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Items: 14


Anxiety-like behaviors at the end of the nocturnal period in sP rats with a "history" of unpredictable, limited access to alcohol.

Colombo G, Lobina C, Maccioni P, Carai MA, Lorrai I, Zaru A, Contini A, Mugnaini C, Corelli F, Gessa GL.

Alcohol. 2015 Nov;49(7):707-12. doi: 10.1016/j.alcohol.2015.04.010. Epub 2015 Jul 21.


GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence.

Agabio R, Colombo G.

Front Neurosci. 2014 Jun 6;8:140. doi: 10.3389/fnins.2014.00140. eCollection 2014. Review.


Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice.

Hwa LS, Kalinichev M, Haddouk H, Poli S, Miczek KA.

Psychopharmacology (Berl). 2014 Jan;231(2):333-43. doi: 10.1007/s00213-013-3245-z. Epub 2013 Aug 22.


Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.

Koek W, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2013 Mar;344(3):553-60. doi: 10.1124/jpet.112.202226. Epub 2012 Dec 28.


Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.

Bell RL, Sable HJ, Colombo G, Hyytia P, Rodd ZA, Lumeng L.

Pharmacol Biochem Behav. 2012 Nov;103(1):119-55. doi: 10.1016/j.pbb.2012.07.007. Epub 2012 Jul 25. Review.


Comparison of the effect of the GABAΒ receptor agonist, baclofen, and the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in 3 different lines of alcohol-preferring rats.

Maccioni P, Zaru A, Loi B, Lobina C, Carai MA, Gessa GL, Capra A, Mugnaini C, Pasquini S, Corelli F, Hyytiä P, Lumeng L, Colombo G.

Alcohol Clin Exp Res. 2012 Oct;36(10):1748-66. doi: 10.1111/j.1530-0277.2012.01782.x. Epub 2012 Apr 6.


Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons.

Koek W, France CP, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2012 May;341(2):369-76. doi: 10.1124/jpet.111.190975. Epub 2012 Feb 7.


Reduction by the Positive Allosteric Modulator of the GABA(B) Receptor, GS39783, of Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats Exposed to the "Sipper" Procedure.

Maccioni P, Flore P, Carai MA, Mugnaini C, Pasquini S, Corelli F, Gessa GL, Colombo G.

Front Psychiatry. 2010 Jul 19;1:20. doi: 10.3389/fpsyt.2010.00020. eCollection 2010.


Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats.

Vlachou S, Guery S, Froestl W, Banerjee D, Benedict J, Finn MG, Markou A.

Psychopharmacology (Berl). 2011 May;215(1):117-28. doi: 10.1007/s00213-010-2119-x. Epub 2010 Dec 22.


GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.

Koek W, France CP, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2010 Oct;335(1):163-71. doi: 10.1124/jpet.110.171116. Epub 2010 Jul 13.


GABA(A) receptors in the dorsal raphé nucleus of mice: escalation of aggression after alcohol consumption.

Takahashi A, Kwa C, Debold JF, Miczek KA.

Psychopharmacology (Berl). 2010 Sep;211(4):467-77. doi: 10.1007/s00213-010-1920-x. Epub 2010 Jun 30.


Allosteric modulators of GABA(B) receptors: mechanism of action and therapeutic perspective.

Pin JP, Prézeau L.

Curr Neuropharmacol. 2007 Sep;5(3):195-201. doi: 10.2174/157015907781695919.


Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats.

Paterson NE, Vlachou S, Guery S, Kaupmann K, Froestl W, Markou A.

J Pharmacol Exp Ther. 2008 Jul;326(1):306-14. doi: 10.1124/jpet.108.139204. Epub 2008 Apr 29.

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