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Efficacy of palifermin on oral mucositis and acute GVHD after hematopoietic stem cell transplantation (HSCT) in hematology malignancy patients: a meta-analysis of trials.

Mozaffari HR, Payandeh M, Ramezani M, Sadeghi M, Mahmoudiahmadabadi M, Sharifi R.

Contemp Oncol (Pozn). 2017;21(4):299-305. doi: 10.5114/wo.2017.72400. Epub 2017 Dec 30.


Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.

Dudakov JA, Mertelsmann AM, O'Connor MH, Jenq RR, Velardi E, Young LF, Smith OM, Boyd RL, van den Brink MRM, Hanash AM.

Blood. 2017 Aug 17;130(7):933-942. doi: 10.1182/blood-2017-01-762658. Epub 2017 Jun 12.


Epithelial LTβR signaling controls the population size of the progenitors of medullary thymic epithelial cells in neonatal mice.

Wu W, Shi Y, Xia H, Chai Q, Jin C, Ren B, Zhu M.

Sci Rep. 2017 Mar 14;7:44481. doi: 10.1038/srep44481.


Early recovery of T-cell function predicts improved survival after T-cell depleted allogeneic transplant.

Goldberg JD, Zheng J, Ratan R, Small TN, Lai KC, Boulad F, Castro-Malaspina H, Giralt SA, Jakubowski AA, Kernan NA, O'Reilly RJ, Papadopoulos EB, Young JW, van den Brink MR, Heller G, Perales MA.

Leuk Lymphoma. 2017 Aug;58(8):1859-1871. doi: 10.1080/10428194.2016.1265113. Epub 2017 Jan 10.


Thymus: the next (re)generation.

Chaudhry MS, Velardi E, Dudakov JA, van den Brink MR.

Immunol Rev. 2016 May;271(1):56-71. doi: 10.1111/imr.12418. Review.


Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function.

Gardner JC, Wu H, Noel JG, Ramser BJ, Pitstick L, Saito A, Nikolaidis NM, McCormack FX.

Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L868-79. doi: 10.1152/ajplung.00363.2015. Epub 2016 Feb 26.


Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.

van den Broek T, Delemarre EM, Janssen WJ, Nievelstein RA, Broen JC, Tesselaar K, Borghans JA, Nieuwenhuis EE, Prakken BJ, Mokry M, Jansen NJ, van Wijk F.

J Clin Invest. 2016 Mar 1;126(3):1126-36. doi: 10.1172/JCI84997. Epub 2016 Feb 22.


Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution.

Youm YH, Horvath TL, Mangelsdorf DJ, Kliewer SA, Dixit VD.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1026-31. doi: 10.1073/pnas.1514511113. Epub 2016 Jan 11.


Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.

Khan IS, Park CY, Mavropoulos A, Shariat N, Pollack JL, Barczak AJ, Erle DJ, McManus MT, Anderson MS, Jeker LT.

PLoS One. 2015 Aug 13;10(8):e0135440. doi: 10.1371/journal.pone.0135440. eCollection 2015.


Effects of T-Cell Depletion on Allogeneic Hematopoietic Stem Cell Transplantation Outcomes in AML Patients.

Hobbs GS, Perales MA.

J Clin Med. 2015 Mar 19;4(3):488-503. doi: 10.3390/jcm4030488. Review.


Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts.

Fan Y, Tajima A, Goh SK, Geng X, Gualtierotti G, Grupillo M, Coppola A, Bertera S, Rudert WA, Banerjee I, Bottino R, Trucco M.

Mol Ther. 2015 Jul;23(7):1262-1277. doi: 10.1038/mt.2015.77. Epub 2015 Apr 23.


The Fibroblast Growth Factor signaling pathway.

Ornitz DM, Itoh N.

Wiley Interdiscip Rev Dev Biol. 2015 May-Jun;4(3):215-66. doi: 10.1002/wdev.176. Epub 2015 Mar 13. Review.


The role of the thymus in T-cell immune reconstitution after umbilical cord blood transplantation.

Politikos I, Boussiotis VA.

Blood. 2014 Nov 20;124(22):3201-11. doi: 10.1182/blood-2014-07-589176. Epub 2014 Oct 6. Review.


c-Met signalling is required for efficient postnatal thymic regeneration and repair.

Song Y, Su M, Panchatsharam P, Rood D, Lai L.

Immunology. 2015 Feb;144(2):245-53. doi: 10.1111/imm.12365.


Regeneration of the aged thymus by a single transcription factor.

Bredenkamp N, Nowell CS, Blackburn CC.

Development. 2014 Apr;141(8):1627-37. doi: 10.1242/dev.103614.


Thymic epithelial cell development and its dysfunction in human diseases.

Sun L, Li H, Luo H, Zhao Y.

Biomed Res Int. 2014;2014:206929. doi: 10.1155/2014/206929. Epub 2014 Feb 3. Review.


T cell ageing: effects of age on development, survival & function.

Salam N, Rane S, Das R, Faulkner M, Gund R, Kandpal U, Lewis V, Mattoo H, Prabhu S, Ranganathan V, Durdik J, George A, Rath S, Bal V.

Indian J Med Res. 2013 Nov;138(5):595-608. Review.


Clinical applications of palifermin: amelioration of oral mucositis and other potential indications.

Vadhan-Raj S, Goldberg JD, Perales MA, Berger DP, van den Brink MR.

J Cell Mol Med. 2013 Nov;17(11):1371-84. doi: 10.1111/jcmm.12169. Epub 2013 Nov 19. Review.


Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture.

Awong G, Singh J, Mohtashami M, Malm M, La Motte-Mohs RN, Benveniste PM, Serra P, Herer E, van den Brink MR, Zúñiga-Pflücker JC.

Blood. 2013 Dec 19;122(26):4210-9. doi: 10.1182/blood-2012-12-472803. Epub 2013 Nov 8.


Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models.

Finch PW, Mark Cross LJ, McAuley DF, Farrell CL.

J Cell Mol Med. 2013 Sep;17(9):1065-87. doi: 10.1111/jcmm.12091. Review.

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