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Items: 1 to 20 of 85


Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems.

Mouhid L, Corzo-Martínez M, Torres C, Vázquez L, Reglero G, Fornari T, Ramírez de Molina A.

J Oncol. 2017;2017:7351976. doi: 10.1155/2017/7351976. Epub 2017 May 7. Review.


The KEAP1-NRF2 System in Cancer.

Taguchi K, Yamamoto M.

Front Oncol. 2017 May 4;7:85. doi: 10.3389/fonc.2017.00085. eCollection 2017. Review.


Controversy about pharmacological modulation of Nrf2 for cancer therapy.

Milkovic L, Zarkovic N, Saso L.

Redox Biol. 2017 Aug;12:727-732. doi: 10.1016/j.redox.2017.04.013. Epub 2017 Apr 8. Review.


The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer.

Yang M, Wang H, Zhou M, Liu W, Kuang P, Liang H, Yuan Q.

Oncotarget. 2016 Nov 22;7(47):76656-76666. doi: 10.18632/oncotarget.12307.


Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.

Dinkova-Kostova AT, Kostov RV, Canning P.

Arch Biochem Biophys. 2017 Mar 1;617:84-93. doi: 10.1016/ Epub 2016 Aug 3. Review.


Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane.

Bauman JE, Zang Y, Sen M, Li C, Wang L, Egner PA, Fahey JW, Normolle DP, Grandis JR, Kensler TW, Johnson DE.

Cancer Prev Res (Phila). 2016 Jul;9(7):547-57. doi: 10.1158/1940-6207.CAPR-15-0290. Epub 2016 Jun 23.


Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.

Thomson CA, Ho E, Strom MB.

Nutr Rev. 2016 Jul;74(7):432-43. doi: 10.1093/nutrit/nuw010. Epub 2016 May 31.


Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein.

Chatterjee N, Tian M, Spirohn K, Boutros M, Bohmann D.

PLoS Genet. 2016 May 27;12(5):e1006072. doi: 10.1371/journal.pgen.1006072. eCollection 2016 May.


Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane.

Yang L, Palliyaguru DL, Kensler TW.

Semin Oncol. 2016 Feb;43(1):146-53. doi: 10.1053/j.seminoncol.2015.09.013. Epub 2015 Sep 8. Review.


Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?

Houghton CA, Fassett RG, Coombes JS.

Oxid Med Cell Longev. 2016;2016:7857186. doi: 10.1155/2016/7857186. Epub 2016 Jan 6. Review.


Dietary Broccoli Lessens Development of Fatty Liver and Liver Cancer in Mice Given Diethylnitrosamine and Fed a Western or Control Diet.

Chen YJ, Wallig MA, Jeffery EH.

J Nutr. 2016 Mar;146(3):542-50. doi: 10.3945/jn.115.228148. Epub 2016 Feb 10.


Bioavailability of Plant-Derived Antioxidants.

Abourashed EA.

Antioxidants (Basel). 2013 Nov 5;2(4):309-25. doi: 10.3390/antiox2040309. Review.


The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance.

Furfaro AL, Traverso N, Domenicotti C, Piras S, Moretta L, Marinari UM, Pronzato MA, Nitti M.

Oxid Med Cell Longev. 2016;2016:1958174. doi: 10.1155/2016/1958174. Epub 2015 Nov 30. Review.


Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase.

Fahey JW, Holtzclaw WD, Wehage SL, Wade KL, Stephenson KK, Talalay P.

PLoS One. 2015 Nov 2;10(11):e0140963. doi: 10.1371/journal.pone.0140963. eCollection 2015.


Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.

Atwell LL, Zhang Z, Mori M, Farris PE, Vetto JT, Naik AM, Oh KY, Thuillier P, Ho E, Shannon J.

Cancer Prev Res (Phila). 2015 Dec;8(12):1184-91. doi: 10.1158/1940-6207.CAPR-15-0119. Epub 2015 Oct 28.


Organelle Simple Sequence Repeat Markers Help to Distinguish Carpelloid Stamen and Normal Cytoplasmic Male Sterile Sources in Broccoli.

Shu J, Liu Y, Li Z, Zhang L, Fang Z, Yang L, Zhuang M, Zhang Y, Lv H.

PLoS One. 2015 Sep 25;10(9):e0138750. doi: 10.1371/journal.pone.0138750. eCollection 2015.


Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury.

Yoshida K, Ushida Y, Ishijima T, Suganuma H, Inakuma T, Yajima N, Abe K, Nakai Y.

World J Gastroenterol. 2015 Sep 21;21(35):10091-103. doi: 10.3748/wjg.v21.i35.10091.


Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways.

Brown RH, Reynolds C, Brooker A, Talalay P, Fahey JW.

Respir Res. 2015 Sep 15;16:106. doi: 10.1186/s12931-015-0253-z.


A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer.

Alumkal JJ, Slottke R, Schwartzman J, Cherala G, Munar M, Graff JN, Beer TM, Ryan CW, Koop DR, Gibbs A, Gao L, Flamiatos JF, Tucker E, Kleinschmidt R, Mori M.

Invest New Drugs. 2015 Apr;33(2):480-9. doi: 10.1007/s10637-014-0189-z. Epub 2014 Nov 29.

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