

Mol Cell Biol. 2013 Feb;33(4):785-99. doi: 10.1128/MCB.00947-12. Epub 2012 Dec 10.


Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.

Tomson BN, Crisucci EM, Heisler LE, Gebbia M, Nislow C, Arndt KM.

Mol Cell Biol. 2013 Jan;33(1):170-82. doi: 10.1128/MCB.01233-12. Epub 2012 Oct 29.


The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation.

Hartzog GA, Fu J.

Biochim Biophys Acta. 2013 Jan;1829(1):105-15. doi: 10.1016/j.bbagrm.2012.08.007. Epub 2012 Sep 6. Review.

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