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Items: 7


Structural basis of head to head polyketide fusion by CorB.

Zocher G, Vilstrup J, Heine D, Hallab A, Goralski E, Hertweck C, Stahl M, Schäberle TF, Stehle T.

Chem Sci. 2015 Nov 13;6(11):6525-6536. doi: 10.1039/c5sc02488a. Epub 2015 Aug 6.


Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.

Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10316-21. doi: 10.1073/pnas.1607210113. Epub 2016 Aug 29.


Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli.

Yang J, Xian M, Su S, Zhao G, Nie Q, Jiang X, Zheng Y, Liu W.

PLoS One. 2012;7(4):e33509. doi: 10.1371/journal.pone.0033509. Epub 2012 Apr 27.


Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin.

Skaff DA, Ramyar KX, McWhorter WJ, Barta ML, Geisbrecht BV, Miziorko HM.

Biochemistry. 2012 Jun 12;51(23):4713-22. doi: 10.1021/bi300037k. Epub 2012 May 25.


Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.

Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH.

Chem Biol. 2010 Oct 29;17(10):1092-100. doi: 10.1016/j.chembiol.2010.08.008.


Enzymes of the mevalonate pathway of isoprenoid biosynthesis.

Miziorko HM.

Arch Biochem Biophys. 2011 Jan 15;505(2):131-43. doi: 10.1016/ Epub 2010 Oct 7. Review.


Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases.

Pojer F, Ferrer JL, Richard SB, Nagegowda DA, Chye ML, Bach TJ, Noel JP.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11491-6. Epub 2006 Jul 24.

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