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Items: 1 to 20 of 44


Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes.

Qu F, Lorenzo DN, King SJ, Brooks R, Bear JE, Bennett V.

Elife. 2016 Oct 8;5. pii: e20417. doi: 10.7554/eLife.20417.


Arf proteins in cancer cell migration.

Casalou C, Faustino A, Barral DC.

Small GTPases. 2016 Oct;7(4):270-282. Epub 2016 Sep 2.


Allosteric properties of PH domains in Arf regulatory proteins.

Roy NS, Yohe ME, Randazzo PA, Gruschus JM.

Cell Logist. 2016 Apr 26;6(2):e1181700. eCollection 2016 Apr-Jun. Review.


Mechanisms of T cell organotropism.

Fu H, Ward EJ, Marelli-Berg FM.

Cell Mol Life Sci. 2016 Aug;73(16):3009-33. doi: 10.1007/s00018-016-2211-4. Epub 2016 Apr 1. Review.


MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.

Vu HL, Rosenbaum S, Capparelli C, Purwin TJ, Davies MA, Berger AC, Aplin AE.

J Invest Dermatol. 2016 Feb;136(2):453-63. doi: 10.1016/j.jid.2015.11.012. Epub 2015 Nov 20.


ArfGAPs: key regulators for receptor sorting.

Shiba Y, Randazzo PA.

Receptors Clin Investig. 2014 Jun 13;1(5):e158.


Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS.

Franssen EH, Zhao RR, Koseki H, Kanamarlapudi V, Hoogenraad CC, Eva R, Fawcett JW.

J Neurosci. 2015 May 27;35(21):8359-75. doi: 10.1523/JNEUROSCI.2850-14.2015.


The Arf GTPase-activating protein family is exploited by Salmonella enterica serovar Typhimurium to invade nonphagocytic host cells.

Davidson AC, Humphreys D, Brooks AB, Hume PJ, Koronakis V.

MBio. 2015 Feb 10;6(1). pii: e02253-14. doi: 10.1128/mBio.02253-14.


Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival.

Xu B, Jin X, Min L, Li Q, Deng L, Wu H, Lin G, Chen L, Zhang H, Li C, Wang L, Zhu J, Wang W, Chu F, Shen J, Li H, Mao J.

Oncotarget. 2015 Feb 10;6(4):2434-50.


The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic.

Chen PW, Luo R, Jian X, Randazzo PA.

J Biol Chem. 2014 Oct 31;289(44):30237-48. doi: 10.1074/jbc.M114.596155. Epub 2014 Sep 15.


Enterohaemorrhagic Escherichia coli inhibits recycling endosome function and trafficking of surface receptors.

Clements A, Stoneham CA, Furniss RC, Frankel G.

Cell Microbiol. 2014 Nov;16(11):1693-705. doi: 10.1111/cmi.12319. Epub 2014 Jul 7.


Overexpression of DCF1 inhibits glioma through destruction of mitochondria and activation of apoptosis pathway.

Xie Y, Li Q, Yang Q, Yang M, Zhang Z, Zhu L, Yan H, Feng R, Zhang S, Huang C, Liu Z, Wen T.

Sci Rep. 2014 Jan 15;4:3702. doi: 10.1038/srep03702.


Endocytosis and cancer.

Mellman I, Yarden Y.

Cold Spring Harb Perspect Biol. 2013 Dec 1;5(12):a016949. doi: 10.1101/cshperspect.a016949. Review.


The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration.

Elloul S, Kedrin D, Knoblauch NW, Beck AH, Toker A.

Mol Cancer Res. 2014 Mar;12(3):464-76. doi: 10.1158/1541-7786.MCR-13-0398. Epub 2013 Nov 22.


Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells.

Tawadros T, Brown MD, Hart CA, Clarke NW.

Br J Cancer. 2012 Nov 6;107(10):1737-44. doi: 10.1038/bjc.2012.457. Epub 2012 Oct 4.


Integrin trafficking at a glance.

Bridgewater RE, Norman JC, Caswell PT.

J Cell Sci. 2012 Aug 15;125(Pt 16):3695-701. doi: 10.1242/jcs.095810. Review. No abstract available.


PKD controls αvβ3 integrin recycling and tumor cell invasive migration through its substrate Rabaptin-5.

Christoforides C, Rainero E, Brown KK, Norman JC, Toker A.

Dev Cell. 2012 Sep 11;23(3):560-72. doi: 10.1016/j.devcel.2012.08.008.


RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate.

Shi A, Liu O, Koenig S, Banerjee R, Chen CC, Eimer S, Grant BD.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2306-15. doi: 10.1073/pnas.1205278109. Epub 2012 Aug 6.


Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.

Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H.

J Cell Biol. 2012 Jun 25;197(7):983-96. doi: 10.1083/jcb.201201065.


Mechanistic insights into regulated cargo binding by ACAP1 protein.

Bai M, Pang X, Lou J, Zhou Q, Zhang K, Ma J, Li J, Sun F, Hsu VW.

J Biol Chem. 2012 Aug 17;287(34):28675-85. doi: 10.1074/jbc.M112.378810. Epub 2012 May 29.

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